| No. | Result | Record | Opponent | Type | Round, time | Date | Location | Notes |
| 49 | Loss | 40–9 | Alfonso Gómez | TKO | 7 (10), 2:12 | Jul 14, 2007 | Boardwalk Hall, Atlantic City, New Jersey, U.S. | |
| 48 | Loss | 40–8 | Carlos Baldomir | TKO | 9 (12), 2:50 | Jul 22, 2006 | Boardwalk Hall, Atlantic City, New Jersey, U.S. | Lost IBA welterweight title;For WBC and The Ring welterweight titles |
| 47 | Win | 40–7 | Thomas Damgaard | TKO | 11 (12), 2:54 | Jan 28, 2006 | Boardwalk Hall, Atlantic City, New Jersey, U.S. | Won vacant IBA welterweight title |
| 46 | Loss | 39–7 | Floyd Mayweather Jr. | RTD | 6 (12), 3:00 | Jun 25, 2005 | Boardwalk Hall, Atlantic City, New Jersey, U.S. | Lost WBC super lightweight title |
| 45 | Win | 39–6 | Jesse James Leija | KO | 5 (12), 1:48 | Jan 29, 2005 | Boardwalk Hall, Atlantic City, New Jersey, U.S. | Retained WBC super lightweight title |
| 44 | Win | 38–6 | Leonard Doroftei | KO | 2 (12), 2:55 | Jul 24, 2004 | Boardwalk Hall, Atlantic City, New Jersey, U.S. | Retained WBC super lightweight title |
| 43 | Win | 37–6 | Gianluca Branco | UD | 12 | Jan 24, 2004 | Boardwalk Hall, Atlantic City, New Jersey, U.S. | Won vacant WBC super lightweight title |
| 42 | Win | 36–6 | Micky Ward | UD | 10 | Jun 7, 2003 | Boardwalk Hall, Atlantic City, New Jersey, U.S. | |
| 41 | Win | 35–6 | Micky Ward | UD | 10 | Nov 23, 2002 | Boardwalk Hall, Atlantic City, New Jersey, U.S. | |
| 40 | Loss | 34–6 | Micky Ward | MD | 10 | May 18, 2002 | Mohegan Sun Arena, Montville, Connecticut, U.S. | |
| 39 | Win | 34–5 | Terron Millett | TKO | 4 (10), 2:23 | Jan 26, 2002 | The Theater at Madison Square Garden, New York City, New York, U.S. | |
| 38 | Loss | 33–5 | Oscar De La Hoya | TKO | 5 (12), 1:16 | Mar 24, 2001 | MGM Grand Garden Arena, Paradise, Nevada, U.S. | |
| 37 | Win | 33–4 | Joe Hutchinson | UD | 10 | Sep 8, 2000 | Molson Centre, Montreal, Quebec, Canada | |
| 36 | Win | 32–4 | Eric Jakubowski | TKO | 2 (10), 0:40 | Apr 29, 2000 | Madison Square Garden, New York City, New York, U.S. | |
| 35 | Win | 31–4 | Joey Gamache | KO | 2 (10), 0:41 | Feb 26, 2000 | Madison Square Garden, New York City, New York, U.S. | |
| 34 | Win | 30–4 | Reyes Munoz | TKO | 1 (10), 3:09 | Aug 14, 1999 | Foxwoods Resort Casino, Ledyard, Connecticut, U.S. | |
| 33 | Loss | 29–4 | Ivan Robinson | UD | 10 | Dec 12, 1998 | Etess Arena, Atlantic City, New Jersey, U.S. | |
| 32 | Loss | 29–3 | Ivan Robinson | SD | 10 | Aug 22, 1998 | Boardwalk Hall, Atlantic City, New Jersey, U.S. | |
| 31 | Loss | 29–2 | Angel Manfredy | TKO | 8 (10), 2:57 | Jan 17, 1998 | Boardwalk Hall, Atlantic City, New Jersey, U.S. | |
| 30 | Win | 29–1 | Gabriel Ruelas | TKO | 5 (12), 2:22 | Oct 4, 1997 | Boardwalk Hall, Atlantic City, New Jersey, U.S. | Retained IBF junior lightweight title |
| 29 | Win | 28–1 | Calvin Grove | RTD | 7 (10), 3:00 | May 4, 1997 | Circus Maximus Showroom, Atlantic City, New Jersey, U.S. | |
| 28 | Win | 27–1 | Tracy Harris Patterson | UD | 12 | Feb 22, 1997 | Convention Hall, Atlantic City, New Jersey, U.S. | Retained IBF junior lightweight title |
| 27 | Win | 26–1 | Feliciano Correa | KO | 3 (10), 2:05 | Jul 11, 1996 | Madison Square Garden, New York City, New York, U.S. | |
| 26 | Win | 25–1 | Wilson Rodriguez | KO | 6 (12), 2:16 | Mar 23, 1996 | The Theater at Madison Square Garden, New York City, New York, U.S. | Retained IBF junior lightweight title |
| 25 | Win | 24–1 | Tracy Harris Patterson | UD | 12 | Dec 15, 1995 | Madison Square Garden, New York City, New York, U.S. | Won IBF junior lightweight title |
| 24 | Win | 23–1 | Carlos Vergara | TKO | 1 (10), 0:57 | Oct 7, 1995 | Convention Hall, Atlantic City, New Jersey, U.S. | |
| 23 | Win | 22–1 | Barrington Francis | TKO | 6 (10) | Jul 13, 1995 | Circus Maximus Showroom, Atlantic City, New Jersey, U.S. | |
| 22 | Win | 21–1 | Tialano Tovar | KO | 1 (10), 1:41 | Apr 22, 1995 | Bally's Park Place, Atlantic City, New Jersey, U.S. | |
| 21 | Win | 20–1 | Roman Smolenkov | KO | 1 | Mar 9, 1995 | Martinihal, Groningen, Netherlands | |
| 20 | Win | 19–1 | Jose Sanabria | UD | 12 | Nov 22, 1994 | Meadowlands Exposition Center, Secaucus, New Jersey, U.S. | Retained USBA junior lightweight title |
| 19 | Win | 18–1 | Richard Salazar | TKO | 10 (12), 2:29 | Aug 16, 1994 | The Blue Horizon, Philadelphia, Pennsylvania, U.S. | Retained USBA junior lightweight title |
| 18 | Win | 17–1 | Pete Taliaferro | TKO | 1 (12), 3:00 | Jun 28, 1994 | Meadowlands Exposition Center, Secaucus, New Jersey, U.S. | Won USBA junior lightweight title |
| 17 | Win | 16–1 | Darrell Singleton | TKO | 1 (8), 0:41 | May 6, 1994 | Convention Hall, Atlantic City, New Jersey, U.S. | |
| 16 | Win | 15–1 | Leon Bostic | MD | 8 | Jan 8, 1994 | Friar Tuck Inn, Catskill, New York, U.S. | |
| 15 | Win | 14–1 | Glenn Irizarry | TKO | 1 | Nov 11, 1993 | Huntington Hilton Hotel, Melville, New York, U.S. | |
| 14 | Win | 13–1 | Derek Francis | KO | 1 | Oct 23, 1993 | Sands Casino Hotel, Atlantic City, New Jersey, U.S. | |
| 13 | Win | 12–1 | Luis Guzman | KO | 1 | Aug 24, 1993 | Merv Griffin's Resorts, Atlantic City, New Jersey, U.S. | |
| 12 | Win | 11–1 | Robert Scott | KO | 1 | Jul 30, 1993 | Ramada Hotel, New York City, New York, U.S. | |
| 11 | Win | 10–1 | Christino Suero | KO | 3 (8), 1:55 | Jun 20, 1993 | Harrah's Marina Hotel Casino, Atlantic City, New Jersey, U.S. | |
| 10 | Win | 9–1 | Clifford Hicks | KO | 3 | May 15, 1993 | Memorial High School, Brick Township, New Jersey, U.S. | |
| 9 | Win | 8–1 | Curtis Mathis | TKO | 3 | Apr 7, 1993 | Robert Treat Hotel, Newark, New Jersey, U.S. | |
| 8 | Win | 7–1 | Plamen Gechev | TKO | 1 | Mar 23, 1993 | Rotterdam Ahoy Sportpaleis, Rotterdam, Netherlands | |
| 7 | Loss | 6–1 | King Solomon | SD | 6 | Nov 17, 1992 | The Blue Horizon, Philadelphia, Pennsylvania, U.S. | |
| 6 | Win | 6–0 | Joe Lafontant | UD | 6 | May 15, 1992 | Trump Taj Mahal, Atlantic City, New Jersey, U.S. | |
| 5 | Win | 5–0 | Antonio Gonzalez | TKO | 1 (4), 1:35 | Apr 22, 1992 | Meadowlands Arena, East Rutherford, New Jersey, U.S. | |
| 4 | Win | 4–0 | Francisco Aguiano | TKO | 1 | Oct 22, 1991 | The Blue Horizon, Philadelphia, Pennsylvania, U.S. | |
| 3 | Win | 3–0 | Richard De Jesus | TKO | 1 (4), 0:28 | Aug 2, 1991 | Quality Inn Hotel, Newark, New Jersey, U.S. | |
| 2 | Win | 2–0 | Luis Melendez | KO | 1 (4), 0:19 | Jul 9, 1991 | The Blue Horizon, Philadelphia, Pennsylvania, U.S. | |
| 1 | Win | 1–0 | Jose Gonzales | TKO | 3 (4), 1:27 | Jun 10, 1991 | Meadowlands Exposition Center, Secaucus, New Jersey, U.S. | |