| Award ceremony | Year | Category | Nominee / Work | Result | Ref. |
| APAN Star Awards | 2013 | Popular Star Award | Five Fingers | Won | |
| 2020 | Top Excellence Award, Actor in a Miniseries | Hyena | Nominated | |
| 2025 | The Trauma Code: Heroes on Call, Love Your Enemy | Pending | |
| Asia Artist Awards | 2018 | Artist of the Year | Ju Ji-hoon | Won | |
| Best Actor | Won |
| Asia Model Awards | 2008 | Star Prize | Ju Ji-hoon | Won | |
| 2020 | Asia Star Award | Ju Ji-hoon | Won | |
| Baeksang Arts Awards | 2006 | Best New Actor – Television | Princess Hours | Nominated | |
| 2009 | Most Popular Actor – Film | Antique | Won | |
| Best New Actor – Film | Nominated | |
| 2019 | Best Actor – Film | Dark Figure of Crime | Nominated | |
| 2020 | Best Actor – Television | Hyena | Nominated | |
| 2025 | The Trauma Code: Heroes on Call | Won | |
| Blue Dragon Film Awards | 2018 | Popular Star Award | The Spy Gone North | Won | |
| Best Actor | Dark Figure of Crime | Nominated | |
| Best Supporting Actor | The Spy Gone North | Nominated | |
| Blue Dragon Series Awards | 2025 | Best Actor | The Trauma Code: Heroes on Call | Won | |
| Buil Film Awards | 2017 | Best Supporting Actor | Asura: The City of Madness | Nominated | |
| 2018 | The Spy Gone North | Won | |
| 2019 | Best Actor | Dark Figure of Crime | Nominated | |
| Chunsa Film Art Awards | 2017 | Best Supporting Actor | Asura: The City of Madness | Nominated | |
| 2019 | Best Actor | Dark Figure of Crime | Won | |
| Best Supporting Actor | The Spy Gone North | Nominated | |
| FUNdex Awards | 2025 | Best Actor of OTT Original Drama | The Trauma Code: Heroes on Call | Pending | |
| Popular Star Prize – K-Drama Actor | Pending |
| Global OTT Awards | 2020 | Best Lead Actor | Kingdom | Won | |
| 2025 | The Trauma Code: Heroes on Call | Nominated | |
| Golden Cinema Film Festival | 2019 | Best Actor | Dark Figure of Crime | Won | |
| KBS Drama Awards | 2007 | Excellence Award, Actor in a Miniseries | Lucifer | Nominated | |
| KCA Consumer Day Awards | 2018 | Best Actor | Along with the Gods: The Two Worlds / Dark Figure of Crime | Won | |
| KOFRA Film Awards | 2019 | Best Supporting Actor | The Spy Gone North | Won | |
| Korea Best Dresser Swan Awards | 2004 | Best Male Model | Ju Ji-hoon | Won | |
| 2005 | Won | |
| Korean Association of Film Critics Awards | 2018 | Best Supporting Actor | The Spy Gone North | Won | |
| Korean Film Producers Association Awards | 2018 | Best Actor | Dark Figure of Crime | Won | |
| Marie Claire Asia Star Awards | 2018 | Asian Star Award | Along with the Gods: The Two Worlds / Dark Figure of Crime | Won | |
| MBC Drama Awards | 2006 | Best New Actor | Princess Hours | Won | |
| 2013 | Excellence Award, Actor in a Miniseries | Medical Top Team | Nominated | |
| 2019 | Top Excellence Award, Actor in a Monday-Tuesday Miniseries | Item | Nominated | |
| SBS Drama Awards | 2012 | Excellence Award, Actor in a Weekend/Daily Drama | Five Fingers | Nominated | |
| 2015 | Excellence Award, Actor in a Drama Special | Mask | Won | |
| Top 10 Star Award | Won | |
| 2020 | Top Excellence Award, Actor in a Miniseries Action Drama | Hyena | Won | |
| Best Couple Award | Ju Ji-hoon (with Kim Hye-soo)Hyena | Nominated | |
| Grand Prize (Daesang) | Hyena | Nominated | |
| Seoul International Drama Awards | 2025 | Outstanding Korean Actor | The Trauma Code: Heroes on Call | Won | |
| Style Magazine | 2005 | Most Stylish Male Model | Ju Ji-hoon | Won | |
| The Korea Film Actor's Association | 2016 | Popular Film Star Award | Asura: The City of Madness | Won | |
| The Photographers' Association | 2005 | Best Male Model | Ju Ji-hoon | Won | |