| Name | Class year | Notability | Reference(s) |
| 2 Chainz | | American rapper, played basketball for two seasons while attending | |
| Ralph Abernathy | 1950 | civil rights leader and minister | |
| Reggie Barlow | 1996 | former professional football wide receiver and current head football coach of the DC Defenders | |
| Brad Baxter | | former football running back who played 6 seasons in the NFL for the New York Jets (1989–1995) | |
| Clarence Carter | 1960 | soul singer and musician, best known for his hits "Strokin , "Patches", and "Snatching It Back" | |
| London "Deelishis" Charles | | winner of reality show Flavor of Love 2 | |
| Michael Coe | 2007 | NFL defensive back | |
| James Daniel | 1974 | tight ends coach for the Pittsburgh Steelers | |
| Steven Daniel | 1993 | actor and comedian | |
| Thomas Figures | 1966 | first African American assistant district attorney and assistant United States Attorney | |
| Fred Gray | | attorney who represented Rosa Parks during the Montgomery bus boycott | |
| Erskine Hawkins | | jazz musician, composer of "Tuxedo Junction" | |
| Dorothy E. Hayes | | early Black graphic designer, educator, and curator | |
| Tarvaris Jackson | 2006 | professional football player, quarterback for the Seattle Seahawks | |
| Terren Jones | 2012 | NFL offensive lineman | |
| Lil Yachty | | vocalist | |
| Kevin Loder | 1981 | former NBA player for the Kansas City Kings and San Diego Clippers | |
| Manny Martin | | former NFL defensive back for the Buffalo Bills during the 1990s | |
| Tangi Miller | 1993 | actress with The WB's Felicity | |
| Travis Pearson | | former Arena Football League player | |
| Eddie Robinson | | former linebacker, who played 11 seasons in the NFL for the Houston Oilers, Jacksonville Jaguars, Tennessee Titans, and the Buffalo Bills; started for the Titans in Super Bowl XXXIV | |
| Quinton Ross | | member of the Alabama Senate, representing the 26th District | |
| Eugene Sawyer | 1956 | politician and businessman, Mayor of Chicago 1987–1989 | |
| Dr. Fred Shuttlesworth | | civil rights leader and minister, co-founder of the Southern Christian Leadership Council | |
| Rickey Smiley | 1992 | comedian and actor | |
| Felix Stallings, Jr. | | electronica artist, producer, and DJ Felix da housecat | |
| Troy Stubbs | | Member of the Alabama House of Representatives | |
| Jessie Tompkins | 1998 | former nationally ranking athlete in track and field; head coach for the East Montgomery Track Club; first African America student to challenge the State of Alabama’s White-only, race-based scholarships | |
| Fred Wesley | | jazz and funk trombonist, best known for his work with James Brown in the 1960s and 1970s | |
| Jesse White | | 37th Secretary of State of Illinois | |
| Doug Williams | 1995 | comedian and actor | |
| Marcus Winn | | former linebacker for the Edmonton Eskimos and the Winnipeg Blue Bombers of the Canadian Football League | |