| Organizations | Year | Category | Work | Result | Ref. |
| AACTA Awards | 2026 | Best Lead Actress in a Television Drama | Apple Cider Vinegar | Pending | |
| Astra Film Awards | 2020 | Best Performance by an Actress 23 and Under | Booksmart | Won | |
| Next Generation of Hollywood | Herself | Won |
| Astra TV Awards | 2022 | Best Supporting Actress in a Limited Series and Movie | Dopesick | Won | |
| 2024 | Best Actress in a Limited Series or TV Movie | No One Will Save You | Nominated | |
| 2025 | Best Actress in a Limited Series or TV Movie | Apple Cider Vinegar | Nominated | |
| Best Guest Actress in a Drama Series | The Last of Us | Nominated |
| BAFTA Awards | 2019 | Rising Star Award | Herself | Nominated | |
| Behind the Voice Actors | 2017 | Best Vocal Ensemble in a Video Game | Uncharted 4: A Thief's End | Nominated | |
| CinemaCon | 2019 | Female Stars of Tomorrow (shared with Beanie Feldstein) | Booksmart | Won | |
| Critics' Choice Television Awards | 2019 | Best Actress in a Miniseries or TV Movie | Unbelievable | Nominated | |
| 2021 | Best Supporting Actress in a Miniseries or TV Movie | Dopesick | Nominated | |
| 2023 | Best Actress in a Miniseries or TV Movie | No One Will Save You | Nominated | |
| Critics' Choice Super Awards | 2024 | Best Actress in a Science Fiction/Fantasy Movie | No One Will Save You | Nominated | |
| Detroit Film Critics Society | 2019 | Best Breakthrough Performance | Booksmart / Them That Follow | Nominated | |
| Dorian Awards | 2020 | Rising Star of the Year Award | Herself | Nominated | |
| Fangoria Chainsaw Awards | 2024 | Best Lead Performance | No One Will Save You | Nominated | |
| Golden Globe Awards | 2019 | Best Actress – Miniseries or Television Film | Unbelievable | Nominated | |
| 2021 | Best Supporting Actress – Series, Miniseries or Television Film | Dopesick | Nominated | |
| Gracie Awards | 2022 | Actress in a Leading Role – Limited Series or TV Movie | Dopesick | Won | |
| Indiana Film Journalists Association | 2019 | Best Actress | Booksmart | Nominated | |
| Logie Awards | 2025 | Best Lead Actress in a Drama | Apple Cider Vinegar | Nominated | |
| Newport Beach Film Festival | 2019 | Ensemble Cast | Them That Follow | Won | |
| Online Film & Television Association | 2020 | Best Actress in a Motion Picture or Limited Series | Unbelievable | Nominated | |
| 2022 | Best Supporting Actress in a Motion Picture or Limited Series | Dopesick | Runner-up | |
| 2025 | Best Actress in a Motion Picture, Limited or Anthology Series | Apple Cider Vinegar | Nominated | |
| Best Guest Actress in a Drama Series | The Last of Us | Won |
| Phoenix Film Critics Society | 2013 | Best Youth Performance – Female | Short Term 12 | Nominated | |
| Primetime Emmy Awards | 2022 | Outstanding Supporting Actress in a Limited Series or Movie | Dopesick | Nominated | |
| 2025 | Outstanding Guest Actress in a Drama Series | The Last of Us | Nominated | |
| TCA Awards | 2020 | Individual Achievement in Drama | Unbelievable | Nominated | |
| Young Artist Awards | 2011 | Best Guest Starring Young Actress – Television Series | Private Practice | Nominated | |
| 2012 | Best Supporting Young Actress – Feature Film | Bad Teacher | Nominated | |
| Best Supporting Young Actress – Television Series | Last Man Standing | Nominated |
| Best Recurring Young Actress – Television Series | Justified | Nominated |