| Year | A-side/B-sideBoth sides from same album except where indicated | Label & reference | Chart Positions | Album |
| US | US CB | CAN(CHUM/RPM) | UK |
| 1965 | "Hang On Sloopy"b/w "I Can't Explain It" | Bang 506 | 1 | 1 | — | 5 | Hang On Sloopy |
| "Fever"b/w "Sorrow" | Bang 511 | 7 | 9 | 2 | 44 |
| 1966 | "Up and Down"b/w "If You Tell a Lie" (from Hang on Sloopy) | Bang 516 | 46 | 50 | 75 | — | Non-album track |
| "Come On, Let's Go"b/w "Little People" | Bang 522 | 22 | 17 | 36 | 51 | You Make Me Feel So Good |
| "(You Make Me Feel) So Good"b/w "Runaway" | Bang 527 | 53 | 53 | 42 | — |
| "Don't Worry Mother, Your Son's Heart Is Pure"b/w "Ko-Ko" | Bang 532 | 67 | 60 | 46 | — | Non-album tracks |
| 1967 | "I Got to Go Back (and Watch That Little Girl Dance)"b/w "Dynamite" (from You Make Me Feel So Good) | Bang 538 | 69 | 90 | 34 | — |
| "Beat The Clock"b/w "Like You Do to Me" | Bang 543 | 92 | 79 | — | — |
| "Say Those Magic Words"b/w "I Wonder If She Remembers Me" (Non-album track) | Bang 549 | — | — | — | — | You Make Me Feel So Good |
| 1968 | "Jesse Brady"b/w "Resurrection" | Mercury 72843 | 98 | 94 | — | — | Infinite McCoys |
| "Epilogue"b/w "Daybreak" | Mercury 72897 | — | — | — | — | Human Ball |
| 1969 | "Love Don't Stop"b/w "Only Human" | Mercury 72917 | — | — | — | — |
| "Don't Fight It"b/w "Rosa Rodrigues" | Mercury 72967 | — | — | — | — | Non-album tracks |
| "—" denotes releases that did not chart or were not released in that territory. |