| State | Portrait | Senator | Party | Born | Occupation(s) | Previous elective office(s) | Education | Assumed office | Class | Residence |
| Alabama | | Tommy Tuberville | | Republican | (1954-09-18) September 18, 1954 | Investment management firm partner College football coach | None | Southern Arkansas University (BS) | January 3, 2021 | 2026 Class 2 | Auburn |
| | Katie Britt | | Republican | (1982-02-02) February 2, 1982 | Alabama Wildlife Federation Board Member Business Council of Alabama President and CEO Campaign manager Lawyer University administrator Senate staffer | None | University of Alabama (BS, JD) | January 3, 2023 | 2028 Class 3 | Montgomery |
| Alaska | | Lisa Murkowski | | Republican | (1957-05-22) May 22, 1957 | Lawyer | Alaska House of Representatives | Georgetown University (AB)Willamette University (JD) | December 20, 2002 | 2028 Class 3 | Girdwood |
| | Dan Sullivan | | Republican | (1964-11-13) November 13, 1964 | Assistant Secretary of State for Economic and Business Affairs Lawyer U . Marine Corps officer | Alaska Attorney General | Harvard University (AB)Georgetown University (MS, JD) | January 3, 2015 | 2026 Class 2 | Anchorage |
| Arizona | | Mark Kelly | | Democratic | (1964-02-21) February 21, 1964 | Giffords Law Center to Prevent Gun Violence Co-founder NASA astronaut U . Navy officer | None | United States Merchant Marine Academy (BS)Naval Postgraduate School (MS) | December 2, 2020 | 2028 Class 3 | Tucson |
| | Ruben Gallego | | Democratic | (1979-11-20) November 20, 1979 | Political strategist Public relations project manager Chief of Staff to Phoenix City Councilman U . Marine Corps | U . House Arizona House | Harvard University (BA) | January 3, 2025 | 2030 Class 1 | Phoenix |
| Arkansas | | John Boozman | | Republican | (1950-12-10) December 10, 1950 | Optometrist | U . House Rogers Public Schools Board | University of ArkansasSouthern College of Optometry (OD) | January 3, 2011 | 2028 Class 3 | Rogers |
| | Tom Cotton | | Republican | (1977-05-13) May 13, 1977 | Lawyer United States Army officer | U . House | Harvard University (AB, JD) | January 3, 2015 | 2026 Class 2 | Little Rock |
| California | | Alex Padilla | | Democratic | (1973-03-22) March 22, 1973 | Engineer | Secretary of State of California California Senate Los Angeles City Council President | Massachusetts Institute of Technology (BS) | January 20, 2021 | 2028 Class 3 | Los Angeles |
| | Adam Schiff | | Democratic | (1960-06-22) June 22, 1960 | Assistant Prosecutor for the United States Attorney for the Southern District of California Lawyer | U . House California Senate | Stanford University (BA)Harvard University (JD) | December 8, 2024 | 2030 Class 1 | Burbank |
| Colorado | | Michael Bennet | | Democratic | (1964-11-28) November 28, 1964 | Chief of staff to the Mayor of Denver Denver Public Schools Superintendent Investment company executive Lawyer | None | Wesleyan University (BA)Yale University (JD) | January 21, 2009 | 2028 Class 3 | Denver |
| | John Hickenlooper | | Democratic | (1952-02-07) February 7, 1952 | Businessman Geologist | Governor of Colorado Mayor of Denver | Wesleyan University (BA, MS) | January 3, 2021 | 2026 Class 2 | Denver |
| Connecticut | | Richard Blumenthal | | Democratic | (1946-02-13) February 13, 1946 | U . Attorney Lawyer Senate staffer Marine Corps Reserve Sergeant | Connecticut Attorney General Connecticut Senate Connecticut House of Representatives | Harvard University (AB)Trinity College, CambridgeYale University (JD) | January 3, 2011 | 2028 Class 3 | Greenwich |
| | Chris Murphy | | Democratic | (1973-08-03) August 3, 1973 | Political campaign manager Lawyer | U . House Connecticut Senate Connecticut House of Representatives | Williams College (BA)Exeter College, OxfordUniversity of Connecticut (JD) | January 3, 2013 | 2030 Class 1 | Hartford |
| Delaware | | Chris Coons | | Democratic | (1963-09-09) September 9, 1963 | Nonprofit organization executive Lawyer | New Castle County Executive New Castle County Council | Amherst College (BA)Yale University (MAR, JD) | November 15, 2010 | 2026 Class 2 | Wilmington |
| | Lisa Blunt Rochester | | Democratic | (1962-02-10) February 10, 1962 | Nonprofit executive Consultant Delaware Personnel Director Delaware Secretary of Labor Delaware Deputy Secretary of Health and Social Services | U . House | Villanova UniversityFairleigh Dickinson University (BA)University of Delaware (MA) | January 3, 2025 | 2030 Class 1 | Wilmington |
| Florida | | Rick Scott | | Republican | (1952-12-01) December 1, 1952 | Venture capitalist Columbia/HCA CEO Lawyer U . Navy | Governor of Florida | University of Missouri-Kansas City (BS)Southern Methodist University (JD) | January 8, 2019 | 2030 Class 1 | Naples |
| | Ashley Moody | | Republican | (1975-03-28) March 28, 1975 | Assistant U . attorney for the Middle District of Florida Student representative on the Board of Regents Professor Lawyer | Florida Attorney General Judge of the Thirteenth Judicial Circuit Court of Florida | University of Florida (BS, MS, JD)Stetson University (LLM) | January 21, 2025 | 2026 Class 3 | Tampa |
| Georgia | | Jon Ossoff | | Democratic | (1987-02-16) February 16, 1987 | Investigative journalist Documentary film producer U . House staffer | None | Georgetown University (BS)London School of Economics (MSc) | January 20, 2021 | 2026 Class 2 | Atlanta |
| | Raphael Warnock | | Democratic | (1969-07-23) July 23, 1969 | Pastor | None | Morehouse College (BA)Union Theological Seminary (MDiv, MPhil, PhD) | January 20, 2021 | 2028 Class 3 | Atlanta |
| Hawaii | | Brian Schatz | | Democratic | (1972-10-20) October 20, 1972 | Nonprofit organization executive Teacher | Lieutenant Governor of Hawaii Hawaii House of Representatives | Pomona College (BA) | December 26, 2012 | 2028 Class 3 | Honolulu |
| | Mazie Hirono | | Democratic | (1947-11-03) November 3, 1947 | Lawyer | U . House Lieutenant Governor of Hawaii Hawaii House of Representatives | University of Hawaii at Manoa (BA)Georgetown University (JD) | January 3, 2013 | 2030 Class 1 | Honolulu |
| Idaho | | Mike Crapo | | Republican | (1951-05-20) May 20, 1951 | Lawyer | U . House Idaho Senate | Brigham Young University (BA)Harvard University (JD) | January 3, 1999 | 2028 Class 3 | Idaho Falls |
| | Jim Risch | | Republican | (1943-05-03) May 3, 1943 | Nonprofit organization executive Professor Lawyer Rancher | Governor of Idaho Lieutenant Governor of Idaho Idaho Senate President pro tempore Ada County Prosecuting Attorney | University of Wisconsin-MilwaukeeUniversity of Idaho (BS, JD) | January 3, 2009 | 2026 Class 2 | Boise |
| Illinois | | Dick Durbin | | Democratic | (1944-11-21) November 21, 1944 | Professor Lawyer | U . House | Georgetown University (BS, JD) | January 3, 1997 | 2026 Class 2 | Springfield |
| | Tammy Duckworth | | Democratic | (1968-03-12) March 12, 1968 | Illinois Director of Veterans Affairs U . Assistant Secretary of Veterans Affairs Center for Nursing Research at Northern Illinois University Coordinator Army National Guard officer | U . House | University of Hawaiʻi–Mānoa (BA)George Washington University (MA)Northern Illinois UniversityCapella University (PhD) | January 3, 2017 | 2028 Class 3 | Hoffman Estates |
| Indiana | | Todd Young | | Republican | (1972-08-24) August 24, 1972 | Management consultant Professor Lawyer U . Marine Corps officer | U . House | United States Naval Academy (BS)University of Chicago (MBA)University of London (MA)Indiana University, Indianapolis (JD) | January 3, 2017 | 2028 Class 3 | Bargersville |
| | Jim Banks | | Republican | (1979-07-16) July 16, 1979 | Real estate broker U . Navy Reserve Business development director Campaign manager U . House staffer | U . House Indiana Senate | Indiana University Bloomington (BA)Grace College & Seminary (MBA) | January 3, 2025 | 2030 Class 1 | Columbia City |
| Iowa | | Chuck Grassley | | Republican | (1933-09-17) September 17, 1933 | College professor Farmer | U . House Iowa House of Representatives | University of Northern Iowa (BA, MA)University of Iowa | January 3, 1981 | 2028 Class 3 | New Hartford |
| | Joni Ernst | | Republican | (1970-07-01) July 1, 1970 | Army National Guard officer Farmer | Iowa Senate Montgomery County Auditor | Iowa State University (BA)Columbus State University (MPA) | January 3, 2015 | 2026 Class 2 | Red Oak |
| Kansas | | Jerry Moran | | Republican | (1954-05-29) May 29, 1954 | Lawyer Banker | U . House Kansas Senate | Fort Hays State UniversityUniversity of Kansas (BA, JD) | January 3, 2011 | 2028 Class 3 | Manhattan |
| | Roger Marshall | | Republican | (1960-08-09) August 9, 1960 | Doctor U . Army Reserve officer | U . House | Kansas State University (BS)University of Kansas (MD) | January 3, 2021 | 2026 Class 2 | Great Bend |
| Kentucky | | Mitch McConnell | | Republican | (1942-02-20) February 20, 1942 | Assistant Attorney General for the U . Department of Justice Office of Legislative Affairs U . Senate staff member Lawyer | Jefferson County Judge/Executive | University of Louisville (BA)University of Kentucky (JD) | January 3, 1985 | 2026 Class 2 | Louisville |
| | Rand Paul | | Republican | (1963-01-07) January 7, 1963 | Physician specializing in Ophthalmology | None | Baylor UniversityDuke University (MD) | January 3, 2011 | 2028 Class 3 | Bowling Green |
| Louisiana | | Bill Cassidy | | Republican | (1957-09-28) September 28, 1957 | Physician | U . House Louisiana Senate | Louisiana State University (BS, MD) | January 3, 2015 | 2026 Class 2 | Baton Rouge |
| | John Kennedy | | Republican | (1951-11-21) November 21, 1951 | Secretary of the Louisiana Department of Revenue Staff of Louisiana Governor Buddy Roemer Professor Lawyer | Louisiana Treasurer | Vanderbilt University (BA)University of Virginia (JD)Magdalen College, Oxford (BCL) | January 3, 2017 | 2028 Class 3 | Madisonville |
| Maine | | Susan Collins | | Republican | (1952-12-07) December 7, 1952 | Deputy Treasurer of Massachusetts Small Business Administration Regional Director Senate staffer House staffer | None | St. Lawrence University (BA) | January 3, 1997 | 2026 Class 2 | Bangor |
| | Angus King | | Independent | (1944-03-31) March 31, 1944 | Corporate executive Entrepreneur Public television news program host Senate staffer Lawyer | Governor of Maine | Dartmouth College (BA)University of Virginia (JD) | January 3, 2013 | 2030 Class 1 | Brunswick |
| Maryland | | Chris Van Hollen | | Democratic | (1959-01-10) January 10, 1959 | Maryland Governor's legislative advisor U . Senate staff member Lawyer | U . House Maryland Senate Maryland House of Delegates | Swarthmore College (BA)Harvard University (MPP)Georgetown University (JD) | January 3, 2017 | 2028 Class 3 | Kensington |
| | Angela Alsobrooks | | Democratic | (1971-02-23) February 23, 1971 | Executive Director of the Prince George's County Revenue Authority Education liaison to the Prince George's County Executive Assistant Prince George's State's Attorney | Prince George's County Executive Prince George's State's Attorney | Duke University (BA)University of Maryland, Baltimore (JD) | January 3, 2025 | 2030 Class 1 | Upper Marlboro |
| Massachusetts | | Elizabeth Warren | | Democratic | (1949-06-22) June 22, 1949 | CFPB Special Advisor COP Chair Nonprofit organization executive Research associate Professor Lawyer | None | George Washington UniversityUniversity of Houston (BS)Rutgers University (JD) | January 3, 2013 | 2030 Class 1 | Cambridge |
| | Ed Markey | | Democratic | (1946-07-11) July 11, 1946 | Lawyer United States Army Reserve | U . House Massachusetts House of Representatives | Boston College (BA, JD) | July 16, 2013 | 2026 Class 2 | Malden |
| Michigan | | Gary Peters | | Democratic | (1958-12-01) December 1, 1958 | College professor and lecturer Lawyer Financial advisor U . Navy Reserve Officer | U . House Michigan Senate | Alma College (BA)University of Detroit (MBA)Wayne State University (JD, MA)Michigan State University (MA) | January 3, 2015 | 2026 Class 2 | Bloomfield Hills |
| | Elissa Slotkin | | Democratic | (1976-07-10) July 10, 1976 | Consultant Assistant Secretary of Defense for International Security Affairs CIA analyst Department of State political affairs officer | U . House | Cornell University (BA)Columbia University (MIA) | January 3, 2025 | 2030 Class 1 | Holly |
| Minnesota | | Amy Klobuchar | | Democratic (DFL) | (1960-05-25) May 25, 1960 | Lawyer | Hennepin County, Minnesota County Attorney | Yale University (BA)University of Chicago (JD) | January 3, 2007 | 2030 Class 1 | Minneapolis |
| | Tina Smith | | Democratic (DFL) | (1958-03-04) March 4, 1958 | Chief of staff to the Governor of Minnesota Chief of staff to the Mayor of Minneapolis Political campaign manager Public relations consultant | Lieutenant Governor of Minnesota | Stanford University (BA)Dartmouth College (MBA) | January 3, 2018 | 2026 Class 2 | Minneapolis |
| Mississippi | | Roger Wicker | | Republican | (1951-07-05) July 5, 1951 | U . Air Force officer/Judge Advocate Lawyer U . House staffer | U . House Mississippi Senate | University of Mississippi (BA, JD) | December 31, 2007 | 2030 Class 1 | Tupelo |
| | Cindy Hyde-Smith | | Republican | (1959-05-10) May 10, 1959 | Lobbyist Farmer | Mississippi Commissioner of Agriculture and Commerce Mississippi Senate | Copiah-Lincoln Community College (AA)University of Southern Mississippi (BA) | April 9, 2018 | 2026 Class 2 | Brookhaven |
| Missouri | | Josh Hawley | | Republican | (1979-12-31) December 31, 1979 | Lawyer U . Supreme Court law clerk Professor | Missouri Attorney General | Stanford University (BA)Yale University (JD) | January 3, 2019 | 2030 Class 1 | Ozark |