| Image | Senator | State | Tenure | Party | Congress | Notes |
| Start | End | Duration |
| | Hiram Rhodes Revels(1827–1901) | Mississippi | February 25, 1870 | March 3, 1871 | 1 year, 7 days | | Republican | 41st(1869–1871) | Elected to complete an unfinished term after Mississippi was readmitted to the Union on February 23, 1870. First African American to serve in the United States Senate and Congress. Retired. |
| | Blanche Bruce(1841–1898) | Mississippi | March 4, 1875 | March 4, 1881 | 6 years, 0 days | | Republican | 44th(1875–1877) | First African American to serve a full six-year term as a United States senator. The only senator to be a former slave. Retired. |
| 45th(1877–1879) |
| 46th(1879–1881) |
| | Edward Brooke(1919–2015) | Massachusetts | January 3, 1967 | January 3, 1979 | 12 years, 0 days | | Republican | 90th(1967–1969) | First African American elected to the Senate by direct election. First African American to serve in Congress from Massachusetts. Lost reelection. |
| 91st(1969–1971) |
| 92nd(1971–1973) |
| 93rd(1973–1975) |
| 94th(1975–1977) |
| 95th(1977–1979) |
| | Carol Moseley Braun(born 1947) | Illinois | January 3, 1993 | January 3, 1999 | 6 years, 0 days | | Democratic | 103rd(1993–1995) | First African-American female and African-American Democrat to serve in the United States Senate. First African American to serve in the Senate from Illinois. Lost reelection. |
| 104th(1995–1997) |
| 105th(1997–1999) |
| | Barack Obama(born 1961) | Illinois | January 3, 2005 | November 16, 2008 | 3 years, 318 days | | Democratic | 109th(2005–2007) | First African-American senator to be elected President of the United States. Resigned following election as president. |
| 110th(2007–2009) |
| | Roland Burris(born 1937) | Illinois | January 15, 2009 | November 29, 2010 | 1 year, 318 days | | Democratic | 111th(2009–2011) | Appointed by Illinois Governor Rod Blagojevich to fill vacancy caused by the resignation of President-elect Barack Obama. First African American to succeed another African American in the Senate. Not a candidate during special election following his appointment. |
| | Tim Scott(born 1965) | South Carolina | January 2, 2013 | Incumbent | 12 years, 303 days | | Republican | 112th(2011–2013) | Appointed by South Carolina Governor Nikki Haley to fill vacancy caused by the resignation of Jim DeMint. First African American to serve in the Senate from South Carolina. First African American to serve in both chambers of the United States Congress. |
| 113th(2013–2015) |
| 114th(2015–2017) |
| 115th(2017–2019) |
| 116th(2019–2021) |
| 117th(2021–2023) |
| 118th(2023–2025) |
| 119th(2025–present) |
| | Mo Cowan(born 1969) | Massachusetts | February 1, 2013 | July 16, 2013 | 165 days | | Democratic | 113th(2013–2015) | Appointed by Massachusetts Governor Deval Patrick to fill vacancy caused by the resignation of John Kerry. Not a candidate during special election following his appointment. First African-American senator appointed by an African-American governor. The first African American to serve alongside another African-American senator: Tim Scott. Retired. |
| | Cory Booker(born 1969) | New Jersey | October 31, 2013 | Incumbent | 12 years, 1 day | | Democratic | 113th(2013–2015) | First African American to serve in the Senate from New Jersey. First African American to be elected to the Senate by special election. |
| 114th(2015–2017) |
| 115th(2017–2019) |
| 116th(2019–2021) |
| 117th(2021–2023) |
| 118th(2023–2025) |
| 119th(2025–present) |
| | Kamala Harris (born 1964) | California | January 3, 2017 | January 18, 2021 | 4 years, 15 days | | Democratic | 115th(2017–2019) | First African American to serve in the Senate from California. First African-American senator to be elected as Vice President. Resigned following election as Vice President of the United States. |
| 116th(2019–2021) |
| 117th(2021–2023) |
| | Raphael Warnock(born 1969) | Georgia | January 20, 2021 | Incumbent | 4 years, 285 days | | Democratic | 117th(2021–2023) | First African American to serve in the Senate from Georgia. |
| 118th(2023–2025) |
| 119th(2025–present) |
| | Laphonza Butler(born 1979) | California | October 3, 2023 | December 8, 2024 | 1 year, 66 days | | Democratic | 118th(2023–2025) | Appointed by Governor Gavin Newsom to fill the vacancy created by the death of Senator Dianne Feinstein. First openly LGBT African-American senator. Not a candidate for election. Resigned. |
| | Angela Alsobrooks(born 1971) | Maryland | January 3, 2025 | Incumbent | 302 days | | Democratic | 119th(2025–present) | First African American to serve in the Senate from Maryland. First African-American woman to serve alongside another African-American woman in the Senate: Lisa Blunt Rochester. |
| | Lisa Blunt Rochester(born 1962) | Delaware | January 3, 2025 | Incumbent | 302 days | | Democratic | 119th(2025–present) | First African American to serve in the Senate from Delaware. First African-American woman to serve alongside another African-American woman in the Senate: Angela Alsobrooks. |
