| Name | Date | From | To | Constituency | Reason |
| Anne Marie Morris | 10 July 2017 | | Conservative | | Independent | Newton Abbot | Suspended from the Conservatives, pending investigation over using the remark "nigger in the woodpile". |
| 12 December 2017 | | Independent | | Conservative | Reinstated. |
| Jared O'Mara | 25 October 2017 | | Labour | | Independent | Sheffield Hallam | Suspended from Labour, pending investigation over alleged sexist and homophobic remarks. |
| 3 July 2018 | | Independent | | Labour | Reinstated. |
| 12 July 2018 | | Labour | | Independent | Resigned from Labour. |
| Kelvin Hopkins | 2 November 2017 | | Labour | | Independent | Luton North | Suspended from Labour, pending investigation into sexual allegations. |
| Charlie Elphicke | 3 November 2017 | | Conservative | | Independent | Dover | Suspended from the Conservatives, pending police investigation of "serious allegations". |
| 12 December 2018 | | Independent | | Conservative | Reinstated. |
| 22 July 2019 | | Conservative | | Independent | Suspended once again after being charged with sexual assault. |
| Ivan Lewis | 23 November 2017 | | Labour | | Independent | Bury South | Suspended from Labour, pending investigation of sexual harassment. Resigned from Labour on 20 December 2018. |
| Barry McElduff | 8 January 2018 | | Sinn Féin | | Independent | West Tyrone | Suspended from Sinn Féin over a social media video referencing the Kingsmill massacre. Resigned from parliament. |
| John Woodcock | 30 April 2018 | | Labour Co-op | | Independent | Barrow and Furness | Suspended from Labour over allegations of inappropriate messages to former staff. Resigned from Labour on 18 July 2018. |
| 10 July 2019 | | Independent | | The Independents | Formed new political grouping. |
| Ian Paisley | 24 July 2018 | | DUP | | Independent | North Antrim | Suspended from DUP for not disclosing financial interests from the Sri Lankan government, and then advocating for them. |
| 4 September 2018 | | Independent | Suspended | Suspended from the House of Commons on 24 July for 30 days beginning 4 September. |
| 21 November 2018 | Suspended | | DUP | Reinstated to the House of Commons and the DUP. |
| Andrew Griffiths | 21 August 2018 | | Conservative | | Independent | Burton | Suspended from the Conservatives, pending investigation of inappropriate behaviour with members of staff. |
| 12 December 2018 | | Independent | | Conservative | Reinstated. |
| Frank Field | 30 August 2018 | | Labour | | Independent | Birkenhead | Resigned from Labour. |
| 2 August 2019 | | Independent | | Birkenhead Social Justice | Founded new political party to contest the next election. |
| Stephen Lloyd | 6 December 2018 | | Liberal Democrats | | Independent | Eastbourne | Resigned the Liberal Democrats whip over the Brexit withdrawal agreement. |
| Fiona Onasanya | 19 December 2018 | | Labour | | Independent | Peterborough | Suspended from Labour after being convicted of perverting the course of justice. Expelled from Labour in January 2019. Removed from office on 1 May 2019 by a recall petition. |
| Luciana Berger | 18 February 2019 | | Labour Co-op | | Change UK | Liverpool Wavertree | Resigned from Labour, citing party's approach to Brexit and antisemitism. |
| 4 June 2019 | | Change UK | | Independent | Left Change UK following in order to "work cross party" and "respond flexibly". |
| 10 July 2019 | | Independent | | The Independents | Formed new political grouping. |
| 5 September 2019 | | The Independents | | Liberal Democrats | Joined the Liberal Democrats, citing the "moment of national crisis", as the most effective party to stop Brexit. |
| Ann Coffey | 18 February 2019 | | Labour | | Change UK | Stockport | Resigned from Labour, citing party's approach to Brexit and antisemitism. |
| Mike Gapes | | Labour Co-op | | Change UK | Ilford South |
| Chris Leslie | | Labour Co-op | | Change UK | Nottingham East |
| Gavin Shuker | | Labour Co-op | | Change UK | Luton South |
| 4 June 2019 | | Change UK | | Independent | Left Change UK following in order to "work cross party" and "respond flexibly". |
| 10 July 2019 | | Independent | | The Independents | Formed new political grouping. |
| Angela Smith | 18 February 2019 | | Labour | | Change UK | Penistone and Stocksbridge | Resigned from Labour, citing party's approach to Brexit and antisemitism. |
| 4 June 2019 | | Change UK | | Independent | Left Change UK following in order to "work cross party" and "respond flexibly". |
| 10 July 2019 | | Independent | | The Independents | Formed new political grouping. |
| 7 September 2019 | | The Independents | | Liberal Democrats | Defected to the Liberal Democrats. |
| Chuka Umunna | 18 February 2019 | | Labour | | Change UK | Streatham | Resigned from Labour, citing party's approach to Brexit and antisemitism. |
| 4 June 2019 | | Change UK | | Independent | Left Change UK following in order to "work cross party" and "respond flexibly". |
| 13 June 2019 | | Independent | | Liberal Democrats | Decided against the need for a new political party. |
| Joan Ryan | 19 February 2019 | | Labour | | Change UK | Enfield North | Resigned from Labour, citing party's approach to Brexit and antisemitism. |
| Anna Soubry | 20 February 2019 | | Conservative | | Change UK | Broxtowe | Resigned from the Conservatives in response to its perceived move to the political right, such as "Hard Brexit" policies. |
| Heidi Allen | 20 February 2019 | | Conservative | | Change UK | South Cambridgeshire |
| 4 June 2019 | | Change UK | | Independent | Wanted to "work cross party" and "respond flexibly". |
| 10 July 2019 | | Independent | | The Independents | Formed new political grouping. |
| 7 October 2019 | | The Independents | | Liberal Democrats | Joined the Lib Dems, citing effectiveness as part of a team, rejecting the status quo, and stopping Brexit. |
| Sarah Wollaston | 20 February 2019 | | Conservative | | Change UK | Totnes | Resigned from the Conservatives in response to its perceived move to the political right, such as "Hard Brexit" policies. |
| 4 June 2019 | | Change UK | | Independent | Wanted to "work cross party" and "respond flexibly". |
| 14 August 2019 | | Independent | | Liberal Democrats | Joined the Lib Dems to make the case for the UK to "remain at the heart of Europe". |
| Ian Austin | 22 February 2019 | | Labour | | Independent | Dudley North | Resigned from Labour, blaming leader Jeremy Corbyn for "creating a culture of extremism and intolerance". |