| Res. | Record | Opponent | Method | Event | Date | Round | Time | Location | Notes |
| Win | 29–2 (1) | Sara Collins | Submission (rear-naked choke) | PFL Lyon: Nemkov vs. Ferreira | December 13, 2025 | 3 | 2:55 | Décines-Charpieu, France | Won the inaugural PFL Women's Featherweight World Championship. |
| Win | 28–2 (1) | Larissa Pacheco | Decision (unanimous) | PFL Super Fights: Battle of the Giants | October 19, 2024 | 5 | 5:00 | Riyadh, Saudi Arabia | Won the symbolic PFL Super Fights Women's Featherweight Championship. |
| Win | 27–2 (1) | Cat Zingano | TKO (punches) | Bellator 300 | October 7, 2023 | 1 | 4:01 | San Diego, California, United States | Defended the Bellator Women's Featherweight World Championship. |
| Win | 26–2 (1) | Arlene Blencowe | Decision (unanimous) | Bellator 279 | April 23, 2022 | 5 | 5:00 | Honolulu, Hawaii, United States | Defended the Bellator Women's Featherweight World Championship. Cyborg was deducted one point in round 1 due to an illegal knee. Broke the record for the most consecutive Bellator Women's Featherweight World Championship title defenses (4). |
| Win | 25–2 (1) | Sinead Kavanagh | KO (punches) | Bellator 271 | November 12, 2021 | 1 | 1:32 | Hollywood, Florida, United States | Defended the Bellator Women's Featherweight World Championship. |
| Win | 24–2 (1) | Leslie Smith | TKO (punches) | Bellator 259 | May 21, 2021 | 5 | 4:51 | Uncasville, Connecticut, United States | Defended the Bellator Women's Featherweight World Championship. |
| Win | 23–2 (1) | Arlene Blencowe | Submission (rear-naked choke) | Bellator 249 | October 15, 2020 | 2 | 2:36 | Uncasville, Connecticut, United States | Defended the Bellator Women's Featherweight World Championship. |
| Win | 22–2 (1) | Julia Budd | TKO (punches) | Bellator 238 | January 25, 2020 | 4 | 1:14 | Inglewood, California, United States | Won the Bellator Women's Featherweight World Championship. |
| Win | 21–2 (1) | Felicia Spencer | Decision (unanimous) | UFC 240 | July 27, 2019 | 3 | 5:00 | Edmonton, Alberta, Canada | |
| Loss | 20–2 (1) | Amanda Nunes | KO (punch) | UFC 232 | December 29, 2018 | 1 | 0:51 | Inglewood, California, United States | Lost the UFC Women’s Featherweight World Championship. |
| Win | 20–1 (1) | Yana Santos | TKO (punches) | UFC 222 | March 3, 2018 | 1 | 3:25 | Las Vegas, Nevada, United States | Defended the UFC Women’s Featherweight World Championship. |
| Win | 19–1 (1) | Holly Holm | Decision (unanimous) | UFC 219 | December 30, 2017 | 5 | 5:00 | Las Vegas, Nevada, United States | Defended the UFC Women’s Featherweight World Championship. Fight of the Night. |
| Win | 18–1 (1) | Tonya Evinger | TKO (knees) | UFC 214 | July 29, 2017 | 3 | 1:56 | Anaheim, California, United States | Won the vacant UFC Women’s Featherweight World Championship. |
| Win | 17–1 (1) | Lina Länsberg | TKO (punches) | UFC Fight Night: Cyborg vs. Länsberg | September 24, 2016 | 2 | 2:29 | Brasília, Brazil | Catchweight (140 lb) bout. |
| Win | 16–1 (1) | Leslie Smith | TKO (punches) | UFC 198 | May 14, 2016 | 1 | 1:21 | Curitiba, Brazil | Catchweight (140 lb) bout. |
| Win | 15–1 (1) | Daria Ibragimova | KO (punches) | Invicta FC 15 | January 16, 2016 | 1 | 4:58 | Costa Mesa, California, United States | Defended the Invicta FC Featherweight World Championship. Cyborg vacated the title on March 24, 2017. |
| Win | 14–1 (1) | Faith van Duin | TKO (knee to the body and punches) | Invicta FC 13 | July 9, 2015 | 1 | 0:45 | Las Vegas, Nevada, United States | Defended the Invicta FC Featherweight World Championship. Performance of the Night. |
| Win | 13–1 (1) | Charmaine Tweet | TKO (punches) | Invicta FC 11 | February 27, 2015 | 1 | 0:46 | Los Angeles, California, United States | Defended the Invicta FC Featherweight World Championship. Performance of the Night. |
| Win | 12–1 (1) | Marloes Coenen | TKO (punches and elbows) | Invicta FC 6 | July 13, 2013 | 4 | 4:10 | Kansas City, Missouri, United States | Won the inaugural Invicta FC Featherweight World Championship. |
| Win | 11–1 (1) | Fiona Muxlow | TKO (knees and punches) | Invicta FC 5 | April 5, 2013 | 1 | 3:46 | Kansas City, Missouri, United States | Invicta FC Featherweight world title eliminator. |
| NC | 10–1 (1) | Hiroko Yamanaka | NC (overturned) | Strikeforce: Melendez vs. Masvidal | December 17, 2011 | 1 | 0:16 | San Diego, California, United States | For the Strikeforce Women's Featherweight World Championship. Originally a TKO (punches) win for Cyborg; overturned and stripped of the title on January 6, 2012 after she tested positive for stanozolol. |
| Win | 10–1 | Jan Finney | KO (knee to the body) | Strikeforce: Fedor vs. Werdum | June 26, 2010 | 2 | 2:56 | San Jose, California, United States | Defended the Strikeforce Women's Featherweight World Championship. |
| Win | 9–1 | Marloes Coenen | TKO (punches) | Strikeforce: Miami | January 30, 2010 | 3 | 3:40 | Sunrise, Florida, United States | Defended the Strikeforce Women's Featherweight World Championship. |
| Win | 8–1 | Gina Carano | TKO (punches) | Strikeforce: Carano vs. Cyborg | August 15, 2009 | 1 | 4:59 | San Jose, California, United States | Won the inaugural Strikeforce Women's Featherweight World Championship. |
| Win | 7–1 | Hitomi Akano | TKO (punches) | Strikeforce: Shamrock vs. Diaz | April 11, 2009 | 3 | 0:35 | San Jose, California, United States | Catchweight (150 lb) bout; Cyborg missed weight. |
| Win | 6–1 | Yoko Takahashi | Decision (unanimous) | EliteXC: Heat | October 4, 2008 | 3 | 3:00 | Sunrise, Florida, United States | Catchweight (150 lb) bout. |
| Win | 5–1 | Shayna Baszler | TKO (punches) | EliteXC: Unfinished Business | July 26, 2008 | 2 | 2:48 | Stockton, California, United States | Catchweight (140 lb) bout. |
| Win | 4–1 | Marise Vitoria | TKO (stomps) | Storm Samurai 12 | November 25, 2006 | 1 | 1:27 | Curitiba, Brazil | |
| Win | 3–1 | Elaine Santiago | TKO (corner stoppage) | Storm Samurai 11 | May 21, 2006 | 1 | 2:46 | Curitiba, Brazil | |
| Win | 2–1 | Chris Schroeder | TKO (punches) | Storm Samurai 10 | January 28, 2006 | 1 | N/A | Curitiba, Brazil | |
| Win | 1–1 | Vanessa Porto | Decision (unanimous) | Storm Samurai 9 | November 20, 2005 | 3 | 5:00 | Curitiba, Brazil | |
| Loss | 0–1 | Erica Paes | Submission (kneebar) | Show Fight 2 | May 17, 2005 | 1 | 1:46 | São Paulo, Brazil | Featherweight debut. |