| Res. | Record | Opponent | Method | Event | Date | Round | Time | Location | Notes |
| Win | 22–9 (1) | Zhang Mingyang | TKO (leg kicks and punches) | UFC Fight Night: Walker vs. Zhang | August 23, 2025 | 2 | 2:37 | Shanghai, China | Performance of the Night. |
| Loss | 21–9 (1) | Volkan Oezdemir | KO (punch) | UFC on ABC: Whittaker vs. Aliskerov | June 22, 2024 | 1 | 2:28 | Riyadh, Saudi Arabia | |
| Loss | 21–8 (1) | Magomed Ankalaev | KO (punches) | UFC Fight Night: Ankalaev vs. Walker 2 | January 13, 2024 | 2 | 2:42 | Las Vegas, Nevada, United States | |
| NC | 21–7 (1) | Magomed Ankalaev | NC (illegal knee) | UFC 294 | October 21, 2023 | 1 | 3:13 | Abu Dhabi, United Arab Emirates | Accidental illegal knee rendered Walker unable to continue. |
| Win | 21–7 | Anthony Smith | Decision (unanimous) | UFC on ABC: Rozenstruik vs. Almeida | May 13, 2023 | 3 | 5:00 | Charlotte, North Carolina, United States | |
| Win | 20–7 | Paul Craig | TKO (punches) | UFC 283 | January 21, 2023 | 1 | 2:16 | Rio de Janeiro, Brazil | |
| Win | 19–7 | Ion Cuțelaba | Submission (rear-naked choke) | UFC 279 | September 10, 2022 | 1 | 4:37 | Las Vegas, Nevada, United States | Performance of the Night. |
| Loss | 18–7 | Jamahal Hill | KO (punch) | UFC Fight Night: Walker vs. Hill | February 19, 2022 | 1 | 2:55 | Las Vegas, Nevada, United States | |
| Loss | 18–6 | Thiago Santos | Decision (unanimous) | UFC Fight Night: Santos vs. Walker | October 2, 2021 | 5 | 5:00 | Las Vegas, Nevada, United States | |
| Win | 18–5 | Ryan Spann | KO (elbows and punches) | UFC Fight Night: Covington vs. Woodley | September 19, 2020 | 1 | 2:43 | Las Vegas, Nevada, United States | |
| Loss | 17–5 | Nikita Krylov | Decision (unanimous) | UFC Fight Night: Lee vs. Oliveira | March 14, 2020 | 3 | 5:00 | Brasília, Brazil | |
| Loss | 17–4 | Corey Anderson | TKO (punches) | UFC 244 | November 2, 2019 | 1 | 2:07 | New York City, New York, United States | |
| Win | 17–3 | Misha Cirkunov | TKO (flying knee and punches) | UFC 235 | March 2, 2019 | 1 | 0:38 | Las Vegas, Nevada, United States | Performance of the Night. |
| Win | 16–3 | Justin Ledet | TKO (spinning backfist and punches) | UFC Fight Night: Assunção vs. Moraes 2 | February 2, 2019 | 1 | 0:15 | Fortaleza, Brazil | Performance of the Night. |
| Win | 15–3 | Khalil Rountree Jr. | KO (elbow) | UFC Fight Night: Magny vs. Ponzinibbio | November 17, 2018 | 1 | 1:57 | Buenos Aires, Argentina | Performance of the Night. |
| Win | 14–3 | Henrique da Silva | Decision (unanimous) | Dana White's Contender Series Brazil 2 | August 11, 2018 | 3 | 5:00 | Las Vegas, Nevada, United States | |
| Win | 13–3 | Cheick Kone | TKO (punches) | European Beatdown 3 | March 17, 2018 | 1 | 3:04 | Mons, Belgium | Won the EBD Light Heavyweight Championship. |
| Win | 12–3 | Jędrzej Maćkowiak | KO (knee and punches) | Krwawy Sport 1 | March 11, 2018 | 2 | 2:42 | Southampton, England | Heavyweight bout. |
| Win | 11–3 | Stuart Austin | KO (knee) | Ultimate Challenge MMA 54 | February 10, 2018 | 1 | 2:44 | London, England | Won the UCMMA Light Heavyweight Championship. |
| Win | 10–3 | Rodrigo Jesus | TKO (punches) | Brave CF 8 | August 12, 2017 | 1 | 2:18 | Curitiba, Brazil | |
| Win | 9–3 | Luis Guilherme de Andrade | Submission (guillotine choke) | Katana Fight: Gold Edition | March 25, 2017 | 1 | 0:29 | Colombo, Brazil | Return to Light Heavyweight. |
| Loss | 8–3 | Henrique Silva Lopes | KO (punches) | Jungle Fight 88 | June 25, 2016 | 1 | 0:18 | Poços de Caldas, Brazil | |
| Win | 8–2 | Fábio Vasconcelos | TKO (punches) | Imortal FC 4 | May 21, 2016 | 1 | 4:10 | São José dos Pinhais, Brazil | |
| Loss | 7–2 | Klidson Abreu | Submission (rear-naked choke) | Samurai FC 12 | October 10, 2015 | 2 | 3:10 | Curitiba, Brazil | Heavyweight debut. For the vacant Samurai FC Heavyweight Championship. |
| Win | 7–1 | Murilo Grittz | TKO (punches) | PRVT: Garuva Top Fight | August 16, 2015 | 1 | 0:56 | Garuva, Brazil | |
| Win | 6–1 | Marck Polimeno | Submission (rear-naked choke) | PRVT: Afonso Pena Top Fight 3 | June 28, 2015 | 1 | 0:38 | São José dos Pinhais, Brazil | |
| Win | 5–1 | Ricardo Pandora | TKO (punches) | Imortal FC 1 | June 13, 2015 | 1 | 3:20 | São José dos Pinhais, Brazil | |
| Win | 4–1 | Andrew Flores Smith | TKO (punches) | Peru FC 21 | May 28, 2015 | 3 | 0:28 | Lima, Peru | |
| Loss | 3–1 | Wagner Prado | TKO (punches) | Circuito Team Nogueira MMA Beach 1 | November 29, 2014 | 2 | 3:40 | Rio de Janeiro, Brazil | |
| Win | 3–0 | João Vitor Lopes da Silva | TKO (punches) | Gigante Fight MMA 2 | October 11, 2014 | 1 | N/A | Rio de Janeiro, Brazil | |
| Win | 2–0 | Vitor Casanova | TKO (punches) | Ubá Fight 5 | September 13, 2014 | 1 | 4:38 | Ubá, Brazil | |
| Win | 1–0 | Francisco Francisco | TKO (knees and punches) | Circuito Invictus de MMA 2 | December 14, 2013 | 1 | 0:49 | Rio de Janeiro, Brazil | |
