| Congress | Years | Democratic whip | Democratic leader | Speaker | Republican leader | Republican whip | | president |
| 56th | 1899–1901 | Oscar Underwood(Alabama) | James D. Richardson(Tennessee) | — GOP majority –David B. Henderson(Iowa) | Sereno E. Payne(New York) | James Albertus Tawney(Minnesota) | William McKinley(Republican) |
| 57th | 1901–1903 | James Tilghman Lloyd(Missouri) | Theodore Roosevelt(Republican) |
| 58th | 1903–1905 | John Sharp Williams(Mississippi) | — GOP majority –Joe Cannon(Illinois) |
| 59th | 1905–1907 | James E. Watson(Indiana) |
| 60th | 1907–1908 |
| 1908–1909 |
| 61st | 1909–1911 | None | Champ Clark(Missouri) | John W. Dwight(New York) | William Howard Taft(Republican) |
| 62nd | 1911–1913 | Oscar Underwood(Alabama) | — Dem majority –Champ Clark(Missouri) | James Mann(Illinois) |
| 63rd | 1913–1915 | Thomas M. Bell(Georgia) | Charles H. Burke(South Dakota) | Woodrow Wilson(Democratic) |
| 64th | 1915–1917 | None | Claude Kitchin(North Carolina) | Charles M. Hamilton(New York) |
| 65th | 1917–1919 |
| 66th | 1919–1921 | Champ Clark(Missouri) | — GOP majority –Frederick H. Gillett(Massachusetts) | Frank W. Mondell(Wyoming) | Harold Knutson(Minnesota) |
| 67th | 1921–1923 | William A. Oldfield(Arkansas) | Claude Kitchin(North Carolina) | Warren G. Harding(Republican) |
| 68th | 1923–1925 | Finis J. Garrett(Tennessee) | Nicholas Longworth(Ohio) | Albert H. Vestal(Indiana) | Calvin Coolidge(Republican) |
| 69th | 1925–1927 | — GOP majority –Nicholas Longworth(Ohio) | John Q. Tilson(Connecticut) |
| 70th | 1927–1929 |
| 71st | 1929–1931 | John McDuffie(Alabama) | John Nance Garner(Texas) | Herbert Hoover(Republican) |
| 72nd | 1931–1933 | Henry T. Rainey(Illinois) | — Dem majority –John Nance Garner(Texas) | Bertrand Snell(New York) | Carl G. Bachmann(West Virginia) |
| 73rd | 1933–1935 | Arthur H. Greenwood(Indiana) | Jo Byrns(Tennessee) | — Dem majority –Henry T. Rainey(Illinois) | Harry L. Englebright(California) | Franklin D. Roosevelt(Democratic) |
| 74th | 1935–1936 | Patrick J. Boland(Pennsylvania) | William B. Bankhead(Alabama) | — Dem majority –Jo Byrns(Tennessee) |
| 1936–1937 | Sam Rayburn(Texas) | — Dem majority –William B. Bankhead(Alabama) |
| 75th | 1937–1939 |
| 76th | 1939–1940 | Joseph W. Martin Jr.(Massachusetts) |
| 1940–1941 | John W. McCormack(Massachusetts) | — Dem majority –Sam Rayburn(Texas) |
| 77th | 1941–1942 |
| 1942–1943 | Robert Ramspeck(Georgia) |
| 78th | 1943 |
| 1943–1945 | Leslie Arends(Illinois) |
| 79th | 1945 | Harry S. Truman(Democratic) |
| 1946–1947 | John Sparkman(Alabama) |
| 80th | 1947–1949 | John W. McCormack(Massachusetts) | Sam Rayburn(Texas) | — GOP majority –Joseph W. Martin Jr.(Massachusetts) | Charles A. Halleck(Indiana) |
| 81st | 1949–1951 | Percy Priest(Tennessee) | John W. McCormack(Massachusetts) | — Dem majority –Sam Rayburn(Texas) | Joseph W. Martin Jr.(Massachusetts) |
| 82nd | 1951–1953 |
| 83rd | 1953–1955 | John W. McCormack(Massachusetts) | Sam Rayburn(Texas) | — GOP majority –Joseph W. Martin Jr.(Massachusetts) | Charles A. Halleck(Indiana) | Dwight D. Eisenhower(Republican) |
| 84th | 1955–1957 | Carl Albert(Oklahoma) | John W. McCormack(Massachusetts) | — Dem majority –Sam Rayburn(Texas) | Joseph W. Martin Jr.(Massachusetts) |
| 85th | 1957–1959 |
| 86th | 1959–1961 | Charles A. Halleck(Indiana) |
| 87th | 1961–1962 | John F. Kennedy(Democratic) |
| 1962–1963 | Hale Boggs(Louisiana) | Carl Albert(Oklahoma) | — Dem majority –John W. McCormack(Massachusetts) |
| 88th | 1963–1965 | Lyndon B. Johnson(Democratic) |
| 89th | 1965–1967 | Gerald Ford(Michigan) |
| 90th | 1967–1969 |
| 91st | 1969–1971 | Richard Nixon(Republican) |
| 92nd | 1971–1973 | Tip O'Neill(Massachusetts) | Hale Boggs(Louisiana) | — Dem majority –Carl Albert(Oklahoma) |
| 93rd | 1973 | John J. McFall(California) | Tip O'Neill(Massachusetts) |
| 1973–1975 | John Rhodes(Arizona) |
| 94th | 1975–1977 | Bob Michel(Illinois) | Gerald Ford(Republican) |
| 95th | 1977–1979 | John Brademas(Indiana) | Jim Wright(Texas) | — Dem majority –Tip O'Neill(Massachusetts) | Jimmy Carter(Democratic) |
| 96th | 1979–1981 |