| Year | Title | Role | Notes |
| 1994–95 | My Brother and Me | Deonne Wilburn | Recurring cast |
| 2002–05 | Def Poetry Jam | Herself | Episode: "Episode " & "#5.8" |
| 2010 | Undateable | Herself | Main guest |
| 2011 | Independent Lens | Herself | Episode: "Deaf Jam" |
| 2012 | MTV's Hip Hop POV | Herself/Co-Host | Main co-host |
| Made | Herself/Made Coach | Episode: "Professional Actress: Rita" |
| 2013 | Big Evening Buzz | Herself/Panelist | Episode: "Dido" |
| Master of the Mix | Herself/Host | Main host: Season 3 |
| Big Morning Buzz Live | Herself/Panelist | Recurring panelist |
| 2015 | The View | Herself/Guest Co-Host | Episode: "Episode " |
| 2015–17 | Get Your Life | Herself | Main cast |
| 2016 | Comedy Knockout | Herself | Episode: "That Ass, Tho" |
| 2016–17 | Greatest Ever | Herself/Host | Main host |
| 2016–21 | Insecure | Tiffany DuBois | Recurring cast |
| 2017 | Hood Adjacent with James Davis | Herself | Episode: "Black Twitter" |
| @midnight | Herself | Episode: "Episode " & "#4.136" |
| Gay of Thrones | Herself | Episode: "The Sores of Whores" |
| 2017–20 | The Real | Herself/Co-Host | Guest co-host: Season 4, Main Co-Host: Season 6 |
| 2018 | Black-ish | Barbara | Recurring cast: Season 4 |
| Animals. | Tia/Waitress 1 (voice) | Episode: "Rats" |
| 2018–19 | Hip Hop Squares | Herself/Panelist | Recurring panelist: Season 5-6 |
| 2019 | Bring the Funny | Herself/Host | Main host |
| Camp Confessions | Herself | Episode: "Amanda Seales Makes Love to Spirit" |
| 2019–21 | To Tell the Truth | Herself/Panelist | Guest panelist: Season 4-5 & 7 |
| 2020 | Cooked with Cannabis | Herself | Episode: "High Holidays" |
| Floored | Herself/Guest Judge | Episode: "Beware the Bears" |
| BET Awards | Herself/Host | Main host |
| Hollywood Game Night | Herself/Celebrity Player | Episode: "Twitch & Shout" |
| Match Game | Herself/Contestant | Episode: "Episode " |
| 2021 | Fast Foodies | Herself | Episode: "Amanda Seales" |
| Finding Magic Mike | Herself | Episode: "A Talented Man" |
| 2022 | Real Husbands of Hollywood | Herself | Episode: "Wrestling While Black" |
| Everything's Gonna Be All White | Herself | Main guest |
| Inventions That Changed History | Herself | Recurring guest |
| Celebrity Game Face | Herself/Contestant | Episode: "Cedric the Entertainer Busts Kevin's Chops" |
| Wheel of Fortune | Herself/Contestant | Episode: "Amanda Seales, Snoop Dogg, Mark Duplass" |
| Mickey Mouse Funhouse | Annie the Giant (voice) | Recurring cast: Season 1 |
| Sherman's Showcase | Faith Evans | Episode: "Fashion!" |
| 2022–23 | 25 Words or Less | Herself/Contestant | Recurring contestant: Season 3-5 |
| 2022–24 | Pictionary | Herself/Team Captain | Recurring Team Captain: Season 1, Guest Team Captain: Season 2 |
| 2023 | See It Loud: The History of Black Television | Herself | Recurring guest |
| The $100,000 Pyramid | Herself/Celebrity Player | Episode: "Will Sasso vs. Amanda Seales and Dulé Hill vs. Francia Raisa" |
| Name That Tune | Herself/Contestant | Episode: "Lightning & Glitter!" |
| Celebrity Squares | Herself/Contestant | Recurring guest |
| Celebrity Jeopardy! | Herself/Contestant | Episode: "Quarter Final : Kyra Sedgwick, Mo Rocca and Amanda Seales" |
| Crimson Hearts Collide | Kelsey | Main cast |
