| Year | Event | Location | Notes |
| 2010–2013 | Trevor Live | Los Angeles | Benefit for The Trevor Project. In 2010, Criss sang "Not Alone" and "Teenage Dream" with Glee's Dalton Academy Warblers and Katy Perry, in 2011, he sang Tom Jones' hit, "It's Not Unusual", in 2012 he sang an acoustic version of Katy Perry's "Part of Me", and in 2013, he co-sang lead, with the cast of Glee, the Charlie Chaplin song Smile". |
| 2011 | MusiCares Person of the Year | Los Angeles | Criss and Glee's Dalton Academy Warblers performed for Barbra Streisand, in honor of her being named MusiCares Person of the Year by the MusiCares Foundation. |
| 2011 | Glee Live! In Concert! | US, Canada, England & Ireland | The 16th most successful concert tour of 2011, grossing more than $40 million, with total attendance topping 485,000. All 40 dates sold out, including shows at Staples Center, Nassau Coliseum, and The O2 Arenas in London and Dublin. |
| 2011 | ASCAP Pop Music Awards | Los Angeles | Criss paid tribute to Rod Stewart by singing a ballad version of Stewart's song "Da Ya Think I'm Sexy?", while accompanying himself on piano. |
| 2011 | Billboard / Hollywood Reporter Film & TV Music Conference | Los Angeles | Criss honored composer Alan Menken with a medley of his own Disney songs, singing alongside Broadway star Lea Salonga. |
| 2011 | The SPACE Tour | New York & Boston | StarKid Productions' first national concert tour. Majority of songs performed were written and composed by Criss. |
| 2011 | Sing Out, Raise Hope, Benefit Concert | New York | Criss performed at Lincoln Center with the a cappella singing groups of Harvard University's Krokodiloes, Princeton University's Nassoons, and Yale University's The Whiffenpoofs, at a benefit concert for the Elizabeth Glaser Pediatric AIDS Foundation and The Trevor Project. |
| 2012 | E! Entertainment pre-Oscar Show | Los Angeles | Criss sang "The Rainbow Connection" with Kermit the Frog for the pre-show of the 84th Academy Awards. |
| 2012 | Apocalyptour | New York & Los Angeles | StarKid Productions' second national concert tour. |
| 2012 | Fundraiser for Barack Obama | Los Angeles | Criss performed for the President of the United States at an LGBT-sponsored campaign fundraising gala. |
| 2013 | 57th Presidential Inauguration | Washington, D.C. | Kids' Inaugural Concert, hosted by First Lady Michelle Obama and Second Lady Dr. Jill Biden – Criss sang his own song "Not Alone", joined by the Soul Children of Chicago Archived January 18, 2019, at the Wayback Machine choir. He also accompanied Naya Rivera on guitar as she sang the hit "Valerie". Vice President Joe Biden Inaugural event – Criss sang "Teenage Dream" and Carole King's "One Fine Day". The Presidential Inaugural Ball – Criss performed the Disney song "When You Wish Upon a Star". |
| 2013 | Listen Up Tour | US, Canada & France | Criss headlined his first solo music tour, which visited 18 cities from May 29 – June 30. The set included songs from Glee, StarKid, his Human EP, and new material from his upcoming solo album. |
| 2013 | A Capitol Fourth | Washington, D.C. | Criss co-headlined the 4th of July celebration concert on the National Mall. |
| 2014 | Michael Feinstein's New Year's Eve at the Rainbow Room | New York | Criss co-sang with Michael Feinstein a medley of Frank Sinatra songs. |
| 2016 | Broadway Today with Darren Criss and Betsy Wolfe | Washington, D.C., N.Y.C. & Toronto | Criss co-headlined with Betsy Wolfe a Broadway-themed concert tour, accompanied by the National Symphony Orchestra, conducted by Steven Reineke. Performances were held at The Kennedy Center, Carnegie Hall, and Roy Thomson Hall. |
| 2016 | The Little Mermaid in Concert | Los Angeles | Criss co-headlined the concert at the Hollywood Bowl, playing the part of "Prince Eric". |
| Note: This is a selection of Criss' musical performances, not a complete list. |
