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Nimisha Sajayan is an Indian actress who primarily works in Malayalam films, apart from Tamil and Hindi films. Nimisha made her acting debut with the film Thondimuthalum Driksakshiyum directed by Dileesh Pothan. She won the Kerala State Film Award for Best Actress in 2018 for her performance in Oru Kuprasidha Payyan and Chola. She is also a recipient of three Filmfare Awards.
| † | Denotes film or TV productions that have not yet been released |
| Year | Title | Role | Language | Notes | Ref. |
| 2017 | Thondimuthalum Driksakshiyum | Sreeja | Malayalam | ||
| 2018 | Eeda | Aishwarya | |||
| Mangalyam Thanthunanena | Clara | ||||
| Oru Kuprasidha Payyan | Hanna Elizabeth | ||||
| 2019 | Nalpathiyonnu (41) | Bhagyasooyam | |||
| Chola | Janaki | ||||
| Stand Up | Keerthi | ||||
| 2021 | The Great Indian Kitchen | Sreedevi Hareesh | |||
| One | Lathika | ||||
| Nayattu | WCPO Sunitha | ||||
| Malik | Rosline | ||||
| 2022 | Innale Vare | Anjali | |||
| Heaven | Defense councilor | Cameo | |||
| Hawa Hawai | Jyoti | Marathi | |||
| Oru Thekkan Thallu Case | Vasanthi | Malayalam | |||
| 2023 | Thuramukham | Umani | |||
| Footprints on Water | Meera | Indian English | |||
| Chithha | Shakthi | Tamil | |||
| Jigarthanda DoubleX | Malaiyarasi | ||||
| Adrishya Jalakangal | Miranda | Malayalam | |||
| 2024 | Mission: Chapter 1 | Nancy Kurian | Tamil | ||
| Lantrani | Manasi Gangopandhey | Hindi | |||
| 2025 | Crazxy | Bobby | Voice role | ||
| DNA | Dhivya Anand | Tamil |
| Year | Title | Role | Notes | Ref. |
| 2017 | Nethram | Rape victim | ||
| 2020 | Ghar Se | Wife | Hindi short film | |
| Draupadi | Mother | Photo Story |
| † | Denotes series that have not yet been released |
| Year | Title | Role | Language | Notes | Ref. |
| 2024 | Poacher | Mala Yogi | Malayalam | TV series on Prime Video | |
| 2025 | Dabba Cartel | Mala | Hindi | TV series on Netflix |
| Award | Year | Category | Work | Result | Ref. |
| Kerala State Film Awards | 2019 | Best Actress | Oru Kuprasidha PayyanChola | Won | |
| Kerala Film Critics Association Awards | Best Actress | Oru Kuprasidha Payyan | Won | ||
| Filmfare Awards South | 2018 | Best Actress (Malayalam) | Thondimuthalum Driksakshiyum | Nominated | |
| South Indian International Movie Awards | Best Female Debut – Malayalam | Won | |||
| Best Actress – Malayalam | Nominated | ||||
| Asianet Film Awards | Best Actress | Nominated | |||
| 2019 | Best Star Couple (shared with Shane Nigam) | Eeda | Won | ||
| Best Character Actress | Oru Kuprasidha Payyan | Nominated | |||
| Filmfare Awards South | 2019 | Best Actress | Eeda | Nominated | |
| Best Actress (Critics) | Won | ||||
| Vanitha Film Awards | 2018 | Best Newcomer Actress | Thondimuthalum Driksakshiyum | Won | |
| IFFM Awards | 2021 | Best Performance Female (Feature) | The Great Indian Kitchen | Nominated | |
| Honourable Mention for Best Actress (Feature) | Won | ||||
| Movie Street Film Excellence Awards | 2018 | Best Debutant Actor – Female | Thondimuthalum Driksakshiyum | Won | |
| 2019 | Best Actor (Female) | Oru Kuprasidha Payyan | Won | ||
| Toronto International South Asian Film Awards | Best Debut Actress | Thondimuthalum Driksakshiyum | Won | ||
| South Indian International Movie Awards | 2021 | Best Actress | Chola | Nominated | |
| Best Actress – (Critics) | Won | ||||
| Filmfare Awards South | 2022 | Best Actress (Malayalam) | The Great Indian Kitchen | Won | |
| South Indian International Movie Awards | Critics Choice Awards | Won | |||
| Filmfare Awards South | 2024 | Best Actress | Chithha | Won | |
| Ananda Vikatan Cinema Awards | Best Actress | Won |