| Launch No. | Date | Vehicle | Apogee | Passengers | Outcome | Notes |
| 0 | October 19, 2012 | mw- .mw- N/ARSS Jules Verne | 0.7 km (0.4369 mi) | — | Success | Pad abort test of the New Shepard capsule. |
| 1 | April 29, 2015 | NS1RSS Jules Verne | 93.5 km (58.1 mi) | — | Partial success | Capsule recovered, rocket crashed on landing. Blue Origin deemed mission successful. |
| 2 | November 23, 201517:21 | RSS Jules Verne | 100.5 km (62.5 mi) | — | Success | Sub-orbital spaceflight and landing. |
| 3 | January 22, 2016 | RSS Jules Verne | 101.7 km (63.2 mi) | — | Success | Sub-orbital spaceflight and landing of a reused rocket. |
| 4 | April 2, 201615:18 | RSS Jules Verne | 103.4 km (64.2 mi) | — | Success | Sub-orbital spaceflight and landing of a reused rocket. |
| 5 | June 19, 201614:36 | RSS Jules Verne | 101.0 km (62.8 mi) | — | Success | Sub-orbital spaceflight and landing of a reused rocket: the fourth launch and landing of the same rocket. Blue Origin published a live webcast of the takeoff and landing. |
| 6 | October 5, 201615:36 | RSS Jules Verne | Rocket: 93.7 km (58.2 mi)Capsule: 7.1 km (4.4 mi) | — | Success | Sub-orbital spaceflight and landing of a reused rocket. Successful test of the in-flight abort system. The fifth and final launch and landing of the same rocket (NS2). |
| 7 | December 12, 201716:59 | RSS H. G. Wells | Rocket: 98.2 km (61.0 mi)Capsule: 98.3 km (61.1 mi) | — | Success | Flight to just under 100 km and landing. The first launch of NS3 and a new Crew Capsule 2.0. |
| 8 | April 29, 201817:06 | RSS H. G. Wells | 107.0 km (66.5 mi) | — | Success | Sub-orbital spaceflight and landing of a reused rocket. |
| 9 | July 18, 201815:11 | RSS H. G. Wells | 118.8 km (73.8 mi) | — | Success | Sub-orbital spaceflight and landing of a reused rocket, with capsule carrying a mannequin. Successful test of the in-flight abort system at high altitude. Flight duration was 11 minutes. |
| 10 | January 23, 201914:05 | RSS H. G. Wells | c. 106.9 km (66.4 mi) | — | Success | Sub-orbital flight, delayed from December 18, 2018. Eight NASA research and technology payloads were flown. |
| 11 | May 2, 201913:34 | RSS H. G. Wells | c. 105.5 km (65.5 mi) | — | Success | Sub-orbital flight. Maximum Ascent Velocity: 3,568 km/h (2,217 mph), duration: 10 minutes, 10 seconds. Payload: 38 microgravity research payloads (nine sponsored by NASA). |
| 12 | December 11, 201917:53 | RSS H. G. Wells | c. 104.5 km (64.9 mi) | — | Success | Sub-orbital flight, Payload: Multiple commercial, research (8 sponsored by NASA) and educational payloads, including postcards from Club for the Future. The sixth launch and landing of the same rocket. |
| 13 | October 13, 202013:37 | RSS H. G. Wells | c. 107.0 km (66.5 mi) | — | Success | 7th flight of the same capsule/rocket. Onboard 12 payloads include Space Lab Technologies, Southwest Research Institute, postcards and seeds for Club for the Future, and multiple payloads for NASA including SPLICE to test future lunar landing technologies in support of the Artemis program. |
| 14 | January 14, 202116:57 | RSS First Step | Rocket: 106.9 km (66.5 mi)Capsule: 107.1 km (66.5 mi) | — | Success | Qualification flight for NS4 rocket and capsule and maiden flight for NS4 |
| 15 | April 14, 202116:51 | RSS First Step | Rocket: 106.9 km (66.4 mi)Capsule: 107.1 km (66.5 mi) | — | Success | Second flight of NS4, first preflight human passenger process test where Blue Origin conducted an "Astronaut Rehearsal". Gary Lai, Susan Knapp, Clay Mowry, and Audrey Powers, all Blue Origin personnel, were "stand-in astronauts". Lai and Powers briefly entered the capsule during the test. |
| 16 | July 20, 202113:12 | RSS First Step | Rocket: 105.8 km (65.8 mi)Capsule: 107.0 km (66.5 mi) | Jeff BezosMark BezosWally FunkOliver Daemen | Success | First flight of New Shepard with passengers. |
| 17 | August 25, 202114:31 | RSS H. G. Wells | Rocket: 105.8 km (65.7 mi)Capsule: 105.9 km (65.8 mi) | — | Success | Payload mission consisting of 18 commercial payloads inside the capsule, a NASA lunar landing technology demonstration installed on the exterior of the rocket and an art installation installed on the exterior of the capsule. |
| 18 | October 13, 202114:49 | RSS First Step | Rocket: 106.9 km (66.4 mi)Capsule: 107.0 km (66.5 mi) | Chris BoshuizenGlen de VriesWilliam ShatnerAudrey Powers | Success | |
| 19 | December 11, 202110:50 | RSS First Step | Rocket: 106.9 km (66.4 mi)Capsule: 107.1 km (66.5 mi) | Lane BessCameron BessEvan DickLaura Shepard ChurchleyMichael StrahanDylan Taylor | Success | |
| 20 | March 31, 202213:57 | RSS First Step | Rocket: 107.0 km (66.5 mi)Capsule: 107.1 km (66.5 mi) | Marty AllenSharon HagleMarc HagleJim KitchenGeorge NieldGary Lai | Success | |
| 21 | June 4, 202213:25 | RSS First Step | Rocket: 106.9 km (66.4 mi)Capsule: 107.0 km (66.5 mi) | Evan DickKatya EchazarretaHamish HardingVictor Correa HespanhaJaison RobinsonVictor Vescovo | Success | |
| 22 | August 4, 202213:56 | RSS First Step | Rocket: 106.9 km (66.5 mi)Capsule: 107.1 km (66.5 mi) | Coby CottonMário FerreiraVanessa O'BrienClint Kelly IIISara SabrySteve Young | Success | |
| 23 | September 12, 202214:27 | RSS H. G. Wells | 11.4 km (7.1 mi) | — | Failure | Research mission with 36 commercial payloads on board including two on the exterior of the rocket. The spacecraft's launch escape system activated after the rocket's BE-3 main engine failed around a minute after liftoff leading to a loss of control. The capsule was safely recovered whilst the rocket was lost as it impacted on ground. |
| 24 | December 1, 202316:43 | RSS H. G. Wells | Rocket: 106.9 km (66.4 mi)Capsule: 107.1 km (66.5 mi) | — | Success | Successful Return to Flight mission following failure of NS-23 more than a year prior. 33 payloads and 38,000 Club for the Future postcards from students around the world. |
| 25 | May 19, 202413:30 | RSS First Step | c. 106 km | Kenneth HessSylvain ChironMason AngelEd DwightCarol SchallerGopi Thotakura | Success | |
| 26 | August 29, 202413:07 | RSS First Step | Capsule: 105.3 km (65.4 mi) | Ephraim RabinNicolina ElrickEugene GrinRob FerlKarsen KitchenEiman Jahangir | Success | |
| 27 | October 23, 202415:27 | RSS Kármán Line | Capsule: 101 km (63 mi) | — | Success | First flight of Propulsion Module NS5 and capsule RSS Kármán Line. 12 payloads and tens of thousands of Club for the Future postcards. |
| 28 | November 22, 202415:30 | RSS First Step | Capsule 107.08 km (66.54 mi) | Emily CalandrelliSharon HagleMarc HagleAustin LitteralJames "J.D." RussellHenry Wolfond | Success | |
| 29 | February 4, 202516:00 | RSS H. G. Wells | Rocket: 105.3 km (65.4 mi)Capsule: 105.3 km (65.5 mi) | — | Success | Research mission on behalf of NASA, simulated lunar gravity by spinning the capsule at 11 rpm using the spacecraft's reaction control system. 30 payloads, 29 internal and one external. |
| 30 | February 25, 202515:49 | RSS First Step | Rocket: 106.5 km (66.2 mi)Capsule: 106.4 km (66.1 mi) | Lane BessJesús CallejaTushar ShahRichard ScottElaine Chia HydeRussell Wilson | Success | |
| 31 | April 14, 202513:30 | RSS Kármán Line | Rocket: 106.7 km (66.3 mi)Capsule: 106.8 km (66.4 mi) | Aisha BoweAmanda NguyenGayle KingKaty PerryKerianne FlynnLauren Sánchez | Success | |
| 32 | May 31, 202513:39 | RSS First Step | | Aymette Medina JorgeGretchen GreenJaime AlemánJesse WilliamsMark RocketPaul Jeris | Success | |
| 33 | June 29, 202514:40 | RSS Kármán Line | | Allie KuehnerCarl KuehnerLeland LarsonFreddie Rescigno, Jr.Owolabi SalisJames Sitkins | Success | |
| 34 | August 3, 202512:42 | RSS First Step | | Arvi BahalGökhan ErdemDeborah MartorellLionel PitchfordJ. D. RussellJustin Sun | Success | |
| 35 | September 18, 202513:00 | RSS H. G. Wells | | — | Success | Uncrewed flight that flew more than 40 scientific and research payloads to space and back. These payloads include 24 experiments from NASA’s TechRise Student Challenge, and payloads for Johns Hopkins Applied Physics Laboratory, University, College, Teledyne, Space Lab Technologies, and Teachers in Space, among others. Final flight for RSS H. G. Wells. |
| 36 | October 8, 202513:40 | RSS First Step | | Jeff ElginDanna KaragussovaClint Kelly IIIAaron NewmanVitalii OstrovskyWilliam H. Lewis | Success | |
| 37 | TBD | TBD | | Michaela BenthausJoey HydeHans KoenigsmannNeal MilchAdonis PouroulisJason Stansell | Planned | Announced in December 2025. Benthaus is expected to become the first wheelchair user in space. |