Topzle Updated: Wikipedia source
Deirdre O'Connell is an American character actress who has worked extensively on stage, screen, and television. She has won a Tony Award and has been nominated for a Primetime Emmy Award and a Drama Desk Award.
| Year | Title | Role | Notes |
| 1987 | Tin Men | Nellie | |
| 1988 | Stars and Bars | Shanda Gage | |
| 1989 | Misplaced | Ella | |
| 1990 | Brain Dead | Mrs. Halsey | |
| 1990 | State of Grace | Irene | |
| 1990 | Pastime | Inez Brice | |
| 1992 | Falling from Grace | Sally Cutler | |
| 1992 | Straight Talk | Lily | |
| 1992 | Leaving Normal | Ellen | |
| 1992 | CrissCross | Shelly | |
| 1992 | Cool World | Isabelle Malley | |
| 1993 | Fearless | Nan Gordon | |
| 1995 | Smoke | Sue | |
| 1996 | Lifeform | Dr. Gracia Scott | |
| 1998 | City of Angels | Mrs. Balford | |
| 1999 | Just Looking | Mrs. Braverman | |
| 2001 | Hearts in Atlantis | Mrs. Gerber | |
| 2001 | Ball in the House | Phyllis | |
| 2002 | Dragonfly | Gwyn | |
| 2003 | Secondhand Lions | Helen | |
| 2004 | Eternal Sunshine of the Spotless Mind | Hollis Mierzwiak | |
| 2004 | Imaginary Heroes | Marge Dwyer | |
| 2005 | Winter Passing | Deirdre | |
| 2005 | A Couple of Days and Nights | Cosmo | |
| 2006 | Stephanie Daley | Jane | |
| 2007 | Trainwreck: My Life as an Idiot | Cynthia | |
| 2008 | What Happens in Vegas | Mrs. Fuller | |
| 2008 | Synecdoche, New York | Ellen’s Mother | |
| 2008 | Wendy and Lucy | Deb (voice) | |
| 2009 | The Greatest | Joyce | |
| 2009 | A Dog Year | Donna Brady | |
| 2014 | Gabriel | Meredith | |
| 2014 | Apartment Troubles | Ina | |
| 2014 | St. Vincent | Linda | |
| 2014 | The Quitter | Kathleen Lembo | |
| 2016 | Detours | Beth | |
| 2017 | The Boy Downstairs | Amy | |
| 2018 | Diane | Donna | |
| 2018 | Lez Bomb | Rose | |
| 2020 | Before/During/After | Nancy | |
| 2022 | The Requin | Anne | |
| 2025 | Eddington | Dawn |
| Year | Title | Role | Notes |
| 1985–1986 | Loving | Sherri Rescott Watley | TV series |
| 1987 | Kate & Allie | Catherine | Episode: "Louis in Love" |
| 1990 | H.E.L.P. | Terrance | Episode: "Fire Down Below" |
| 1992 | Lifestories: Families in Crisis | Nancy Carlson | Episode: "Gunplay: The Last Day in the Life of Brian Darling" |
| 1993 | Sirens | Off. Heidi Schiller | Main role (season 1) |
| 1994 | Chicago Hope | Ellen Wheeler | Episodes: "You Gotta Have Heart", "Genevieve and Fat Boy" |
| 1994 | Law & Order | Jane Schuman | Episode: "Breeder" |
| 1995 | Fighting for My Daughter | Peggy | TV film |
| 1995 | Kansas | Holly | TV film |
| 1995 | Trial by Fire | Roberta | TV film |
| 1996 | Our Son, the Matchmaker | Winona | TV film |
| 1996 | Chasing the Dragon | Doris | TV film |
| 1996–1997 | Second Noah | Shirley Crockmeyer | Main role |
| 1997 | A Deadly Vision | Marilyn Middleton | TV film |
| 1997 | Breast Men | Lacey | TV film |
| 1998 | From the Earth to the Moon | Barbara Young | Episode: "The Original Wives Club" |
| 1998–1999 | Doctors | Suzanne Blum | Main role |
| 1999 | Murder in a Small Town | Kate Faxton | TV film |
| 2001 | Just Ask My Children | Ms. Landry | TV film |
| 2001 | The Practice | Jenny Baldwin | Episode: "Vanished: Parts 1 & 2" |
| 2001 | Law & Order | Joanna Wilder | Episode: "All My Children" |
| 2002 | Six Feet Under | LAC Arts Interviewer | Episode: "The Last Time" |
| 2005 | Law & Order: Criminal Intent | Nina Lipton | Episode: "The Good Child" |
| 2009–2010 | Law & Order | Dr. Valerie Knight | Guest role (season 20) |
| 2010 | You Don't Know Jack | Linda | TV film |
| 2011 | Unforgettable | Sue Kelly | Episode: "With Honor" |
| 2011 | Law & Order: Special Victims Unit | Judge Owens | Episode: "True Believers" |
| 2012 | Person of Interest | Joan | Episode: "Risk" |
| 2012 | The Closer | Liz Provenza | Episode: "Fool's Gold" |
| 2014 | Nurse Jackie | Helen | Episodes: "Rag and Bone", "Candyman", "Sisterhood" |
| 2014–2018 | The Affair | Athena Bailey | Recurring role |
| 2016–2018 | The Path | Gab Armstrong | Recurring role |
| 2017 | Madam Secretary | Audrey Stewart | Episode: "Article 5" |
| 2017 | The Holdouts | Annie | TV film |
| 2018 | $1 | Carol | "1.3" |
| 2018 | Daredevil | Anna Nelson | 3 episodes |
| 2021 | Tell Me Your Secrets | Gayle Scott | Episode: "Someone Worse Than Me" |
| 2022–2024 | Outer Range | Patricia Tillerson | 5 episodes |
| 2024 | The Penguin | Francis Cobb | Miniseries; main role |
| 2025 | The Beast in Me | Carol McGiddish | 4 episodes |