| Year | Title | Role | Notes |
| 1981 | Bosom Buddies | Bob the Comic | Episode: "The Show Must Go On" |
| 1983 | The Greatest American Hero | Rook | Episode: "Wizards and Warlocks"[citation needed] |
| 1985 | New Love, American Style | Various | 4 episodes |
| 1986 | It's a Living | Dr. Bartlett | Episode: "The Doctor Danny Show"[citation needed] |
| 1987–1995 | Full House | Danny Tanner | Main role; 192 episodes |
| 1989–1997 | America's Funniest Home Videos | Himself/host | 191 episodes, guest-hosted 2 episode in 2009 and in 2019; cameo in 2015 |
| 1989 | The All-New Mickey Mouse Club | Danny Tanner | Episode: "Guest Day" |
| 1992 | Quantum Leap | Macklyn "Mack" MacKay | Episode: "Stand Up – April 30, 1959" |
| 1992 | To Grandmother's House We Go | Win-O-Lotto Lottery Host | Movie; uncredited |
| 1994 | Father and Scout | Spencer Paley | Movie; also executive producer |
| 1995 | Saturday Night Live | Himself (host) | Episode: "Bob Saget/TLC" |
| 1996 | For Hope | | Movie; director and executive producer |
| 1997 | Jitters | | Movie; director |
| 2000 | Becoming Dick | Bob | Movie (uncredited); also director |
| 2000 | The Norm Show | Mr. Atkitson | Episode: "Norm vs. Schoolin ; also director[citation needed] |
| 2001–2002 | Raising Dad | Matt Stewart | 22 episodes |
| 2004 | Joey | Himself | Episode: "Joey and the Road Trip"[citation needed] |
| 2004 | Huff | Butch | Episode: "Flashpants" |
| 2005 | Listen Up | Mitch | Episode: "Coach Potato" |
| 2005–2010 | Entourage | Himself | 4 Episodes |
| 2005–2014 | How I Met Your Mother | Ted Mosby (in 2030) | 208 episodes; Voice-over narration |
| 2006–2008 | 1 vs. 100 | Himself/host | Game show (28 episodes) |
| 2006 | Casper's Scare School | Dash (voice) | Movie; voice role |
| 2006 | Law & Order: Special Victims Unit | Glenn Cheales | Episode: "Choreographed" |
| 2008 | The Life & Times of Tim | Party Marty | Episode: "Mugger/Cin City"; voice role |
| 2008 | The Comedy Central Roast of Bob Saget | Himself | Special[citation needed] |
| 2009 | Surviving Suburbia | Steve Patterson | 13 episodes |
| 2010 | Strange Days with Bob Saget | Himself/host | 6 episodes |
| 2011 | Law & Order: LA | Adam Brennan | Episode: "Van Nuys" |
| 2011 | Louie | Himself | Episode: "Oh Louie/Tickets" |
| 2014 | Super Fun Night | Mr. Porter Warner | Episode: "Cookie Prom" |
| 2014 | Legit | Himself | Episode: "Licked" |
| 2015, 2016 | Grandfathered | Himself/Ronnie | Episode: "Pilot"/Episode: "The Sat Pack" |
| 2016 | Robot Chicken | Mike O'Malley, Galactus, Cable Guy (voices) | Episode: "The Unnamed One" |
| 2016–2020 | Fuller House | Danny Tanner | Recurring role; 15 episodes |
| 2017 | Michael Bolton's Big, Sexy Valentine's Day Special | Himself | Variety special |
| 2017 | Nightcap | Himself | Episode: "Bringing Up Baby" |
| 2018 | The Good Cop | Richie Knight | Episode: "Did the TV Star Do It?" |
| 2018 | Shameless | Father D'Amico | Episode: "Face It, You're Gorgeous" |
| 2018 | Bumping Mics with Jeff Ross & Dave Attell | Himself | 1 episode |
| 2019 | Videos After Dark | Himself/host | 2 episodes |
| 2019 | Historical Roasts | Abraham Lincoln | Episode: "Abraham Lincoln"[citation needed] |
| 2019 | Nashville Squares | Himself/host | 10 episodes[citation needed] |
| 2019–2021 | To Tell the Truth | Himself | 3 episodes |
| 2020 | The Masked Singer | Squiggly Monster | Eliminated after second appearance |
| 2021 | Nickelodeon's Unfiltered | Himself | Episode: "Dreaming of an Awful Waffle!" |
| 2022 | Phat Tuesdays: The Era Of Hip Hop Comedy | Himself | Documentary series; posthumous release |
| 2022 | Welcome Home Nikki Glaser? | Himself | Episode: "Love Shack Baby?"; posthumous release |