| Datetime, TV | Rank# | Opponent# | Result | Record | High points | High rebounds | High assists | Site (attendance) city, state |
| Non-conference regular season |
| November 4, 2024*8:30 p.m., SECN | No. 21 | vs. South Florida Jacksonville Sports Foundation Invitational | W 98–83 | 1–0 | 29 – Clayton Jr. | 6 – Tied | 3 – Martin | VyStar Veterans Memorial Arena (5,764)Jacksonville, FL |
| November 7, 2024*8:00 p.m., SECN+/ESPN+ | No. 21 | Jacksonville | W 81–60 | 2–0 | 23 – Condon | 7 – Alexis | 7 – Clayton Jr. | O'Connell Center (8,381)Gainesville, FL |
| November 11, 2024*7:00 p.m., SECN+/ESPN+ | No. 20 | Grambling State | W 86–62 | 3–0 | 14 – Chinyelu | 8 – Tied | 3 – Tied | O'Connell Center (7,857)Gainesville, FL |
| November 15, 2024*6:00 p.m., ACCN | No. 20 | at Florida State Rivalry | W 87–74 | 4–0 | 25 – Clayton Jr. | 12 – Condon | 3 – Tied | Donald L. Tucker Civic Center (9,797)Tallahassee, FL |
| November 19, 2024*7:00 p.m., SECN+/ESPN+ | No. 21 | Florida A&M | W 84–60 | 5–0 | 20 – Richard | 9 – Tied | 5 – Clayton Jr. | O'Connell Center (8,005)Gainesville, FL |
| November 22, 2024*7:00 p.m., SECN | No. 21 | Southern Illinois | W 93–68 | 6–0 | 32 – Martin | 9 – Martin | 5 – Martin | O'Connell Center (9,533)Gainesville, FL |
| November 28, 2024*2:30 p.m., ESPN | No. 18 | vs. Wake Forest ESPN Events Invitational Semifinals | W 75–58 | 7–0 | 21 – Clayton Jr. | 9 – Chinyelu | 3 – Clayton Jr. | State Farm Field House (3,191)Bay Lake, FL |
| November 29, 2024*3:30 p.m., ESPN | No. 18 | vs. Wichita State ESPN Events Invitational Final | W 88–51 | 8–0 | 19 – Clayton Jr. | 11 – Chinyelu | 5 – Richard | State Farm Field House (3,875)Bay Lake, FL |
| December 4, 2024*7:15 p.m., ESPN2 | No. 13 | Virginia ACC–SEC Challenge | W 87–69 | 9–0 | 27 – Clayton Jr. | 8 – Condon | 4 – Clayton Jr. | O'Connell Center (9,184)Gainesville, FL |
| December 14, 2024*3:30 p.m., SECN | No. 9 | vs. Arizona State Holiday Hoopsgiving | W 83–66 | 10–0 | 25 – Clayton Jr. | 11 – Martin | 6 – Martin | State Farm Arena (12,900)Atlanta, GA |
| December 17, 2024*7:00 p.m., ESPN | No. 7 | vs. North Carolina Jumpman Invitational | W 90–84 | 11–0 | 22 – Richard | 10 – Condon | 5 – Condon | Spectrum Center (16,058)Charlotte, NC |
| December 21, 2024*12:00 p.m., SECN | No. 7 | North Florida | W 99–45 | 12–0 | 26 – Richard | 12 – Alexis | 4 – Aberdeen | O'Connell Center (10,109)Gainesville, FL |
| December 29, 2024*1:00 p.m., SECN+/ESPN+ | No. 6 | Stetson | W 85–45 | 13–0 | 18 – Martin | 12 – Alexis | 7 – Clayton Jr. | O'Connell Center (10,676)Gainesville, FL |
| SEC regular season |
| January 4, 202511:00 a.m., ESPN | No. 6 | at No. 10 Kentucky Rivalry | L 100–106 | 13–1(0–1) | 33 – Clayton Jr. | 10 – Condon | 5 – Clayton Jr. | Rupp Arena (21,093)Lexington, KY |
| January 7, 20257:00 p.m., ESPN2 | No. 8 | No. 1 Tennessee | W 73–43 | 14–1(1–1) | 18 – Martin | 15 – Chinyelu | 5 – Clayton Jr. | O'Connell Center (11,011)Gainesville, FL |
| January 11, 20254:00 p.m., ESPN | No. 8 | at Arkansas | W 71–63 | 15–1(2–1) | 14 – Martin | 10 – Condon | 5 – Clayton Jr. | Bud Walton Arena (19,200)Fayetteville, AR |
| January 14, 20259:00 p.m., ESPNU | No. 5 | Missouri | L 82–83 | 15–2(2–2) | 28 – Clayton Jr. | 10 – Chinyelu | 3 – Condon | O'Connell Center (10,491)Gainesville, FL |
| January 18, 20254:00 p.m., ESPN2 | No. 5 | Texas | W 84–60 | 16–2(3–2) | 22 – Martin | 12 – Condon | 4 – Martin | O'Connell Center (11,107)Gainesville, FL |
| January 22, 20257:00 p.m., SECN | No. 5 | at South Carolina | W 70–69 | 17–2(4–2) | 22 – Richard | 7 – Condon | 7 – Clayton Jr. | Colonial Life Arena (14,930)Columbia, SC |
| January 25, 20253:30 p.m., SECN | No. 5 | Georgia | W 89–59 | 18–2(5–2) | 17 – Tied | 11 – Haugh | 5 – Clayton Jr. | O'Connell Center (11,187)Gainesville, FL |
| February 1, 202512:00 p.m., ESPN | No. 5 | at No. 8 Tennessee | L 44–64 | 18–3(5–3) | 10 – Clayton Jr. | 10 – Haugh | 2 – Richard | Thompson–Boling Arena (21,678)Knoxville, TN |
| February 4, 20257:00 p.m., SECN | No. 6 | Vanderbilt | W 86–75 | 19–3(6–3) | 21 – Richard | 9 – Tied | 4 – Tied | O'Connell Center (9,745)Gainesville, FL |
| February 8, 20254:00 p.m., ESPN2 | No. 6 | at No. 1 Auburn | W 90–81 | 20–3(7–3) | 19 – Clayton Jr. | 10 – Condon | 9 – Clayton Jr. | Neville Arena (9,121)Auburn, AL |
| February 11, 20257:00 p.m., ESPN2 | No. 3т | at No. 22 Mississippi State | W 81–68 | 21–3(8–3) | 20 – Aberdeen | 9 – Haugh | 8 – Haugh | Humphrey Coliseum (9,401)Starkville, MS |
| February 15, 20258:30 p.m., SECN | No. 3т | South Carolina | W 88–67 | 22–3(9–3) | 22 – Aberdeen | 6 – Tied | 8 – Clayton Jr. | O'Connell Center (10,853)Gainesville, FL |
| February 18, 20257:00 p.m., ESPN2 | No. 2 | Oklahoma | W 85–63 | 23–3(10–3) | 18 – Clayton Jr. | 8 – Richard | 3 – Aberdeen | O'Connell Center (10,513)Gainesville, FL |
| February 22, 20256:00 p.m., SECN | No. 2 | at LSU | W 79–65 | 24–3(11–3) | 19 – Chinyelu | 13 – Chinyelu | 5 – Richard | Pete Maravich Assembly Center (8,569)Baton Rouge, LA |
| February 25, 20257:00 p.m., SECN | No. 3 | at Georgia | L 83–88 | 24–4(11–4) | 30 – Richard | 9 – Handlogten | 5 – Clayton Jr. | Stegeman Coliseum (10,066)Athens, GA |
| March 1, 20258:30 p.m., SECN | No. 3 | No. 12 Texas A&M College GameDay | W 89–70 | 25–4(12–4) | 25 – Richard | 9 – Condon | 4 – Tied | O'Connell Center (10,784)Gainesville, FL |
| March 5, 20257:00 p.m., ESPN2 | No. 5 | at No. 7 Alabama | W 99–94 | 26–4(13–4) | 27 – Condon | 11 – Chinyelu | 8 – Clayton Jr. | Coleman Coliseum (13,474)Tuscaloosa, AL |
| March 8, 20256:00 p.m., SECN | No. 5 | Ole Miss | W 90–71 | 27–4(14–4) | 23 – Clayton Jr. | 15 – Condon | 8 – Clayton Jr. | O'Connell Center (11,191)Gainesville, FL |
| SEC tournament |
| March 14, 20257:00 p.m., SECN | (2) No. 4 | vs. (7) No. 21 Missouri Quarterfinals | W 95–81 | 28–4 | 18 – Clayton Jr. | 8 – Condon | 6 – Clayton Jr. | Bridgestone Arena (18,608)Nashville, TN |
| March 15, 20253:30 p.m., ESPN | (2) No. 4 | vs. (3) No. 5 Alabama Semifinals, College GameDay | W 104–82 | 29–4 | 22 – Clayton Jr. | 10 – Tied | 6 – Clayton Jr. | Bridgestone Arena (19,049)Nashville, TN |
| March 16, 20251:00 p.m., ESPN | (2) No. 4 | vs. (4) No. 8 Tennessee Championship | W 86–77 | 30–4 | 22 – Clayton Jr. | 9 – Condon | 3 – Richard | Bridgestone Arena (19,151)Nashville, TN |
| NCAA tournament |
| March 21, 20256:50 p.m., TNT | (1 W) No. 3 | vs. (16 W) Norfolk State First Round | W 95–69 | 31–4 | 23 – Clayton Jr. | 8 – Tied | 5 – Richard | Lenovo Center (19,178)Raleigh, NC |
| March 23, 202512:10 p.m., CBS | (1 W) No. 3 | vs. (8 W) UConn Second Round | W 77–75 | 32–4 | 23 – Clayton Jr. | 7 – Haugh | 4 – Condon | Lenovo Center (19,244)Raleigh, NC |
| March 27, 20257:39 p.m., TBS/TruTV | (1 W) No. 3 | vs. (4 W) No. 11 Maryland Sweet Sixteen | W 87–71 | 33–4 | 15 – Richard | 9 – Haugh | 4 – Haugh | Chase Center (16,417)San Francisco, CA |
| March 29, 20256:09 p.m., TBS/TruTV | (1 W) No. 3 | vs. (3 W) No. 9 Texas Tech Elite Eight | W 84–79 | 34–4 | 30 – Clayton Jr. | 11 – Haugh | 4 – Clayton Jr. | Chase Center (16,778)San Francisco, CA |
| April 5, 20256:09 p.m., CBS | (1 W) No. 3 | vs. (1 S) No. 4 Auburn Final Four, College GameDay | W 79–73 | 35–4 | 34 – Clayton Jr. | 9 – Chinyelu | 3 – Condon | Alamodome (68,252)San Antonio, TX |
| April 7, 20258:50 p.m., CBS | (1 W) No. 3 | vs. (1 MW) No. 2 Houston National Championship, College GameDay | W 65–63 | 36–4 | 18 – Richard | 8 – Richard | 7 – Clayton Jr. | Alamodome (66,602)San Antonio, TX |
| Non-conference game. from AP poll. (#) Tournament seedings in parentheses. W=West. S=South. MW=Midwest. All times are in Eastern Time. |