| Game no. | Air date | Final score | Cumulative winnings | Notes |
| 1 | November 17 | $31,600* | $31,600 | |
| 2 | November 18 | $33,800 | $65,400 | |
| 3 | November 19 | $44,800 | $110,200 | |
| 4 | November 22 | $45,400 | $155,600 | |
| 5 | November 23 | $14,800 | $170,400 | First game in which she failed to give a correct response in Final Jeopardy! round. |
| 6 | November 24 | $37,400 | $207,800 | |
| 7 | November 25 | $50,000 | $257,800 | |
| 8 | November 26 | $37,400 | $295,200 | |
| 9 | November 29 | $47,000 | $342,200 | |
| 10 | November 30 | $38,000* | $380,200 | |
| 11 | December 1 | $41,000 | $421,200 | |
| 12 | December 2 | $61,800 | $483,000 | |
| 13 | December 3 | $53,400 | $536,400 | |
| 14 | December 20 | $34,800* | $571,200 | Regular season play resumed after the 2021 Professors Tournament. |
| 15 | December 21 | $35,000 | $606,200 | |
| 16 | December 22 | $25,200 | $631,400 | Second game in which she failed to give a correct response in Final Jeopardy! round. |
| 17 | December 23 | $56,000 | $687,400 | |
| 18 | December 24 | $19,400 | $706,800 | Third game in which she failed to give a correct response in Final Jeopardy! round. |
| 19 | December 27 | $38,400 | $745,200 | |
| 20 | December 28 | $23,400 | $768,600 | |
| 21 | December 29 | $37,400 | $806,000 | Set a record for longest win streak by a female player |
| 22 | December 30 | $25,600* | $831,600 | |
| 23 | December 31 | $24,000 | $855,600 | Fourth game in which she failed to give a correct response in Final Jeopardy! round. |
| 24 | January 3 | $42,000 | $897,600 | |
| 25 | January 4 | $20,400 | $918,000 | Fifth game in which she failed to give a correct response in Final Jeopardy! round. |
| 26 | January 5 | $32,000 | $950,000 | |
| 27 | January 6 | $27,400* | $977,400 | |
| 28 | January 7 | $42,200 | $1,019,600 | Became fourth Jeopardy! contestant to win $1 million in regular gameplay winnings |
| 29 | January 10 | $15,800 | $1,035,400 | Sixth game in which she failed to give a correct response in Final Jeopardy! round. |
| 30 | January 11 | $22,400 | $1,057,800 | Seventh game in which she failed to give a correct response in Final Jeopardy! round. |
| 31 | January 12 | $11,000 | $1,068,800 | Eighth game in which she failed to give a correct response in Final Jeopardy! round. |
| 32 | January 13 | $32,800 | $1,101,600 | |
| 33 | January 14 | $10,200 | $1,111,800 | Ninth game in which she failed to give a correct response in Final Jeopardy! round, lowest single day total. |
| 34 | January 17 | $36,800 | $1,148,600 | |
| 35 | January 18 | $15,400 | $1,164,000 | Tenth game in which she failed to give a correct response in Final Jeopardy! round. |
| 36 | January 19 | $17,800 | $1,181,800 | Eleventh game in which she failed to give a correct response in Final Jeopardy! round. |
| 37 | January 20 | $71,400 | $1,253,200 | |
| 38 | January 21 | $54,000 | $1,307,200 | |
| 39 | January 24 | $12,600 | $1,319,800 | Twelfth game in which she failed to give a correct response in Final Jeopardy! round. Passed Matt Amodio for second-longest winning streak in regular play, behind Ken Jennings. |
| 40 | January 25 | $63,000 | $1,382,800 | |
| 41 | January 26 | $19,600‡ | $1,384,800 | Defeated by challenger Rhone Talsma, who finished the game with $29,600. At the end of the first round, Schneider had $7,200; Talsma had $3,400; and challenger Janice Hawthorne Timm had $2,000. At the end of Double Jeopardy!, Schneider was in the lead with $27,600; Talsma was in second place with $17,600; and Hawthorne Timm was in third with $3,200. Schneider gave the wrong answer and finished second. She was awarded $2,000. This was the 13th game in which she failed to give a correct response in the Final Jeopardy! round. |
| Yellow background denotes game which was not a runaway (lead going into Final Jeopardy! round could not guarantee a win). |
| ‡ Red background denotes game in which Schneider is defeated. |
