| Candidacy | Parties and alliances | Experience | Vice Presidential candidate |
| | | Andrónico Rodríguez (age 37) | AP | List Third System Movement (MTS) Socialist Revolutionary Party (PSR) Autonomist Movement for Work and Stability (MATE) | President of the Chamber of Senators (2020–2025) Senator for Cochabamba (2020–2025) | Mariana Prado |
| | | Pavel Aracena (age 56) | LYP-ADN | List Nationalist Democratic Action (ADN) We Are All Pando (PST) Autonomous Nationalities for the Change and Revolutionary Empowerment (NACER) | Engineer | Victor Hugo Núñez del Prado |
| | | Manfred Reyes Villa (age 71) | APB Súmate | List Autonomy for Bolivia – Súmate (APB Súmate) | Mayor of Cochabamba (1994–2000, 2021–present) Prefect of Cochabamba (2006–2008) Presidential candidate in 2002 and 2009 | Juan Carlos Medrano |
| | | Jorge "Tuto" Quiroga (age 66) | Libre | List Revolutionary Left Front (FRI) Social Democratic Movement (Demócratas) | 62nd President of Bolivia (2001–2002) 36th Vice President of Bolivia (1997–2001) Minister of Finance (1992) Presidential candidate in 2005 and 2014 | Juan Pablo Velasco |
| | | Jhonny Fernández (age 62) | FP | List Solidarity Civic Unity (UCS) Popular Original Movement (MOP) | Mayor of Santa Cruz de la Sierra (1995–2002, 2021–present) Presidential candidate in 2002 | Rosa Huanca |
| | | Eduardo Del Castillo (age 37) | MAS-IPSP | List Movement for Socialism – Political Instrument for the Sovereignty of the Peoples (MAS-IPSP) | Minister of Government (2020–2025) | Milan Berna |
| | | Samuel Doria Medina (age 67) | Unidad | List National Unity Front (UN) We Believe (Creemos) | Minister of Planning and Coordination (1991–1993) Presidential candidate in 2005, 2009 and 2014 | José Luis Lupo |
| | | Rodrigo Paz (age 58) | PDC | List First The People (PG) MIR New Ideas With Liberty (NUIL) Direct Democracy (DD) Christian Democratic Party (PDC) | Senator for Tarija (2020–2025) Mayor of Tarija (2015–2020) Deputy for Tarija (2002–2009) | Edmand Lara |