| Inmate Name | Register Number | Photo | Status | Details |
| Whitey Bulger | 02182-748 | | Served life sentences plus 5 years under his real name, James J. Bulger. Murdered in 2018 upon arrival at USP Hazelton. | Former leader of the Winter Hill Gang in Massachusetts and FBI Ten Most Wanted fugitive; apprehended in 2011 after 16 years on the run; convicted in 2013 of ordering 11 murders, as well as extortion, money laundering and drug trafficking. Transferred in October 2018 to the Federal Transfer Center and then to USP Hazelton, where he was murdered less than 24 hours after arrival. |
| Benjamin Arellano Felix | 00678-748 | | Scheduled for release in 2032. Now at USP Lee | Former leader of the Tijuana Cartel in Mexico, pleaded guilty in 2013 to conspiracy and money laundering for directing the importation of thousands of tons of cocaine into the US; the cartel killed over 1,000 civilians and police officers over a 16-year period. |
| Louis Daidone | 39065-053 | | Serving a life sentence. | Former acting boss of the Lucchese crime family, convicted of racketeering, loan sharking, extortion, and for the 1989 murder of Tom Gilmore, a Lucchese associate. He was also convicted of the 1990 murder of Bruno Facciola, in which Daidone lured Facciola into a Brooklyn garage where he was killed, and also stuffed a dead canary in Facciola’s mouth. |
| Stephen Caracappa | 04597-748 | | Sentenced to life plus 80 years. Died in 2017. | Former NYPD detective; convicted in 2006 of taking bribes to carry out murders and leak law enforcement intelligence disclosing the identities of witnesses for then Lucchese crime family underboss Anthony "Gaspipe" Casso; his partner, Louis Eppolito, was sentenced to life plus 100 years. |
| Jorge Eduardo Costilla Sanchez | 59344-380 | | Serving a life sentence. | Leader of the Mexican Gulf Cartel, extradited from Mexico to the U.S in 2015 on narcotics charges for importing cocaine and marijuana to the U.S, as well as threatening two federal agents at gunpoint during the 1999 Matamoros standoff. |
| Vincent Basciano | 30694-054 | | Serving a life sentence. | Former boss of the Bonanno crime family, convicted in 2006 of the murder of Frank Santoro, later convicted in 2011 of ordering the murder of Bonnano associate Randolph Pizzolo. |
| Ronnie Thomas | 43322-037 | | Released from custody on November 10, 2022. | Leader of the Tree Top Pirus, a subset of the Bloods street gang in Maryland, and producer of the Stop Snitchin' video series; convicted in 2010 of racketeering for participating in murder conspiracy, drug trafficking and robbery. |
| Edgar Valdez Villarreal | 05658-748 | | Sentenced to 49 years. Scheduled for release in 2056. | American-Mexican drug lord, extradited to US on September 30, 2015. Will be released on 27 July 2056. |
| Ronell Wilson | 71460-053 | | Serving a life sentence. | Gang leader in Staten Island, New York; murdered NYPD Detectives James Nemorin and Rodney Andrews, who were conducting a sting operation to buy an illegal gun in 2003. Wilson was initially on death row before having his sentence reduced to life without parole on the grounds of that he was mentally disabled. |
| José Antonio Acosta Hernández | 92043-280 | | Sentenced to life imprisonment. | One of several known leaders of the Mexican gang La Línea. |
