| Year | Title | Role | Notes |
| 1999–2000 | Early Edition | Susan Schwartz | 2 episodes |
| 2003 | Law & Order: Special Victims Unit | Stephanie Grayson | Episode: "Rotten" |
| 2005 | Law & Order: Special Victims Unit | Jamie Callahan | Episode: "Goliath" |
| 2006 | Conviction | Donna Thatcher | Episode: "True Love" |
| 2008 | Law & Order | Attorney Parrish | Episode: "Misbegotten" |
| 2008 | Mad Men | Petra Colson | Episode: "A Night to Remember" |
| 2010 | Law & Order: Criminal Intent | Agent Stahl | 2 episodes |
| 2010–2014 | Louie | Sandra/Louie's Mother | 4 episodes |
| 2011 | NCIS | Dr. Ellen Gracey | Episode: "Out of the Frying Pan" |
| 2011 | The Paul Reiser Show | Claire | Series regular, 7 episodes |
| 2011 | House | Darrien | Episode: "After Hours" |
| 2011 | The Protector | Arlene Duncan | Episode: "Spoon" |
| 2011 | Happily Divorced | Audrey | Episode: "Someone Wants Me" |
| 2011 | Curb Your Enthusiasm | Jane Cohen | Episode: "The Bi-Sexual" |
| 2011 | Prime Suspect | Alice Paget | Episode: "The Great Wall of Silence" |
| 2011–2014 | Revenge | Dr. Michelle Banks | 3 episodes |
| 2012 | House of Lies | Janelle Winter | Episode: "Microphallus" |
| 2012 | Private Practice | Melissa | Episode: "Too Much" |
| 2012 | Retired at 35 | Kat | Episode: "The Proposal" |
| 2013 | Vegas | Karen Schultz | Episode: "From This Day Forward" |
| 2013 | Clear History | Nathan's Wife | Television film |
| 2014–2019 | Transparent | Sarah Pfefferman | Series regular; 38 episodes Nominated—Screen Actors Guild Award for Outstanding Performance by an Ensemble in a Comedy Series (2015)Nominated—Gold Derby Award for Best Comedy Supporting Actress (2016) |
| 2015 | Married | Harper's Mom | Episode: "Koreatown" |
| 2016 | People of Earth | Debbie Schultz | Episode: "Acceptance" |
| 2016–2018 | Trollhunters: Tales of Arcadia | Barbara Lake (voice) | 37 episodes |
| 2017 | Room 104 | Joan Teakins | Episode: "Phoenix" |
| 2018 | Grey's Anatomy | Morgan | Episode: "(Don’t Fear) the Reaper" |
| 2018 | Alone Together | Camille | Episode: "Dinner Party" |
| 2018 | LA to Vegas | Patricia | 3 episodes |
| 2019 | Sneaky Pete | Lorraine Sheffield | Recurring, 5 episodes |
| 2019 | The Twilight Zone | Anne Storck | Episode: "The Blue Scorpion" |
| 2019–2022 | The Handmaid's Tale | Mrs. Mackenzie | 3 episodes |
| 2019 | She-Ra and the Princesses of Power | Octavia (voice) | Episode: "Boys' Night Out" |
| 2020 | Kipo and the Age of Wonderbeasts | Dr. Emilia (voice) | 17 episodes |
| 2020 | Little Birds | Vanessa Savage | 3 episodes |
| 2020–2023 | Your Honor | Nancy Costello | Recurring role (season 1 & 2) |
| 2021 | Q-Force | (voice) | Episode: "Backache Mountain" |
| 2021 | The Premise | Trish | Episode: "Moment of Silence" |
| 2021–2023 | The Croods: Family Tree | Ugga Crood (voice) | 49 episodes |
| 2022 | Minx | Bridget Westbury | 3 episodes |
| 2022 | Chivalry | Mia | 2 episodes |
| 2022 | We Baby Bears | Gail (voice) | Episode: "Tooth Fairy Tech" |
| 2022 | Gaslit | Lurleen Landry | Episode: "Tuffy" |
| 2022 | Ramy | Kendra | Episode: "American Life Coach" |
| 2024 | In the Know | Various voices | 4 episodes |
| 2025 | Law & Order: Special Victims Unit | Katharine Vernon | Episode: "First Light" |
| 2025 | Number 1 Happy Family USA | Donna (voice) | Episode: "Egypt Is On the Phone!" |