| Year | Title | Role | Notes |
| 2000–2008 | Total Request Live | Herself | Co-host |
| 2001 | Becoming Presents: Wannabe | Herself | Correspondent, select episodes |
| 2002 | Dawson's Creek | VJ Hilarie | Episode: "100 Light Years from Home" |
| 2003–2009 | One Tree Hill | Peyton Sawyer | Main role; 130 episodes (Seasons 1–6) |
| 2003 | MTV's Iced Out New Year's Eve | Herself | Host |
| 2003 | MTV Does Miami | Herself | Co-host |
| 2003 | MTV Diary | Herself | Alongside One Tree Hill cast |
| 2003 | The Real World: Las Vegas | Herself | Reunion Host: 7 The Hard Way |
| 2003 | Pepsi Smash | Herself | Host |
| 2005 | Unscripted | Herself | Episode |
| 2008 | Little Britain USA | Lesbian College Student | Episode |
| 2010–2013 | White Collar | Sara Ellis | 22 episodes; Main role (Season 3); Recurring role (Seasons 2 and 4) |
| 2012 | Castle | Kay Cappuccio | Episode: "An Embarrassment of Bitches" |
| 2012 | Naughty or Nice | Krissy Kringle | Television film |
| 2013 | Grey's Anatomy | Dr. Lauren Boswell | Recurring role; 3 episodes |
| 2013 | Hostages | Samantha | Recurring role; 4 episodes |
| 2013 | Christmas on the Bayou | Katherine "Kat" | Television film |
| 2014–2015 | Forever | Iona Payne / Molly Dawes | Guest role; 2 episodes |
| 2015 | Surprised by Love | Josie Mayfield | Television film |
| 2015 | Extant | Anna Schaefer | Recurring role; 6 episodes |
| 2015 | Last Chance for Christmas | Annie | Television film |
| 2016 | Togetherness | Kennedy | Episode: "Advanced Pretend" |
| 2016 | Summer Villa | Terry Russell | Television film |
| 2016–2017 | Lethal Weapon | Karen Palmer | Recurring role; 6 episodes |
| 2018 | The Christmas Contract | Jolie Guidry | Television film; also co-producer |
| 2019 | A Christmas Wish | Faith | Television film; also producer |
| 2020 | Friday Night in with the Morgans | Herself | Co-host, also executive producer; 7 episodes |
| 2020 | Council of Dads | Margot | Recurring role; 6 episodes |
| 2020 | Dear Christmas | Cameo | Television film |
| 2021 | The Walking Dead | Lucille | Episode: "Here's Negan" |
| 2021–2024 | True Crime Story: It Couldn't Happen Here | Herself | Host; crime documentary series, 17 episodes; also executive producer |
| 2022 | Good Sam | Gretchen Taylor | Episode: "Keep Talking" |
| 2025 | The Walking Dead: Dead City | Lucille | Episode: "Novi Dan, Novi Početak" |
