| Year | Title | Peak chart positions | Record Label | B-sideFrom same album as A-side except where indicated | Album |
| US BB | US CB | US AC | US R&B | UK | CAN(CHUM)(RPM) | AUS |
| 1962 | "The Gypsy Cried" | 24 | 18 | — | — | — | 3 | — | Roulette Records | "Red Sails in the Sunset" (Non-LP track) | Lou Christie |
| 1963 | "Two Faces Have I" | 6 | 3 | — | 11 | — | 3 | 20 | "All That Glitters Isn't Gold" |
| "How Many Teardrops" | 46 | 41 | — | — | — | 23 | 79 | "You and I (Have a Right to Cry)"(No. 119 US CB) |
| "Shy Boy" | 119 | 135 | — | — | — | — | — | "It Can Happen" | Non-LP tracks |
| 1964 | "Stay" | — | — | — | — | — | — | — | "There They Go" (Non-LP track) | Lou Christie |
| "Guitars and Bongos" | 123 | 131 | — | — | — | 44 | — | Colpix Records | "Merry-Go-Round" (Non-LP track) | Lou Christie Strikes Again |
| "Have I Sinned" | — | — | — | — | — | — | — | "Pot of Gold" |
| 1965 | "Why Did You Do It Baby" | — | — | — | — | — | — | — | "Make Summer Last Forever" |
| "A Teenager in Love" | — | — | — | — | — | — | — | "Back Track" |
| "Lightnin' Strikes" | 1 | 1 | — | — | 11 | 1 | 9 | MGM Records | "Cryin' in the Streets" | Lightnin' Strikes |
| 1966 | "Outside the Gates of Heaven" | 45 | 59 | — | — | — | 32 | — | Co & Ce Records | "All That Glitters Isn't Gold" | Non-LP tracks |
| "Big Time" | 95 | — | — | — | — | — | — | Colpix Records | "Cryin' on My Knees" | Lou Christie Strikes Again |
| "Rhapsody in the Rain" | 16 | 20 | — | — | 37 | 10 | 40 | MGM Records | "Trapeze" (from Lightning Strikes) | Painter of Hits |
| "Painter" | 81 | 77 | — | — | — | 60 | — | "Du Ronda" |
| "If My Car Could Only Talk" | 118 | — | — | — | — | — | — | "Song of Lita" | Non-LP tracks |
| "Since I Don't Have You" | 118 | 101 | — | — | — | 71 | — | "Wild Life's in Season" | Painter of Hits |
| 1967 | "Shake Hands and Walk Away Cryin | 95 | — | — | — | — | — | — | Columbia Records | "Escape" | Non-LP tracks |
| "Self Expression (The Kids on the Street Will Never Give In)" | — | 127 | — | — | — | — | — | "Back to the Days of the Romans" |
| "I Remember Gina" | — | 139 | — | — | — | — | — | "Escape" |
| "Don't Stop Me (Jump Off the Edge of Love)" | — | — | — | — | — | — | — | "Back to the Days of the Romans" |
| 1968 | "Genesis and the Third Verse" | — | — | — | — | — | — | — | Buddah Records | "Rake Up the Leaves" |
| "Canterbury Road" | — | — | — | — | — | — | — | "Saints of Aquarius" |
| 1969 | "I'm Gonna Make You Mine" | 10 | 7 | — | — | 2 | 5 | 28 | "I'm Gonna Get Married" | I'm Gonna Make You Mine |
| "Are You Getting Any Sunshine?" | 73 | 84 | — | — | — | 56 | — | "It'll Take Time" |
| 1970 | "Love Is Over" | — | — | — | — | — | — | — | "She Sold Me Magic" (from I'm Gonna Make You Mine) (No. 25 UK) (No. 1 JP) | Non-LP tracks |
| "Indian Lady" | 106 | 75 | 39 | — | — | — | 89 | "Glory River" |
| 1971 | "Lighthouse" | — | — | — | — | — | — | — | Three Brothers Records | "Waco" | Paint America Love |
| 1972 | "Sing Me, Sing Me" | — | — | — | — | — | — | — | "Paper Song" |
| 1973 | "Blue Canadian Rocky Dream" | — | 102 | — | — | — | — | — | "Wilma Lee and Stoney" | Lou Christie |
| 1974 | "Beyond the Blue Horizon" | 80 | 72 | 12 | — | — | 57 | — | "Saddle the Wind" |
| 1974 | "Good Mornin'/Zip-a-Dee-Doo-Dah" | — | — | — | — | — | — | — | "You Were the One" |
| 1975 | "Summer Days" | — | 120 | — | — | — | — | — | Slipped Disc Records | "The One and Only Original Sunshine Kid" | Non-LP tracks |
| 1976 | "Riding in My Van" | — | — | — | — | — | — | — | Epic Records | "Summer in Malibu" |
| "You're Gonna Make Love to Me" | — | — | — | — | — | — | — | Midland International Records | "Fantasies" |
| 1977 | "Spanish Wine" | — | 95 | — | — | — | — | — | "Dancing in the Sand" |
| 1986 | Lou Christie/Lesley Gore "Since I Don't Have You"/"It's Only Make Believe" | — | — | — | — | — | — | — | Manhattan Records | "Our Love Was Meant To Be" |
| 1990 | Lou Christie/Pia Zadora "Don't Knock My Love" (shortVersion) | — | — | — | — | — | — | — | Midsong Records | "Don't Knock My Love" (LongVersion) |