| Year | Record | Pct | Notes |
| | | | LSU did not make the tournament from 1947 to 1974NOTE: LSU was invited to play in the 1961 NCAA tournament as SEC champion, but declined. |
| 1975 | 1–2 | 333 | Eliminated by Miami in the South Regional semifinals |
| | | | LSU did not make the tournament from 1976 to 1984 |
| 1985 | 0–2 | 000 | Eliminated by Lamar in NCAA Central Regional |
| 1986 | 5–2 | 714 | Won NCAA South I RegionalCollege World Series (5th place) |
| 1987 | 6–2 | 750 | Won NCAA South II RegionalCollege World Series (4th place) |
| | | | LSU did not make the tournament in 1988 |
| 1989 | 7–3 | 700 | Won the NCAA Central RegionalCollege World Series (3rd place) |
| 1990 | 7–3 | 700 | Won the NCAA South I RegionalCollege World Series (3rd place) |
| 1991 | 8–0 | 1.000 | Won the NCAA South RegionalCollege World Series champions |
| 1992 | 2–2 | 500 | Eliminated by Cal St. Fullerton in the NCAA South II Regional semifinals |
| 1993 | 8–2 | 800 | Won the NCAA South RegionalCollege World Series champions |
| 1994 | 4–2 | 667 | Won the NCAA South RegionalCollege World Series (7th place) |
| 1995 | 2–2 | 500 | Eliminated by Rice in NCAA South Regional semifinals |
| 1996 | 8–0 | 1.000 | Won the NCAA South II RegionalCollege World Series champions |
| 1997 | 9–1 | 900 | Won the NCAA South I RegionalCollege World Series champions |
| 1998 | 6–2 | 750 | Won the NCAA South II RegionalCollege World Series (3rd place) |
| 1999 | 4–3 | 571 | Won the Baton Rouge RegionalEliminated by Alabama in the Tuscaloosa Super Regional |
| 2000 | 9–0 | 1.000 | Won the Baton Rouge RegionalWon the Baton Rouge Super Regional vs. UCLACollege World Series champions |
| 2001 | 4–3 | 571 | Won the Baton Rouge RegionalEliminated by Tulane in the Metairie Super Regional |
| 2002 | 4–3 | 571 | Won the Baton Rouge RegionalEliminated by Rice in the Houston Super Regional |
| 2003 | 5–3 | 625 | Won the Baton Rouge RegionalWon the Baton Rouge Super Regional vs. BaylorCollege World Series (7th place) |
| 2004 | 5–2 | 714 | Won the Baton Rouge RegionalWon the Baton Rouge Super Regional vs. Texas A&MCollege World Series (7th place) |
| 2005 | 2–2 | 500 | Eliminated by Rice in Baton Rouge Regional Finals |
| | | | LSU did not make the tournament in 2006 and 2007 |
| 2008 | 6–3 | 667 | Won the Baton Rouge RegionalWon the Baton Rouge Super Regional vs. UC IrvineCollege World Series (5th place) |
| 2009 | 10–1 | 909 | Won the Baton Rouge RegionalWon the Baton Rouge Super Regional vs. RiceCollege World SeriesWon College World Series Final 2–1 vs. Texas |
| 2010 | 1–2 | 333 | Eliminated by UCI in the Los Angeles Regional |
| | | | LSU did not make the tournament in 2011 |
| 2012 | 4–2 | 667 | Won the Baton Rouge RegionalEliminated by Stony Brook in the Baton Rouge Super Regional |
| 2013 | 5–2 | 714 | Won the Baton Rouge RegionalWon the Baton Rouge Super Regional vs. OklahomaCollege World Series (7th place) |
| 2014 | 2–2 | 500 | Eliminated by Houston in the Baton Rouge Regional Final |
| 2015 | 6–2 | 750 | Won the Baton Rouge RegionalWon the Baton Rouge Super Regional vs. Louisiana-LafayetteCollege World Series (5th place) |
| 2016 | 3–3 | 500 | Won the Baton Rouge Regional Eliminated by Coastal Carolina in the Baton Rouge Super Regional |
| 2017 | 9–3 | 750 | Won the Baton Rouge Regional Won the Baton Rouge Super Regional vs. Mississippi StateCollege World SeriesLost College World Series Final 2–0 vs. Florida |
| 2018 | 2–2 | 500 | Eliminated by Oregon State in the Corvallis Regional Final |
| 2019 | 3–2 | 600 | Won the Baton Rouge RegionalEliminated by Florida State in the Baton Rouge Super Regional |
| | | | Tournament not held in 2020 due to the COVID-19 pandemic |
| 2021 | 4–3 | 571 | Won the Eugene RegionalEliminated by Tennessee in the Knoxville Super Regional |
| 2022 | 2–2 | 500 | Eliminated by Southern Miss in the Hattiesburg Regional Final |
| 2023 | 11–2 | 846 | Won the Baton Rouge Regional Won the Baton Rouge Super Regional vs. KentuckyCollege World SeriesWon College World Series Final 2–1 vs. Florida |
| 2024 | 3–2 | 600 | Eliminated by North Carolina in the Chapel Hill Regional Final |
| 2025 | 10-1 | 909 | Won the Baton Rouge Regional Won the Baton Rouge Super Regional vs. West VirginiaCollege World SeriesWon College World Series Final 2–0 vs. Coastal Carolina |
| Total | 187–75 | 714 | Total NCAA tournament Appearances: 37 |