| Year | Titles (A-side, B-side)Both sides from same album except where indicated | Chart positions | Album |
| US Billboard | US Cash Box | US A/C | CAN | AUS | SA | UK | NLD | JPN |
| 1967 | "Society's Child (Baby I've Been Thinking)"b/w "Letter to Jon" (Non-album track) | 14 | 13 | — | 13 | — | — | — | — | — | Janis Ian (Verve Forecast) |
| "Younger Generation Blues"b/w "I'll Give You a Stone If You'll Throw It" | — | — | — | — | — | — | — | — | — |
| "Insanity Comes Quietly to the Structured Mind"b/w "Sunflakes Fall, Snowrays Call" | 109 | 82 | — | 76 | — | — | — | — | — | For All The Seasons Of Your Mind |
| 1968 | "A Song for All the Seasons of Your Mind"b/w "Lonely One" | — | — | — | — | — | — | — | — | — |
| "Friends Again"b/w "Lady of the Night" (Non-album track) | — | — | — | — | — | — | — | — | — | The Secret Life of J. Eddy Fink |
| "Janey's Blues"b/w "Everybody Knows" (from The Secret Life of J. Eddy Fink) | — | — | — | — | — | — | — | — | — | Janis Ian (Verve Forecast) |
| 1969 | "Calling Your Name"b/w "Month of May" | — | — | — | — | — | — | — | — | — | Who Really Cares |
| 1971 | "He's a Rainbow"b/w "Here in Spain" (US) or "See My Grammy Ride" (UK) | — | — | — | — | — | — | — | — | — | Present Company |
| 1974 | "The Man You Are in Me"b/w "Jesse" | 104 | 105 | 33 | — | — | — | — | — | — | Stars |
| 1975 | "When the Party's Over"b/w "Bright Lights and Promises" | — | 112 | 20 | — | — | — | — | — | — | Between the Lines |
| "At Seventeen"b/w "Stars" (from Stars) | 3 | 1 | 1 | 6 | 23 | — | 54 | — | — |
| "In the Winter"b/w "Thankyous" (from Stars) | — | 97 | 21 | — | — | — | — | — | — |
| 1976 | "Boy I Really Tied One On"b/w "Aftertones" | — | — | 43 | — | 50 | — | — | — | — | Aftertones |
| "I Would Like to Dance"b/w "Goodbye To Morning" | — | — | 28 | 86 | — | — | — | — | — |
| "Roses"b/w "Love Is Blind" | — | — | 37 | — | — | — | — | — | — |
| "Love Is Blind"b/w "Miracle Row" (from Miracle Row) | — | — | — | — | — | — | — | — | 1 |
| "Between the Lines"b/w "Sweet Sympathy" (from Stars) | — | — | — | — | — | — | — | — | 90 | Between The Lines |
| 1977 | "Miracle Row"b/w "Take to the Sky" | — | — | — | — | — | — | — | — | — | Miracle Row |
| "I Want to Make You Love Me"b/w "Candlelight" | — | — | — | — | — | — | — | — | — |
| "Will You Dance?"b/w "I Want to Make You Love Me" | — | — | — | — | — | — | — | — | 40 |
| 1978 | "That Grand Illusion"b/w "Hopper Painting" | — | — | 43 | — | — | — | — | — | — | Janis Ian (Columbia) |
| "The Bridge"b/w "Do You Wanna Dance" | — | — | — | — | — | — | — | — | — |
| 1979 | "Here Comes the Night"b/w "Tonight Will Last Forever" (from Janis Ian (Columbia)) | — | — | — | — | — | — | — | — | — | Night Rains |
| "Fly Too High"b/w "Night Rains" | — | — | — | — | 7 | 1 | 44 | 5 | — |
| 1980 | "You Are Love"b/w "All to You" | — | — | — | — | — | — | — | — | 10 | "Virus" soundtrack (Japan release only) |
| "The Other Side of the Sun"b/w "Memories" | — | — | 47 | — | 44 | — | 44 | 30 | — | Night Rains |
| 1981 | "Under the Covers"b/w "Sugar Mountain" | 71 | 79 | — | — | — | — | — | — | — | Restless Eyes |
| "Restless Eyes"b/w "I Remember Yesterday" | — | — | — | — | — | — | — | — | — |
| 1985 | "Body Slave (Re-Mix)" b/w "Mechanical Telephone" (Australia) | — | — | — | — | — | — | — | — | — | Uncle Wonderful |
| "Heart Skip Too Many Beats" b/w "Sniper of the Heart" (Australia/New Zealand) | — | — | — | — | — | — | — | — | — |
| 1989 | "Heaven Knows" b/w "Heaven Knows (Non Vocal Version)" (Japan) | — | — | — | — | — | — | — | — | — | Non-album track |
| 1992 | "Days Like These" (promo) | — | — | — | — | — | — | — | — | — | Falling from Grace (Soundtrack) |
| "Walking On Sacred Ground" b/w "Cosmopolitan Girl (Live)" & "When He Was Here (Live)" (Europe) | — | — | — | — | — | — | — | — | — | Breaking Silence |
| 1993 | "Tattoo" b/w "Cosmopolitan Girl (Live)" & "When He Was Here (Live)" (Europe) | — | — | — | — | — | — | — | — | — |
| "Guess You Had To Be There" b/w "Breaking Silence" (Europe) | — | — | — | — | — | — | — | — | — |
| 1995 | "Tenderness" b/w "Take No Prisoners" & "When Angels Cry" (Europe) | — | — | — | — | — | — | — | — | — | Revenge |
| "Take Me Walking in the Rain" b/w "When the Silence Fall" | — | — | — | — | — | — | — | — | — |
| 1997 | "Honor Them All" (promo) | — | — | — | — | — | — | — | — | — | Hunger |
| 1998 | "Getting Over You" (promo) | — | — | — | — | — | — | — | — | — |
| 2000 | "Jolene" | — | — | — | — | — | — | — | — | — | God and the FBI |
| 2006 | "The Great Divide" | — | — | — | — | — | — | — | — | — | Folk Is the New Black |
| "Standing In the Shadows of Love" b/w "All Those Promises" & "Crocodile Song" | — | — | — | — | — | — | — | — | — |
| "Married In London" | — | — | — | — | — | — | — | — | — | Non-album track |
| 2010 | "Welcome Home (The Nebulas Song)" | — | — | — | — | — | — | — | — | — |
| "Every Woman's Song" (with Angela Aki) | — | — | — | — | — | — | — | — | 53 |
| 2012 | "The Tiny Mouse" | — | — | — | — | — | — | — | — | — | The Tiny Mouse Book/CD |
| 2013 | "Architect of All Creation" | — | — | — | — | — | — | — | — | — | The Singer & the Song audiobook |
| 2014 | "I'm Still Standing" | — | — | — | — | — | — | — | — | — | Strictly Solo |
