| No. | Result | Record | Opponent | Type | Round, time | Date | Location | Notes |
| 52 | Loss | 45–5–2 | Carl Thompson | RTD | 9 (12), 3:00 | 18 Jul 1998 | Ponds Forge, Sheffield, England | For WBO junior-heavyweight title |
| 51 | Loss | 45–4–2 | Carl Thompson | UD | 12 | 18 Apr 1998 | NYNEX Arena, Manchester, England | For WBO junior-heavyweight title |
| 50 | Loss | 45–3–2 | Joe Calzaghe | UD | 12 | 11 Oct 1997 | Sheffield Arena, Sheffield, England | For vacant WBO super-middleweight title |
| 49 | Win | 45–2–2 | Camilo Alarcon | KO | 4 (10) | 27 Mar 1997 | Aviation Club Tennis Centre, Dubai, UAE | |
| 48 | Win | 44–2–2 | Luis Dionisio Barrera | KO | 5 (10), 0:42 | 19 Oct 1996 | Stadium Indoor Halls Complex, Cairo, Egypt | |
| 47 | Loss | 43–2–2 | Steve Collins | SD | 12 | 9 Sep 1995 | Páirc Uí Chaoimh, Cork, Ireland | For WBO super-middleweight title |
| 46 | Win | 43–1–2 | Jose Ignacio Barruetabena | KO | 1 (10), 0:55 | 29 Jul 1995 | Whitley Bay, England | |
| 45 | Win | 42–1–2 | Bruno Ruben Godoy | TKO | 1 (10) | 27 May 1995 | King's Hall, Belfast, Northern Ireland | |
| 44 | Loss | 41–1–2 | Steve Collins | UD | 12 | 18 Mar 1995 | Green Glens Arena, Millstreet, Ireland | Lost WBO super-middleweight title |
| 43 | Win | 41–0–2 | Henry Wharton | UD | 12 | 10 Dec 1994 | G-Mex Centre, Manchester, England | Retained WBO super-middleweight title |
| 42 | Win | 40–0–2 | Dan Schommer | UD | 12 | 15 Oct 1994 | Superbowl, Sun City, South Africa | Retained WBO super-middleweight title |
| 41 | Win | 39–0–2 | Sam Storey | TKO | 7 (12), 1:00 | 27 Aug 1994 | International Arena, Cardiff, Wales | Retained WBO super-middleweight title |
| 40 | Win | 38–0–2 | Mauricio Amaral | UD | 12 | 9 Jul 1994 | Earls Court Exhibition Centre, London, England | Retained WBO super-middleweight title |
| 39 | Win | 37–0–2 | Ray Close | SD | 12 | 21 May 1994 | King's Hall, Belfast, Northern Ireland | Retained WBO super-middleweight title |
| 38 | Win | 36–0–2 | Graciano Rocchigiani | UD | 12 | 5 Feb 1994 | Deutschlandhalle, Berlin, Germany | Retained WBO super-middleweight title |
| 37 | Draw | 35–0–2 | Nigel Benn | SD | 12 | 9 Oct 1993 | Old Trafford, Manchester, England | Retained WBO super-middleweight title;For WBC super-middleweight title |
| 36 | Draw | 35–0–1 | Ray Close | SD | 12 | 15 May 1993 | Exhibition and Conference Centre, Glasgow, Scotland | Retained WBO super-middleweight title |
| 35 | Win | 35–0 | Lindell Holmes | UD | 12 | 20 Feb 1993 | Earls Court Exhibition Centre, London, England | Retained WBO super-middleweight title |
| 34 | Win | 34–0 | Juan Carlos Gimenez | UD | 12 | 28 Nov 1992 | G-Mex Centre, Manchester, England | Retained WBO super-middleweight title |
| 33 | Win | 33–0 | Tony Thornton | UD | 12 | 19 Sep 1992 | Exhibition and Conference Centre, Glasgow, Scotland | Retained WBO super-middleweight title |
| 32 | Win | 32–0 | Ron Essett | UD | 12 | 27 Jun 1992 | Quinta do Lago Hotel, Almancil, Portugal | Retained WBO super-middleweight title |
| 31 | Win | 31–0 | John Jarvis | KO | 3 (12), 1:50 | 25 Apr 1992 | G-Mex Centre, Manchester, England | Retained WBO super-middleweight title |
| 30 | Win | 30–0 | Thulani Malinga | SD | 12 | 1 Feb 1992 | National Exhibition Centre, Birmingham, England | Retained WBO super-middleweight title |
| 29 | Win | 29–0 | Michael Watson | TKO | 12 (12), 0:29 | 21 Sep 1991 | White Hart Lane, London, England | Won vacant WBO super-middleweight title |
| 28 | Win | 28–0 | Michael Watson | MD | 12 | 22 Jun 1991 | Earls Court Exhibition Centre, London, England | Retained WBO middleweight title |
| 27 | Win | 27–0 | Gary Stretch | TKO | 6 (12), 1:56 | 18 Apr 1991 | Olympia Grand Hall, London, England | Retained WBO middleweight title |
| 26 | Win | 26–0 | Dan Sherry | TD | 10 (12), 2:11 | 23 Feb 1991 | Brighton Centre, Brighton, England | Retained WBO middleweight title;Split TD: Sherry unable to continue after a headbutt by Eubank |
| 25 | Win | 25–0 | Nigel Benn | TKO | 9 (12), 2:56 | 18 Nov 1990 | National Exhibition Centre, Birmingham, England | Won WBO middleweight title |
| 24 | Win | 24–0 | Reginaldo Dos Santos | KO | 1 (10), 0:20 | 22 Sep 1990 | Royal Albert Hall, London, England | |
| 23 | Win | 23–0 | Kid Milo | TKO | 8 (12) | 5 Sep 1990 | Brighton Centre, Brighton, England | Retained WBC International middleweight title |
| 22 | Win | 22–0 | Eduardo Domingo Contreras | UD | 12 | 25 Apr 1990 | Brighton Centre, Brighton, England | Retained WBC International middleweight title |
| 21 | Win | 21–0 | Hugo Antonio Corti | TKO | 8 (12), 0:46 | 6 Mar 1990 | York Hall, London, England | Won WBC International middleweight title |
| 20 | Win | 20–0 | Denys Cronin | TKO | 3 (8), 1:15 | 16 Jan 1990 | STAR Centre, Cardiff, Wales | |
| 19 | Win | 19–0 | Jose Carlos da Silva | KO | 6 (8) | 20 Dec 1989 | Kirkby Leisure Centre, Liverpool, England | |
| 18 | Win | 18–0 | Johnny Melfah | KO | 4 (8) | 5 Nov 1989 | Royal Albert Hall, London, England | |
| 17 | Win | 17–0 | Jean-Noel Camara | TKO | 2 (8) | 24 Oct 1989 | York Hall, London, England | |
| 16 | Win | 16–0 | Ron Malek | TKO | 5 (8), 1:20 | 4 Oct 1989 | Festival Hall, Basildon, England | |
| 15 | Win | 15–0 | Les Wisniewski | TKO | 2 (8), 1:07 | 28 Jun 1989 | International Centre, Brentwood, England | |
| 14 | Win | 14–0 | Randy Smith | PTS | 10 | 26 May 1989 | York Hall, London, England | |
| 13 | Win | 13–0 | Franky Moro | PTS | 8 | 1 Mar 1989 | York Hall, London, England | |
| 12 | Win | 12–0 | Anthony Logan | PTS | 8 | 8 Feb 1989 | Royal Albert Hall, London, England | |
| 11 | Win | 11–0 | Simon Collins | TKO | 4 (8), 2:22 | 31 Jan 1989 | York Hall, London, England | |
| 10 | Win | 10–0 | Steve Aquilina | TKO | 4 (6), 2:40 | 18 May 1988 | Guildhall, Portsmouth, England | |
| 9 | Win | 9–0 | Greg George | TKO | 5 (8), 1:25 | 4 May 1988 | Olympia Grand Hall, London, England | |
| 8 | Win | 8–0 | Michael Justin | TKO | 5 (8) | 26 Apr 1988 | Town Hall, Hove, England | |
| 7 | Win | 7–0 | Winston Burnett | PTS | 6 | 7 Mar 1988 | Town Hall, Hove, England | |
| 6 | Win | 6–0 | Darren Parker | TKO | 1 (6) | 15 Feb 1988 | Effingham Park Country Club, Copthorne, England | |
| 5 | Win | 5–0 | James Canty | UD | 4 | 25 Mar 1987 | Resorts Casino Hotel, Atlantic City, New Jersey, US | |
| 4 | Win | 4–0 | Eric Holland | UD | 4 | 25 Feb 1986 | Tropicana, Atlantic City, New Jersey, US | |