Available structures
Available structuresPDBOrtholog search: A2ASS6%20or%20Q8WZ42%20or%20 A2ASS6%20or%20H0Y4J7 PDBe A2ASS6,Q8WZ42, A2ASS6,H0Y4J7 RCSB List of PDB id codes4UOW, 1BPV, 1G1C, 1NCT, 1NCU, 1TIT, 1TIU, 1TKI, 1TNM, 1TNN, 1WAA, 1YA5, 2A38, 2BK8, 2F8V, 2ILL, 2J8H, 2J8O, 2NZI, 2RQ8, 2WP3, 2WWK, 2WWM, 2Y9R, 3KNB, 3LCY, 3LPW, 3PUC, 3Q5O, 3QP3, 4C4K, 4JNW, 4O00, 4QEG, 5BS0
PDB
Ortholog search: A2ASS6%20or%20Q8WZ42%20or%20 A2ASS6%20or%20H0Y4J7 PDBe A2ASS6,Q8WZ42, A2ASS6,H0Y4J7 RCSB
List of PDB id codes
List of PDB id codes4UOW, 1BPV, 1G1C, 1NCT, 1NCU, 1TIT, 1TIU, 1TKI, 1TNM, 1TNN, 1WAA, 1YA5, 2A38, 2BK8, 2F8V, 2ILL, 2J8H, 2J8O, 2NZI, 2RQ8, 2WP3, 2WWK, 2WWM, 2Y9R, 3KNB, 3LCY, 3LPW, 3PUC, 3Q5O, 3QP3, 4C4K, 4JNW, 4O00, 4QEG, 5BS0
Aliases
TTN, CMD1G, CMH9, CMPD4, EOMFC, HMERF, LGMD2J, MYLK5, TMD, titin, SALMY, LGMDR10
External IDs
OMIM: 188840; MGI: 98864; HomoloGene: 130650; GeneCards: TTN; OMA:TTN - orthologs
Gene location (Human)
Gene location (Human)Chr.Chromosome 2 (human)Band2q31.2Start178,525,989 bpEnd178,830,802 bp
Chr.
Chromosome 2 (mouse)
Gene location (Mouse)
Gene location (Mouse)Chr.Chromosome 2 (mouse)Band2 C3|2 45.13 cMStart76,703,980 bpEnd76,982,547 bp
RNA expression pattern
RNA expression patternBgeeHumanMouse (ortholog)Top expressed inglutesSkeletal muscle tissue of biceps brachiitriceps brachii muscleSkeletal muscle tissue of rectus abdominisright ventriclethoracic diaphragmbody of tonguevastus lateralis muscledeltoid musclemyocardium of left ventricleTop expressed invastus lateralis muscledigastric muscletriceps brachii musclesternocleidomastoid muscleknee jointbody of femurtemporal muscleatriumintercostal musclemedial head of gastrocnemius muscleMore reference expression dataBioGPSMore reference expression data
Bgee
HumanMouse (ortholog)Top expressed inglutesSkeletal muscle tissue of biceps brachiitriceps brachii muscleSkeletal muscle tissue of rectus abdominisright ventriclethoracic diaphragmbody of tonguevastus lateralis muscledeltoid musclemyocardium of left ventricleTop expressed invastus lateralis muscledigastric muscletriceps brachii musclesternocleidomastoid muscleknee jointbody of femurtemporal muscleatriumintercostal musclemedial head of gastrocnemius muscleMore reference expression data
BioGPS
More reference expression data
Gene ontology
Gene ontologyMolecular function transferase activity nucleotide binding calcium ion binding protein kinase activity actinin binding muscle alpha-actinin binding structural molecule activity conferring elasticity metal ion binding telethonin binding protease binding protein self-association actin filament binding protein serine/threonine kinase activity kinase activity protein binding identical protein binding enzyme binding protein tyrosine kinase activity structural constituent of muscle ATP binding protein kinase binding calmodulin binding structural constituent of cytoskeleton ankyrin binding Cellular component cytoplasm cytosol I band striated muscle thin filament condensed nuclear chromosome extracellular region Z discdkac muscle myosin complex extracellular exosome nucleus M band sarcomere A band myofibril Biological process sarcomerogenesis muscle contraction mitotic chromosome condensation cardiac muscle contraction phosphorylation cardiac muscle hypertrophy platelet degranulation cardiac muscle tissue morphogenesis skeletal muscle thin filament assembly detection of muscle stretch response to calcium ion cardiac myofibril assembly protein phosphorylation muscle filament sliding regulation of protein kinase activity regulation of catalytic activity sarcomere organization skeletal muscle myosin thick filament assembly striated muscle contraction peptidyl-tyrosine phosphorylation positive regulation of gene expression protein kinase A signaling positive regulation of protein secretion somitogenesis ventricular system development in utero embryonic development heart morphogenesis striated muscle cell development heart growth adult heart development forward locomotion development of the heart regulation of relaxation of cardiac muscle actin filament organization striated muscle myosin thick filament assembly Sources:Amigo / QuickGO
Orthologs
OrthologsSpeciesHumanMouseEntrez727322138EnsemblENSG00000155657ENSMUSG00000051747UniProtQ8WZ42Q8WZ42RefSeq (mRNA)NM_001256850NM_001267550NM_003319NM_133378NM_133379NM_133432NM_133437NM_011652NM_028004RefSeq (protein)NP_001243779NP_001254479NP_003310NP_596869NP_596870NP_597676NP_597681NP_035782NP_082280NP_001372637NP_001243779NP_001254479NP_003310NP_596869NP_596870NP_597676NP_597681NP_035782NP_082280NP_001372637Location (UCSC)Chr 2: 178.53 – 178.83 MbChr 2: 76.7 – 76.98 MbPubMed search
RefSeq (mRNA)
NM_001256850NM_001267550NM_003319NM_133378NM_133379NM_133432NM_133437
RefSeq (protein)
NP_001243779NP_001254479NP_003310NP_596869NP_596870NP_597676NP_597681NP_035782NP_082280NP_001372637
Location (UCSC)
Chr 2: 178.53 – 178.83 Mb
