| Year | Title | Role | Notes |
| 2002–2003 | Firefly | Inara Serra | Main role |
| 2003–2004 | Still Life | Maggie Jones | Main role (season 1) |
| 2005 | It's Always Sunny in Philadelphia | Carmen | Episode: "It's Always Sunny on TV" (unaired pilot) |
| 2005–2006 | Justice League Unlimited | Dinah Lance / Black Canary | Voice, recurring role |
| 2006 | The O.C. | Maya Griffin | Guest role (season 3) |
| How I Met Your Mother | Chloe | Episode: "Swarley" |
| Justice | Lisa Cruz | Episode: "Christmas Party" |
| Kitchen Confidential | Gia | Episode: "An Affair to Remember" |
| 2006–2007 | Stargate SG-1 | Adria | Guest role (season 10) |
| 2007 | Las Vegas | Sara Samari | Episode: "The Burning Bedouin" |
| Heartland | Nurse Jessica Kivala | Guest role (season 1) |
| Sands of Oblivion | Alice Carter | Television film |
| 2008 | Dirt | Claire Leland | Episode: "And the Winner Is" |
| Numb3rs | Lynn Potter | Episode: "Blowback" |
| 2009 | Medium | Brooke Hoyt | Episode: "All in the Family" |
| 2009–2011 | V | Anna | Main role (seasons 1–2) |
| 2010 | The Deep End | Beth Bancroft | Unaired TV pilot |
| 2011 | Batman: The Brave and the Bold | Cheetah | Voice, episode: "Triumvirate of Terror!" |
| Look Again | Allison | Television film |
| 2011–2013 | Homeland | Jessica Brody | Main role (seasons 1–3) |
| 2011–2014 | The Mentalist | Erica Flynn | Guest role (seasons 3–4, 7) |
| 2012–2013 | The Good Wife | Isobel Swift | 2 episodes |
| 2014 | Warriors | Tory | Unsold TV pilot |
| The Red Tent | Rachel | Miniseries |
| 2014–2023 | The Flash | Gideon | Voice, 34 episodes (uncredited) |
| 2015–2019 | Gotham | Leslie Thompkins | Recurring role (season 1); main role (seasons 2–5) |
| 2019 | A Series of Unfortunate Events | Beatrice Baudelaire | 2 episodes |
| Sessão de Terapia | Dr. Sofia Callas | Guest role (season 4), 9 episodes |
| 2020 | The Twilight Zone | Michelle Weaver / Phineas Lowell | Episode: "Downtime" |
| 2021 | Home Invasion | Casie | Main role |
| 2022 | Beat Bobby Flay | Herself | Guest host; episode: "Morena and the Marcona" |
| The Endgame | Elena Federova | Main role |
| 2024–2025 | Fire Country | Mickey Fox | Guest role 2 episodes |
| 2025–present | Sheriff Country | Mickey Fox | Main role |
