| Year | Title | Role | Notes |
| 2011–2024 | The Game Theorists | Himself | 533 episodes |
| 2015 | How to Beat a Monkey at Chess | Music video by Random Encounters |
| Mangled | Music video by NateWantsToBattle |
| LORE in a Minute! | Episode: "LORE: Dragon Ball Z Lore in a Minute!" |
| 2015–2020 | The Completionist | 3 episodes |
| 2015–2024 | The Film Theorists | 425 episodes |
| 2016 | FNAF the Musical | Phone Guy/William Afton | Music video by Random Encounters |
| MatPat's Game Lab | Himself | YouTube Original; main role |
| CaptainSparklez | Episode: "HELIUM RAP BATTLE VS MATPAT" |
| Scare PewDiePie | YouTube Original; 2 episodes |
| 2017 | Death Battle | Keith | Voice role; "Power Rangers (Megazord) VS Voltron" |
| NERDY NUMMIES | Himself | Episode: "NINTENDO SWITCH COOKIES ft. MatPat!" |
| GUMMY FOOD vs REAL FOOD! | 2 episodes |
| Transformers: Titans Return | Computron | Voice role |
| Bendy and the Ink Musical | Bendy | Voice role; Music video by Random Encounters |
| Sonic Forces Academy | Himself | |
| 2018 | Cuphead the Musical | Dr. Kahl, Wally Warbles, Willy Warbles | Voice role; Music video by Random Encounters |
| Food Court | Himself | YouTube Original; Episode: "Food Court ft. MatPat" |
| Transformers: Power of the Primes | Swoop | Voice role |
| The FNaF Show | Himself | Episode: Season 2 – Episode 4 ft. MatPat |
| 2018–2019 | Escape the Night | The detective | 14 episodes |
| 2019 | A Heist with Markiplier | Hermit | |
| FNAF the Musical: Web of Lies | Phone Guy/William Afton | Music video by Random Encounters |
| 2019–2023 | Pitch Meeting | Himself | 2 episodes |
| 2020 | What's Your Favorite Scary Movie? | Episode: "MatPat on THE BLAIR WITCH PROJECT!" |
| 2020–2024 | The Food Theorists | 188 episodes |
| 2021 | Instant Influencer with ZHC | YouTube Original; Episode: "Best Giant Art Wins $100,000" |
| Bendy and the Wolf | Bendy | Voice role; Music video by Random Encounters |
| Hero Mode | Himself | |
| Disco Giraffe and Biker Jellyfish | | 1 episode |
| Big Change | Himself | Episode: "MatPat's Secret To Working From Home" |
| Dad | 3 episodes |
| 2021–2022 | FootofaFerret | Voice role; 2 episodes |
| 2022 | Markiplier | Episode: "PowerWash Pals: MatPat from Game Theory" |
| In Space with Markiplier | Theory crew (in Part 1) | |
| Mack (in Part 2) | |
| 2023 | Five Nights at Freddy's | Ness | Credited as Sparky's Diner waiter; reference to episode of Game Theory: "Undertale – Sans's SECRET Identity!" |
| 2023–2024 | The Style Theorists | Himself | 46 episodes |
| 2024 | The Kill Count | Episode: "Five Nights at Freddy's (2023) KILL COUNT" |
| WIRED Autocomplete Interview | Episode: "MatPat Answers the Web's Most Searched Questions | WIRED" |
| Last Meal | Episode: "MatPat Eats His Last Meal" |
| We Surprised MatPat With His Own Movie | |
| FNAF the Musical: Dark Remains | Phone Guy/William Afton | Music video by Random Encounters |
| FNAF the Musical: Shadows of Agony |
| MrBeast | Himself | Episode: "50 YouTubers Fight for $1,000,000" |
| FNAF UNSOLVED | Episode: "MIDNIGHT MOTORIST" |
| The Entire FNAF Timeline | Fredbear's Family Diner announcer | Voice role |
| 2025 | Five Nights at Freddy's 2 | Toy Bonnie | Voice role |
