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Saiyami Kher is an Indian actress who primarily works in Hindi and Telugu films. Kher made her acting debut with the Telugu film Rey (2015) and her Hindi debut with Mirzya (2016), for which she received Stardust Award for Superstar of Tomorrow – Female. Kher has since appeared in Mauli (2018), Choked (2020), Wild Dog (2021) and Ghoomer (2023). She has also starred in the streaming series Special OPS (2020) and Faadu (2022).
| † | Denotes film or TV productions that have not yet been released |
| Year | Title | Role | Language | Notes | Ref. |
| 2015 | Rey | Amrutha | Telugu | ||
| 2016 | Mirzya | Suchitra | Hindi | ||
| 2018 | Mauli | Renuka | Marathi | ||
| 2020 | Choked | Sarita Pillai | Hindi | ||
| Unpaused | Ayesha Hussain | Segment: "Glitch" | |||
| 2021 | Wild Dog | Arya Pandit | Telugu | ||
| 2022 | Highway | Asha Bharath | |||
| 2023 | Metro | Iravati | Hindi | ||
| Ghoomer | Anina "Ani" Dixit | ||||
| 2024 | Sharmajee Ki Beti | Tanvi Sharma | |||
| Agni | Avni Purohit | ||||
| 2025 | Jaat | SI Vijaya Lakshmi | |||
| TBA | Haiwaan † | TBA | Completed |
| Year | Title | Role | Notes | Ref. |
| 2020 | Special OPS | Juhi Kashyap | Season 1 | |
| Breathe: Into the Shadows | Shirley | 2 seasons | ||
| 2022 | Faadu | Manjiri | ||
| 2025 | Special OPS | Juhi Kashyap | Season 2 |
| Year | Award | Category | Work | Result | Ref. |
| 2016 | Stardust Awards | Superstar of Tomorrow – Female | Mirzya | Won | |
| 2020 | Filmfare OTT Awards | Best Actor Female in Web Original Film | Choked | Nominated | |
| 2024 | 69th Filmfare Awards | Filmfare Critics Award for Best Actress | Ghoomer | Nominated | |
| Iconic Gold Awards | Powerpacked Performance of the Year - Female | Won |