| No. | Portrait | Name (Birth–Death) | Term of office | Political party | Vice President | Notes |
| Took office | Left office | Tenure |
| 1 | | Guadalupe Victoria (1786–1843) | 10 October 1824 | 31 March 1829 | 4 years, 172 days | Independent (affiliated with the Liberal Party) | Nicolás Bravo (1824–1827) | First constitutionally elected President of Mexico, and the only President who completed his full term in almost 30 years of independent Mexico. |
| 2 | | Vicente Guerrero (1782–1831) | 1 April 1829 | 17 December 1829 | 260 days | Liberal Party | Anastasio Bustamante | He was appointed by Congress after the "resignation" of president-elect Manuel Gómez Pedraza. |
| 3 | | José María Bocanegra (1787–1862) | 17 December 1829 | 23 December 1829 | 6 days | Popular York Rite Party (part of the Liberal Party) | Anastasio Bustamante | He was appointed Interim President by Congress when Guerrero left office to fight the rebellion of his conservative Vice President Bustamante. |
| | | Vélez–Quintanar–Alamán (Triumvirate) | 23 December 1829 | 31 December 1829 | 8 days | Liberal Party (Vélez) Independent (Quintanar and Alamán) | Anastasio Bustamante | Pedro Vélez president of the Supreme Court, he was appointed by the Council of Government as head of the executive triumvirate along with Lucas Alamán and Luis Quintanar. |
| 4 | | Anastasio Bustamante (1780–1853) | 1 January 1830 | 13 August 1832 | 2 years, 225 days | Conservative Party | Himself | As Vice President he assumed the presidency after the conservative coup against Guerrero. |
| 5 | | Melchor Múzquiz (1788–1844) | 14 August 1832 | 24 December 1832 | 132 days | Popular York Rite Party (part of the Liberal Party) | Anastasio Bustamante | He was appointed Interim President by Congress when Bustamante left office to fight the rebellion of Santa Anna. |
| 6 | | Manuel Gómez Pedraza (1789–1851) | 24 December 1832 | 31 March 1833 | 97 days | Federalist York Rite Party (part of the Liberal Party) | Vacant | He assumed the presidency to conclude the term he would have begun in 1829, had he not "resigned" prior to inauguration, as the winner of the elections of 1828. |
| 7 | | Valentín Gómez Farías (1781–1858) | 1 April 1833 | 16 May 1833 | 45 days | Liberal Party | Himself | As Vice President he assumed the presidency in place of Santa Anna, along with whom he was elected in the elections of 1833. |
| 8 | | Antonio López de Santa Anna (1794–1876) | 16 May 1833 | 3 June 1833 | 18 days | Liberal Party | Valentín Gómez Farías | He assumed the presidency as the constitutionally-elected president. He alternated in the presidency with Vice President Gómez Farías four more times until 24 April 1834. |
| (7) | | Valentín Gómez Farías (1781–1858) | 3 June 1833 | 18 June 1833 | 15 days | Liberal Party | Himself | |
| (8) | | Antonio López de Santa Anna (1794–1876) | 18 June 1833 | 5 July 1833 | 17 days | Liberal Party | Valentín Gómez Farías | |
| (7) | | Valentín Gómez Farías (1781–1858) | 5 July 1833 | 27 October 1833 | 114 days | Liberal Party | Himself | |
| (8) | | Antonio López de Santa Anna (1794–1876) | 27 October 1833 | 15 December 1833 | 49 days | Liberal Party | Valentín Gómez Farías | |
| (7) | | Valentín Gómez Farías (1781–1858) | 16 December 1833 | 24 April 1834 | 129 days | Liberal Party | Himself | He promoted several liberal reforms that led to the discontent of conservatives and the church. Santa Anna took office again aligned with conservatives; Gómez Farías went into exile. |
| (8) | | Antonio López de Santa Anna (1794–1876) | 24 April 1834 | 27 January 1835 | 278 days | Conservative Party | Valentín Gómez Farías | He cancelled the liberal reforms. On 27 January, the Sixth Constituent Congress dismissed Gómez Farías as Vice President. |
| 9 | | Miguel Barragán (1789–1836) | 28 January 1835 | 27 February 1836 | 1 year, 30 days | Conservative Party | Vacant | He was appointed Interim President by Congress when Santa Anna left office to fight the rebellion of Zacatecas. On 23 October, Congress enacted the Constitutional Basis, which voided the Constitution of 1824 and the federal system. He served both as the last president of the First Federal Republic and the first of the Centralist Republic. |
