| Work | Description | Year of completion | Image |
| Basilica of Sant'Ambrogio | Basilica of Sant'Ambrogio The basilica of Sant'Ambrogio (basilega de Sant Ambroeus in Milanese dialect), whose full name is basilica romana minore collegiata abbaziale prepositurale di Sant'Ambrogio (its original early Christian name was basilica martyrum), is one of the oldest churches in Milan and is located in Piazza Sant'Ambrogio. It represents to this day not only a monument of the early Christian and medieval period, but also a fundamental point in the history of Milan and the Ambrosian Church. It is traditionally considered the second most important church in the city of Milan. | 386 | |
| Milan Cathedral | The Metropolitan Cathedral Basilica of the Nativity of the Blessed Virgin Mary, better known as the Milan Cathedral (Dòmm de Milan in Milanese dialect), is the cathedral of the Archdiocese of Milan. A symbol of the Lombard capital, and located in the square of the same name in the center of the metropolis, it is dedicated to Saint Mary of the Nativity. It is the largest church in Italy, the fourth largest in the world by area, and the sixth largest by volume. It is the seat of the parish of Santa Tecla in Milan Cathedral. | 1418 | |
| Castello Sforzesco | The Castello Sforzesco (Castell Sforzesch in Milanese dialect) is a fortification that stands in Milan just outside the city's historic center. It was erected in the 15th century by Francesco Sforza, who had recently become Duke of Milan, on the remains of an earlier medieval fortification dating back to the 14th century known as Castello di Porta Giovia (or Zobia). In the same area where Porta Giovia Castle stood, in Roman times, there was the Castrum Portae Jovis of the same name, one of the four defensive castles of Roman Milan. Considerably transformed and modified over the centuries, Castello Sforzesco was, between the 16th and 17th centuries, one of Europe's leading military citadels; restored in historicist style by Luca Beltrami between 1890 and 1905, it is now home to cultural institutions and important museums. It is one of the largest castles in Europe as well as one of the main symbols of Milan and its history. | 1360 | |
| Church of Santa Maria presso San Satiro | The church of Santa Maria presso San Satiro is a parish church in Milan. The construction of the church was undertaken at the end of the 15th century at the behest of Duke Gian Galeazzo Sforza and later continued by Ludovico il Moro as part of an ambitious program of renewal of the arts in the duchy, which included calling artists from all over Italy to the Milanese court: in fact, the building was designed according to new Renaissance forms imported into the duchy by Donato Bramante. The church, built by incorporating the older sacellum of San Satiro from which it took its name, is famous for housing the so-called Bramante faux choir, a masterpiece of Italian Renaissance perspective painting. | 1483 | |
| Church of Santa Maria delle Grazie | The church of Santa Maria delle Grazie is a basilica and sanctuary located in Milan, belonging to the Dominican Order and forming part of the parish of San Vittore al Corpo. The architecture of the tribune, built between 1492 and 1493 at the behest of the Duke of Milan Ludovico il Moro as a mausoleum for his family, constitutes one of the highest achievements of the Renaissance in northern Italy. It was the second Italian site after the rock drawings in Valcamonica to be classified as a UNESCO World Heritage Site, along with Leonardo da Vinci's Last Supper fresco located in the refectory of the convent (owned by the City of Milan). | 1497 | |
| The Last Supper | The Last Supper is a wall painting created with a mixed technique using dry paint on plaster (460×880 cm) by Leonardo da Vinci, dated 1495-1498 and preserved in the former Renaissance refectory of the convent adjacent to the sanctuary of Santa Maria delle Grazie in Milan. It is the most famous depiction of the Last Supper, a masterpiece of Leonardo and the Italian Renaissance in general. Despite this, the work - due to the unique experimental technique used by Leonardo that was incompatible with the humidity of the environment - has been in a poor state of preservation for centuries, which was improved as much as possible during one of the longest restorations in history, lasting from 1978 to 1999 using the most advanced techniques in the field. In 2014 it was the 13th most visited Italian state site. | 1498 | |
| Church of San Fedele | The Church of San Fedele (Gesa de San Fedee in Milanese dialect) is a Catholic church in Milan, built in the 16th century by order of St. Charles Borromeo to house the Society of Jesus. Because of the structure's adherence to St. Charles Borromeo's Instructiones, as well as the wide range of quotations from famous architectural models of the past and the many later churches that drew from the church, San Fedele is considered the model for sacred architecture in Counter-Reformation art. | 1579 | |
| Teatro alla Scala | The Teatro alla Scala, often informally referred to as "la Scala," is Milan's main opera house. Regarded as one of the most prestigious theaters in the world, it has for 246 years been home to leading artists in the international field of opera, and, more generally, classical music, often commissioning works that are still on the billboards of major theaters around the world. The theater was inaugurated on August 3, 1778 with Europa riconosciuta, composed for the occasion by Antonio Salieri, and took its name from the church of Santa Maria alla Scala, which was demolished to make way for the Nuovo Regio Ducal Teatro alla Scala. Since the year of its founding, it has been home to the choir of the same name, the orchestra, the ballet company, and since 1982 also to the Philharmonic. The theater complex is located in the square of the same name, next to the Casino Ricordi, now home to the Museo teatrale alla Scala. | 1778 | |
| Galleria Vittorio Emanuele II | Galleria Vittorio Emanuele II is a commercial gallery in Milan that, in the form of a covered pedestrian street, connects Piazza Duomo to Piazza della Scala. Due to the presence of elegant stores and bars, since its inauguration it was a meeting place for the Milanese bourgeoisie, so much so that it was nicknamed the "living room of Milan." Built in the Neo-Renaissance style, it is among the most celebrated examples of European cast-iron architecture and represents the archetype of the nineteenth-century shopping gallery. Called simply "the Galleria" by the Milanese, it is often regarded as one of the earliest examples of a shopping center in the world. | 1867 | |