| Year | Association | Category | Nominated work | Result | Ref. |
| 2011 | Imagen Award | Best Supporting Actress – Feature Film | Go for It! | Nominated | |
| 2012 | Imagen Award | Best Actress – Feature Film | Filly Brown | Won | |
| 2013 | ALMA Award | Achievement in Film (with Edward James Olmos, Michael D. Olmos, and Lou Diamond Phillips) | Won | |
| Inaugural Lupe Special Achievement Award | Honoree | Gina Rodriguez | Won | |
| 2014 | Imagen Award | Best Actress/Supporting Actress - Feature Film | Sleeping with the Fishes | Nominated | |
| Young Hollywood Award | Rising Star of the Year | — | Won | |
| 2015 | Golden Globe Award | Best Actress – Television Series Musical or Comedy | Jane the Virgin | Won | |
| Critics' Choice Award | Best Actress in a Comedy Series | Nominated | |
| EWwy Award | Best Actress – Comedy | Won | |
| Television Critics Association | Individual Achievement in Comedy | Nominated | |
| Teen Choice Award | Choice TV Actress – Comedy | Nominated | |
| Choice TV Breakout Star | Nominated |
| Choice TV Liplock (with Justin Baldoni) | Nominated |
| Imagen Awards | Best Actress – Television | Won | |
| Online Film & Television Association Award | Best Actress in a Comedy Series | Nominated | |
| Women's Image Network Award | Outstanding Actress in a Comedy Series | Nominated | |
| Dorian Award | Rising Star Award | — | Won | |
| Girl Power Media Role Model | Honoree | Jane the Virgin | Won | |
| NHMC Impact Gala Award | Honoree | Won | |
| Feelies Award | Best Actress | Won | |
| 2016 | Golden Globe Award | Best Actress – Television Series Musical or Comedy | Nominated | |
| NAACP Image Award | Outstanding Actress in a Comedy Series | Nominated | |
| Critics' Choice Award | Best Actress in a Comedy Series | Nominated | |
| Satellite Award | Best Actress – Television Series Musical or Comedy | Nominated | |
| Teen Choice Award | Choice Comedy TV Actress | Nominated | |
| Imagen Award | Best Actress – Television | Won | |
| CinemaCon Award | Female Star of Tomorrow | — | Won | |
| Unite 4 Humanity Award | Honoree | Gina Rodriguez | Won | |
| Lip Sync Battle Award | Performer | Won | |
| Feelies Award | Best Actress | Won | |
| TVLine Performance of the Week | Honoree | Won | |
| 2017 | Golden Globe Award | Best Actress – Television Series Musical or Comedy | Jane the Virgin | Nominated | |
| People's Choice Award | Favorite Comedic TV Actress | Nominated | |
| MTV Award | Best Actor in a Show | Nominated | |
| Teen Choice Award | Choice TV Actress - Comedy | Nominated | |
| Icon Hispanic Heritage Month | Honoree | Won | |
| ACLU Social Bill of Rights Award | Honoree | Won | |
| Tell Tale Award | Best Actress | Won | |
| Tell Tale Award | Jane and Petra Friendship | Won | |
| 2018 | MTV Award | Best Kiss (with Justin Baldoni) | Nominated | |
| Teen Choice Award | Choice TV Actress – Comedy | Won | |
| Choice TV Liplock (with Justin Baldoni) | Nominated |
| Tell Tale Award | Favorite Lead Actress in a Comedy Series | Won | |
| Eva Longoria Foundation Award | Honoree for Activism | Gina Rodriguez | Won | |
| ALMA Award | Honoree Award | Jane the Virgin | Won | |
| 2019 |
| TVLine Performance of the Week | Honoree | Won | |
| MTV Award | Best Performance in a Show | Nominated | |
| Imagen Award | Best Actress – Television | Nominated | |