| Date | Flight number | Description |
| 13 June 1964 | 3277 | Vickers Viscount registration CF-THT was damaged beyond economical repair when it crash-landed at Toronto Airport after the failure of two engines on approach. |
| 19 May 1967 | N/A | McDonnell Douglas DC-8-54F CF-TJM crashed and burned on a training flight while making a three-engine landing at Ottawa, Ontario. All three crew members were killed. There were no passengers on the flight. |
| 11 September 1968 | 303 | A Vickers Viscount was hijacked by Charles Lavern Beasley, a Texas native and activist, who demanded that the plane be taken to Cuba. It made a successful emergency landing in Montreal, with no injuries reported. It was the first hijacking of its kind in Canadian history. |
| 7 April 1969 | N/A | Vickers Viscount registration CF-THK was damaged beyond economic repair by a fire which occurred on takeoff from Sept-Îles Airport. The aircraft landed back at Sept-Îles, but one passenger was killed in the fire. |
| 1 March 1970 | 106 | Vickers Viscount CF-THY collided in mid-air with Ercoupe 415 CF-SHN on approach to Vancouver International Airport. The Ercoupe pilot was killed. |
| 5 July 1970 | 621 | McDonnell Douglas DC-8-63 registration CF-TIW exploded from a fuel line rupture caused by engine 4 striking the runway in Toronto, Ontario, during a landing attempt. All 109 passengers/crew were killed. |
| 21 June 1973 | 890 | McDonnell Douglas DC-8-53, registration CF-TIJ caught fire and was burnt out during refuelling at Terminal 2, Toronto Pearson International Airport, Ontario; no fatalities. |
| 26 June 1978 | 189 | McDonnell Douglas DC-9-32, registration CF-TLV overran the runway in Toronto after a blown tire aborted the takeoff. Two of the 107 people on board were killed. |
| 17 September 1979 | 680 | McDonnell Douglas DC-9-32, registration C-FTLU left Logan International Airport in Boston, MA for Yarmouth, NS as Flight 680. Approximately 14 minutes after takeoff, the entire tailcone section of the aircraft separated resulting in rapid decompression at an altitude of 25,000 feet (7,600 m), leaving a large hole in the rear fuselage. A beverage cart and other items in the cabin were blown out of the aircraft over the Atlantic Ocean, but there were no fatalities or significant injuries. The aircraft safely returned to Boston. Fatigue cracks were determined to be the cause. This same aircraft would be destroyed by a fire nearly four years later on 2 June 1983 as Air Canada Flight 797. |
| 2 June 1982 | N/A | McDonnell Douglas DC-9-32 registration C-FTLY exploded during a maintenance period in Montreal, Quebec; no fatalities. |
| 2 June 1983 | 797 | McDonnell Douglas DC-9-32 C-FTLU had an electrical fire in the aft lavatory during flight, resulting in an emergency landing at Cincinnati/Northern Kentucky International Airport. During the emergency evacuation, the sudden influx of oxygen caused a flash fire throughout the cabin, resulting in the deaths of 23 of the 41 passengers, including Canadian folk singer Stan Rogers. All five crew members survived. The captain was the last person to exit the aircraft. This incident was also featured as "Fire Flight" of Canadian television series Mayday season 4 episode 3 (known as "Fiery Landing" of Air Emergency in the US, Air Crash Investigation in the UK and Australia). This is Air Canada's most recent fatal accident. |
| 23 July 1983 | 143 | Boeing 767-200 C-GAUN glided to an emergency landing in Gimli after running out of fuel 12,300 metres (40,400 ft) above Red Lake, Ontario. Some people suffered minor injuries during the evacuation due to the steep angle of the escape slides at the rear of the aircraft, caused by the collapse of the nose gear. This incident was the subject of the TV movie, Falling from the Sky: Flight 174 and the book, Freefall, by William Hoffer. This incident was also featured on the National Geographic Channel and Discovery Channel series Mayday season 5 episode 2. |
| 16 December 1997 | 646 | Air Canada Flight 646 departed Toronto-Lester B. Pearson International Airport, Ontario, at 9:24 PM eastern standard time on a scheduled flight to Fredericton, New Brunswick. On arrival, the Canadair CRJ100 aircraft, registration C-FSKI, experienced an unstabilized approach in poor visibility and stalled aerodynamically during a late go-around attempt. The aircraft skidded 2,100 feet (640 m) from the point of touchdown and hit a tree. An evacuation was conducted; however, seven passengers were trapped in the aircraft until rescued. Of the 39 passengers and 3 crew members, 9 were seriously injured and the rest received minor or no injuries. The accident occurred at 11:48 PM Atlantic standard time. Air Canada was heavily criticized in the media over its employees allegedly entering the crash site and removing the aircraft decals identifying its operator without the permission of the authorities. |
| 29 March 2015 | 624 | Air Canada Flight 624 was an Airbus A320 C-FTJP flying from Toronto Pearson International Airport to Halifax Stanfield International Airport. After 15 minutes in a holding pattern due to a severe winter storm and poor visibility, during approach in Halifax, the plane impacted the runway approach lights and power lines knocking out power and communications at the airport. It then impacted the ground 300m short of the runway, continuing on to impact the localizer antenna array, and breaking off its landing gear. The plane then touched down a second time and slid down the runway, losing one of its engines. All 133 passengers and five crew evacuated and survived. 23 people were sent to the hospital with non-life-threatening injuries. The aircraft was written off.[citation needed] |
| 7 July 2017 | 759 | At the conclusion of the regularly scheduled international passenger flight from Toronto to San Francisco, Air Canada Flight 759 nearly landed on a taxiway which already had four fully loaded and fuelled aircraft holding short for takeoff. A retired pilot stated the runway confusion that almost happened "probably came close to the greatest aviation disaster in history" as five aircraft and over 1,000 passengers were at imminent risk. |
