| Party | Abbr. | Founded | Position | Ideology | Leader | Representation |
| Senators | Deputies |
| | | National Action PartyPartido Acción Nacional | PAN | 1939 | Centre-right to right-wing | mw- Liberal conservatismChristian democracyEconomic liberalism | Jorge Romero Herrera | 21 / 128 | 70 / 500 |
| | | Institutional Revolutionary PartyPartido Revolucionario Institucional | PRI | 1929 (PNR) 1938 (PRM) 1946 (PRI) | Centre to centre-right | ConstitutionalismSocial democracyBig tent | Alejandro Moreno Cárdenas | 13 / 128 | 37 / 500 |
| | | Ecologist Green Party of MexicoPartido Verde Ecologista de México | PVEM | 1986 (PVM) 1991 (PEM) 1993 (PVEM) | Centre-left | Green politics | Karen Castrejón Trujillo | 14 / 128 | 62 / 500 |
| | | Labor PartyPartido del Trabajo | PT | 1990 | Left-wing | Democratic socialismLaborismLeft-wing nationalism | Alberto Anaya | 6 / 128 | 49 / 500 |
| | | Citizens' MovementMovimiento Ciudadano | MC | 1999 (CpD) 2002 (CON) 2011 (MC) | Centre-left | Social democracyParticipatory democracyProgressivism | Jorge Máynez | 6 / 128 | 28 / 500 |
| | | National Regeneration MovementMovimiento Regeneración Nacional | Morena | 2014 | Left-wing | Anti-neoliberalismAlter-globalizationLeft-wing populismLeft-wing nationalism | Luisa María Alcalde Luján | 67 / 128 | 253 / 500 |