| Launch No. | Date | Vehicle | Apogee | Passengers | Outcome | Notes |
| 0 | October 19, 2012 | N/A RSS Jules Verne | 0 km (0 mi) | —N/a | Success | Pad abort test of the New Shepard capsule. |
| 1 | April 29, 2015 | NS1 RSS Jules Verne | 93 km (58 mi) | —N/a | Partial success | Capsule recovered, rocket crashed on landing. Blue Origin deemed mission successful. |
| 2 | November 23, 2015 17:21 | NS2 RSS Jules Verne | 100 km (62 mi) | —N/a | Success | Sub-orbital spaceflight and landing. |
| 3 | January 22, 2016 | NS2 RSS Jules Verne | 101 km (63 mi) | —N/a | Success | Sub-orbital spaceflight and landing of a reused rocket. |
| 4 | April 2, 2016 15:18 | NS2 RSS Jules Verne | 103 km (64 mi) | —N/a | Success | Sub-orbital spaceflight and landing of a reused rocket. |
| 5 | June 19, 2016 14:36 | NS2 RSS Jules Verne | 101 km (62 mi) | —N/a | Success | Sub-orbital spaceflight and landing of a reused rocket: the fourth launch and landing of the same rocket. Blue Origin published a live webcast of the takeoff and landing. |
| 6 | October 5, 2016 15:36 | NS2 RSS Jules Verne | Rocket: 93 km (58 mi) Capsule: 7 km (4 mi) | —N/a | Success | Sub-orbital spaceflight and landing of a reused rocket. Successful test of the in-flight abort system. The fifth and final launch and landing of the same rocket (NS2). |
| 7 | December 12, 2017 16:59 | NS3 RSS H. G. Wells | Rocket: 98 km (61 mi) Capsule: 98 km (61 mi) | —N/a | Success | Flight to just under 100 km and landing. The first launch of NS3 and a new Crew Capsule 2 . |
| 8 | April 29, 2018 17:06 | NS3 RSS H. G. Wells | 107 km (66 mi) | —N/a | Success | Sub-orbital spaceflight and landing of a reused rocket. |
| 9 | July 18, 2018 15:11 | NS3 RSS H. G. Wells | 118 km (73 mi) | —N/a | Success | Sub-orbital spaceflight and landing of a reused rocket, with capsule carrying a mannequin. Successful test of the in-flight abort system at high altitude. Flight duration was 11 minutes. |
| 10 | January 23, 2019 14:05 | NS3 RSS H. G. Wells | c. 106 km (66 mi) | —N/a | Success | Sub-orbital flight, delayed from December 18, 2018. Eight NASA research and technology payloads were flown. |
| 11 | May 2, 2019 13:34 | NS3 RSS H. G. Wells | c. 105 km (65 mi) | —N/a | Success | Sub-orbital flight. Maximum Ascent Velocity: 3,568 km/h (2,217 mph), duration: 10 minutes, 10 seconds. Payload: 38 microgravity research payloads (nine sponsored by NASA). |
| 12 | December 11, 2019 17:53 | NS3 RSS H. G. Wells | c. 104 km (64 mi) | —N/a | Success | Sub-orbital flight, Payload: Multiple commercial, research (8 sponsored by NASA) and educational payloads, including postcards from Club for the Future. The sixth launch and landing of the same rocket. |
| 13 | October 13, 2020 13:37 | NS3 RSS H. G. Wells | c. 107 km (66 mi) | —N/a | Success | 7th flight of the same capsule/rocket. Onboard 12 payloads include Space Lab Technologies, Southwest Research Institute, postcards and seeds for Club for the Future, and multiple payloads for NASA including SPLICE to test future lunar landing technologies in support of the Artemis program. |
| 14 | January 14, 2021 16:57 | NS4 RSS First Step | Rocket: 106 km (66 mi) Capsule: 107 km (66 mi) | —N/a | Success | Qualification flight for NS4 rocket and capsule and maiden flight for NS4 |
| 15 | April 14, 2021 16:51 | NS4 RSS First Step | Rocket: 106 km (66 mi) Capsule: 107 km (66 mi) | —N/a | Success | Second flight of NS4, first preflight human passenger process test where Blue Origin conducted an "Astronaut Rehearsal". Gary Lai, Susan Knapp, Clay Mowry, and Audrey Powers, all Blue Origin personnel, were "stand-in astronauts". Lai and Powers briefly entered the capsule during the test. |
| 16 | July 20, 2021 13:12 | NS4 RSS First Step | Rocket: 105 km (65 mi) Capsule: 107 km (66 mi) | Jeff Bezos Mark Bezos Wally Funk Oliver Daemen | Success | First flight of New Shepard with passengers. |
| 17 | August 25, 2021 14:31 | NS3 RSS H. G. Wells | Rocket: 105 km (65 mi) Capsule: 105 km (65 mi) | —N/a | Success | Payload mission consisting of 18 commercial payloads inside the capsule, a NASA lunar landing technology demonstration installed on the exterior of the rocket and an art installation installed on the exterior of the capsule. |
| 18 | October 13, 2021 14:49 | NS4 RSS First Step | Rocket: 106 km (66 mi) Capsule: 107 km (66 mi) | Chris Boshuizen Glen de Vries William Shatner Audrey Powers | Success | |
| 19 | December 11, 2021 10:50 | NS4 RSS First Step | Rocket: 106 km (66 mi) Capsule: 107 km (66 mi) | Lane Bess Cameron Bess Evan Dick Laura Shepard Churchley Michael Strahan Dylan Taylor | Success | |
| 20 | March 31, 2022 13:57 | NS4 RSS First Step | Rocket: 107 km (66 mi) Capsule: 107 km (66 mi) | Marty Allen Sharon Hagle Marc Hagle Jim Kitchen George Nield Gary Lai | Success | |
| 21 | June 4, 2022 13:25 | NS4 RSS First Step | Rocket: 106 km (66 mi) Capsule: 107 km (66 mi) | Evan Dick Katya Echazarreta Hamish Harding Victor Correa Hespanha Jaison Robinson Victor Vescovo | Success | |
| 22 | August 4, 2022 13:56 | NS4 RSS First Step | Rocket: 106 km (66 mi) Capsule: 107 km (66 mi) | Coby Cotton Mário Ferreira Vanessa O'Brien Clint Kelly III Sara Sabry Steve Young | Success | |
| 23 | September 12, 2022 14:27 | NS3 RSS H. G. Wells | 11 km (7 mi) | —N/a | Failure | Research mission with 36 commercial payloads on board including two on the exterior of the rocket. The spacecraft's launch escape system activated after the rocket's BE-3 main engine failed around a minute after liftoff leading to a loss of control. The capsule was safely recovered whilst the rocket was lost as it impacted on ground. |
| 24 | December 1, 2023 16:43 | NS4 RSS H. G. Wells | Rocket: 106 km (66 mi) Capsule: 107 km (66 mi) | —N/a | Success | Successful Return to Flight mission following failure of NS-23 more than a year prior. 33 payloads and 38,000 Club for the Future postcards from students around the world. |
| 25 | May 19, 2024 13:30 | NS4 RSS First Step | c. 106 km | Kenneth Hess Sylvain Chiron Mason Angel Ed Dwight Carol Schaller Gopi Thotakura | Success | |
| 26 | August 29, 2024 13:07 | NS4 RSS First Step | Capsule: 105 km (65 mi) | Ephraim Rabin Nicolina Elrick Eugene Grin Rob Ferl Karsen Kitchen Eiman Jahangir | Success | |
| 27 | October 23, 2024 15:27 | NS5 RSS Kármán Line | Capsule: 101 km (63 mi) | —N/a | Success | First flight of Propulsion Module NS5 and capsule RSS Kármán Line. 12 payloads and tens of thousands of Club for the Future postcards. |
| 28 | November 22, 2024 15:30 | NS4 RSS First Step | Capsule 107 km (66 mi) | Emily Calandrelli Sharon Hagle Marc Hagle Austin Litteral James "J ." Russell Henry Wolfond | Success | |
| 29 | February 4, 2025 16:00 | NS5 RSS H. G. Wells | Rocket: 105 km (65 mi) Capsule: 105 km (65 mi) | —N/a | Success | Research mission on behalf of NASA, simulated lunar gravity by spinning the capsule at 11 rpm using the spacecraft's reaction control system. 30 payloads, 29 internal and one external. |
| 30 | February 25, 2025 15:49 | NS4 RSS First Step | Rocket: 106 km (66 mi) Capsule: 106 km (66 mi) | Lane Bess Jesús Calleja Tushar Shah Richard Scott Elaine Chia Hyde Russell Wilson | Success | |
| 31 | April 14, 2025 13:30 | NS5 RSS Kármán Line | Rocket: 106 km (66 mi) Capsule: 106 km (66 mi) | Aisha Bowe Amanda Nguyen Gayle King Katy Perry Kerianne Flynn Lauren Sánchez | Success | First spaceflight with an all-female crew since Vostok 6 in 1963. |
| 32 | May 31, 2025 13:39 | NS4 RSS First Step | Rocket: 104 km (65 mi) Capsule: 104 km (65 mi) | Aymette Medina Jorge Gretchen Green Jaime Alemán Jesse Williams Mark Rocket Paul Jeris | Success | |
| 33 | June 29, 2025 14:40 | NS5 RSS Kármán Line | Rocket: 106 km (66 mi) Capsule: 106 km (66 mi) | Allie Kuehner Carl Kuehner Leland Larson Freddie Rescigno, Jr. Owolabi Salis James Sitkins | Success | |
| 34 | August 3, 2025 12:42 | NS4 RSS First Step | Rocket: 106 km (66 mi) Capsule: 106 km (66 mi) | Arvi Bahal Gökhan Erdem Deborah Martorell Lionel Pitchford J. D. Russell Justin Sun | Success | |
| 35 | September 18, 2025 13:00 | NS5 RSS H. G. Wells | Rocket: 105 km (65 mi) Capsule: 105 km (65 mi) | —N/a | Success | Uncrewed flight that flew more than 40 scientific and research payloads to space and back. These payloads include 24 experiments from NASA’s TechRise Student Challenge, and payloads for Johns Hopkins Applied Physics Laboratory, University, College, Teledyne, Space Lab Technologies, and Teachers in Space, among others. Final flight for RSS H. G. We |
| 36 | October 8, 2025 13:40 | NS4 RSS First Step | Rocket: 106 km (66 mi) Capsule: 106 km (66 mi) | Jeff Elgin Danna Karagussova Clint Kelly III Aaron Newman Vitalii Ostrovsky William H. Lewis | Success | |
| 37 | December 20, 2025 14:15 | NS5 RSS Karman Line | Rocket: 106 km (66 mi) Capsule: 106 km (66 mi) | Michaela Benthaus Joey Hyde Hans Koenigsmann Neal Milch Adonis Pouroulis Jason Stansell | Success | First flight to carry a wheelchair user into space, with Benthaus onboard. |
| 38 | January 22, 2026 16:25 | NS4 RSS First Step | Rocket: 106 km (66 mi) Capsule: 106 km (66 mi) | Tim Drexler Linda Edwards Alain Fernandez Alberto Gutiérrez Jim Hendren Laura Stiles | Success | Originally planned to fly with Andrew Yaffe onboard, who was replaced by Stiles due to illness. |
