| Mission and patch | Capsule | Launch date | Landing date | Launch pad | Landing site | Remarks | Crew | Outcome |
| Pad Abort Test (patch) | C201 DragonFly | May 6, 2015 | SLC-40 | Atlantic Ocean | Simulating an escape from a rocket failure on the ground, Crew Dragon's SuperDraco engines lifted the capsule from a ground pad at SLC-40 and propelled it to a safe splashdown in the nearby ocean. | — | Success |
| Demo-1 (patch) | C204 | March 2, 2019 | March 8, 2019 | LC-39A | Atlantic Ocean | Uncrewed orbital test flight, successfully docked with the ISS. | — | Success |
| In-Flight Abort Test (patch) | C205 | January 19, 2020 | LC-39A | Atlantic Ocean | Booster was commanded to simulate an in-flight engine failure. In response, Crew Dragon's SuperDraco engines fired successfully, propelling the capsule away to a safe splashdown. | — | Success |
| Demo-2 | C206‑1 Endeavour | May 30, 2020 | August 2, 2020 | LC-39A | Gulf of Mexico | First crewed flight test of Dragon 2. The mission was extended from two weeks to nine to allow the crew to bolster activity on the ISS ahead of Crew-1. | Doug HurleyBob Behnken | Success |
| Crew-1 | C207‑1 Resilience | November 16, 2020 | May 2, 2021 | LC-39A | Gulf of Mexico | First operational Commercial Crew flight. | Michael HopkinsVictor GloverSoichi NoguchiShannon Walker | Success |
| Crew-2 | C206‑2 Endeavour | April 23, 2021 | November 9, 2021 | LC-39A | Gulf of Mexico | First reuse of a capsule and booster rocket. | Shane KimbroughMegan McArthurAkihiko HoshideThomas Pesquet | Success |
| Inspiration4 (patch 1 and 2) | C207‑2 Resilience | September 16, 2021 | September 18, 2021 | LC-39A | Atlantic Ocean | The first fully private, all-civilian orbital flight. Crew reached a 585 km (364 mi) orbit and conducted science experiments and public outreach activities for three days. First standalone orbital Crew Dragon flight and the first flight with the cupola. | Jared IsaacmanSian ProctorHayley ArceneauxChristopher Sembroski | Success |
| Crew-3 | C210‑1 Endurance | November 11, 2021 | May 6, 2022 | LC-39A | Gulf of Mexico | | Raja ChariThomas MarshburnMatthias MaurerKayla Barron | Success |
| Axiom-1 (patch) | C206‑3 Endeavour | April 8, 2022 | April 25, 2022 | LC-39A | Atlantic Ocean | First fully private flight to the ISS. Contracted by Axiom Space. Axiom employee served as commander with three tourists. | Michael López-AlegríaLarry ConnorEytan StibbeMark Pathy | Success |
| Crew-4 | C212‑1 Freedom | April 27, 2022 | October 14, 2022 | LC-39A | Atlantic Ocean | | Kjell LindgrenBob HinesSamantha CristoforettiJessica Watkins | Success |
| Crew-5 | C210‑2 Endurance | October 5, 2022 | March 12, 2023 | LC-39A | Gulf of Mexico | First crew to include a Russian cosmonaut as part of Dragon–Soyuz seat swap program. | Nicole Aunapu MannJosh CassadaKoichi WakataAnna Kikina | Success |
| Crew-6 | C206‑4 Endeavour | March 2, 2023 | September 4, 2023 | LC-39A | Atlantic Ocean | | Stephen BowenWarren HoburgSultan Al NeyadiAndrey Fedyaev | Success |
| Axiom-2 (patch) | C212‑2 Freedom | May 21, 2023 | May 31, 2023 | LC-39A | Gulf of Mexico | Fully private flight to the ISS. Contracted by Axiom Space. Axiom employee served as commander, other seats purchased by SSA and a tourist. | Peggy WhitsonJohn ShoffnerAli AlQarniRayyanah Barnawi | Success |
| Crew-7 | C210‑3 Endurance | August 26, 2023 | March 12, 2024 | LC-39A | Gulf of Mexico | | Jasmin MoghbeliAndreas MogensenSatoshi FurukawaKonstantin Borisov | Success |
| Axiom-3 (patch) | C212‑3 Freedom | January 18, 2024 | February 9, 2024 | LC-39A | Atlantic Ocean | Fully private flight to the ISS. Axiom employee served as commander, other seats purchased by AM, TUA, and SNSA/ESA. | Michael López-AlegríaWalter VilladeiAlper GezeravcıMarcus Wandt | Success |
| Crew-8 | C206‑5 Endeavour | March 4, 2024 | October 25, 2024 | LC-39A | Gulf of Mexico | Longest Crew Dragon mission. ISS stay extended and two makeshift seats added to allow Crew-8 to serve as "lifeboat" for the Boeing CFT crew if needed. | Matthew DominickMichael BarrattJeanette EppsAlexander Grebenkin | Success |
| Polaris Dawn (patch) | C207‑3 Resilience | September 10, 2024 | September 15, 2024 | LC-39A | Gulf of Mexico | Fully private orbital flight, including two SpaceX employees. First of three planned flights of the private Polaris Program. Flew 1,400 km (870 mi) away from Earth, the highest orbit of the planet flown by a crewed spacecraft since the end of the Apollo program. Isaacman and Gillis made the first commercial spacewalk during the mission. | Jared IsaacmanScott PoteetSarah GillisAnna Menon | Success |
| Crew-9 | C212‑4 Freedom | September 28, 2024 | March 18, 2025 | SLC-40 | Gulf of Mexico | Was the first crewed mission to launch from SLC-40. Launched with only two crew members and returned with the crew of the Boeing Crew Flight Test due to issues with the Boeing Starliner Calypso. | Nick HagueAleksandr GorbunovBarry E. Wilmore (landing)Sunita Williams (landing) | Success |
| Crew-10 | C210‑4 Endurance | March 14, 2025 | August 9, 2025 | LC-39A | Pacific Ocean | | Anne McClainNichole AyersTakuya OnishiKirill Peskov | Success |
| Fram2 (patch) | C207‑4 Resilience | April 1, 2025 | April 4, 2025 | LC-39A | Pacific Ocean | Fully private, all-civilian orbital flight. First crewed mission to launch into an orbit over the planet's poles. First crewed Dragon landing on the West Coast. | Chun WangJannicke MikkelsenRabea RoggeEric Philips | Success |
| Axiom-4 (patch) | C213‑1 Grace | June 25, 2025 | July 15, 2025 | LC-39A | Pacific Ocean | Fully private flight to the ISS. Axiom employee served as commander; other seats purchased by ISRO, POLSA/ESA, and Hungary. | Peggy WhitsonShubhanshu ShuklaSławosz Uznański-WiśniewskiTibor Kapu | Success |
| Crew-11 | C206‑6 Endeavour | August 1, 2025 | April 2026 | LC-39A | Pacific Ocean (planned) | Fastest Crew Dragon rendezvous to date. | Zena CardmanMichael FinckeKimiya YuiOleg Platonov | In progress |
| Crew-12 | TBA | March 31, 2026 | October 2026 | TBA | Pacific Ocean (planned) | | TBATBASophie AdenotAndrey Fedyaev | Planned |
| Vast-1 | TBA | June 2026 | TBA | TBA | Pacific Ocean (planned) | Servicing of the Haven-1 space station. | TBA | Planned |
| Crew-13 | TBA | TBA | TBA | TBA | Pacific Ocean (planned) | | TBA | Planned |
| Crew-14 | TBA | TBA | TBA | TBA | Pacific Ocean (planned) | | TBA | Planned |
| Polaris-2 | TBA | TBA | TBA | TBA | Pacific Ocean (planned) | Last Polaris Program flight to use Crew Dragon (final flight plans to use Starship). | Jared IsaacmanTBATBATBA | Planned |