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There were six special elections to the United States House of Representatives in 2021 during the 117th United States Congress. All of the elections were won by the party previously holding the seat. Therefore, there were no net changes in party.
| District | Incumbent | This race | |||
| Member | Party | First elected | Results | Candidates | |
| Louisiana 5 | Vacant | Representative-elect Luke Letlow (R) died December 29, 2020, of COVID-19.New member elected March 20, 2021.Republican hold. | mw- ▌Y Julia Letlow (Republican) 64.9% ▌Sandra Christophe (Democratic) 27.3% ▌Chad Conerly (Republican) 5.3% | ||
| Louisiana 2 | Cedric Richmond | Democratic | 2010 | Incumbent resigned January 15, 2021, to serve as the director of the Office of Public Liaison and as a Senior Advisor to Joe Biden.New member elected April 24, 2021, after no candidate received a majority vote in the March 20 jungle primary.Democratic hold. | ▌Y Troy Carter (Democratic) 55.2% ▌Karen Carter Peterson (Democratic) 44.8% |
| New Mexico 1 | Deb Haaland | Democratic | 2018 | Incumbent resigned March 16, 2021, to become U.S. Secretary of the Interior.New member elected June 1, 2021.Democratic hold. | ▌Y Melanie Stansbury (Democratic) 60.3% ▌Mark Moores (Republican) 35.7% ▌Aubrey Dunn Jr. (Independent) 2.7% ▌Chris Manning (Libertarian) 1.3% |
| Texas 6 | Ron Wright | Republican | 2018 | Incumbent died February 7, 2021, of COVID-19.New member elected July 27, 2021, after no candidate received a majority vote in the May 1 jungle primary.Republican hold. | ▌Y Jake Ellzey (Republican) 53.3% ▌Susan Wright (Republican) 46.7% |
| Ohio 11 | Marcia Fudge | Democratic | 2008 (special) | Incumbent resigned March 10, 2021, to become U.S. Secretary of Housing and Urban Development.New member elected November 2, 2021.Democratic hold. | ▌Y Shontel Brown (Democratic) 78.9% ▌Laverne Gore (Republican) 21.1% |
| Ohio 15 | Steve Stivers | Republican | 2010 | Incumbent resigned May 16, 2021, to become the president and CEO of the Ohio Chamber of Commerce.New member elected November 2, 2021.Republican hold. | ▌Y Mike Carey (Republican) 58.3% ▌Allison Russo (Democratic) 41.7% |
| Party | Candidate | Votes | % | |
| Republican | Julia Letlow | 67,203 | 64.86 | |
| Democratic | Sandra Christophe | 28,255 | 27.27 | |
| Republican | Chad Conerly | 5,497 | 5.31 | |
| Republican | Robert Lansden | 929 | 0.90 | |
| Republican | Allen Guillory | 464 | 0.45 | |
| Independent | Jim Davis | 402 | 0.39 | |
| Republican | Sancha Smith | 334 | 0.32 | |
| Republican | Mendoza | 236 | 0.23 | |
| Independent | Jaycee Magnuson | 131 | 0.13 | |
| Republican | Richard H. Pannell | 67 | 0.06 | |
| Republican | Horace Melton III | 62 | 0.06 | |
| Republican | Errol Victor Sr. | 36 | 0.03 | |
| Total votes | 103,616 | 100.00 | ||
| Republican hold | ||||
| Party | Candidate | Votes | % | |
| Democratic | Troy Carter | 34,402 | 36.38 | |
| Democratic | Karen Carter Peterson | 21,673 | 22.92 | |
| Democratic | Gary Chambers Jr. | 20,163 | 21.31 | |
| Republican | Claston Bernard | 9,237 | 9.77 | |
| Republican | Chelsea Ardoin | 3,218 | 3.40 | |
| Republican | Greg Lirette | 2,349 | 2.48 | |
| Republican | Sheldon C. Vincent Sr. | 754 | 0.80 | |
| Democratic | Desiree Ontiveros | 699 | 0.74 | |
| Independent | Belden Batiste | 598 | 0.63 | |
| Democratic | Harold John | 403 | 0.43 | |
| Libertarian | Mindy McConnell | 323 | 0.34 | |
| Democratic | J. Christopher Johnson | 288 | 0.30 | |
| Democratic | Jenette M. Porter | 244 | 0.26 | |
| Democratic | Lloyd M. Kelly | 122 | 0.13 | |
| Independent | Brandon Jolicoeur | 94 | 0.10 | |
| Total votes | 94,567 | 100.00 | ||
| Party | Candidate | Votes | % | |
| Democratic | Troy Carter | 48,513 | 55.25 | |
| Democratic | Karen Carter Peterson | 39,297 | 44.75 | |
| Total votes | 87,810 | 100.00 | ||
| Democratic hold | ||||
| Party | Candidate | Votes | % | |
| Democratic | Melanie Stansbury | 79,837 | 60.36 | |
| Republican | Mark Moores | 47,111 | 35.62 | |
| Independent | Aubrey Dunn Jr. | 3,534 | 2.67 | |
| Libertarian | Chris Manning | 1,734 | 1.31 | |
| Write-in | 46 | 0.03 | ||
| Total votes | 132,262 | 100.00 | ||
| Democratic hold | ||||
| Party | Candidate | Votes | % | |
| Republican | Susan Wright | 15,852 | 19.21 | |
| Republican | Jake Ellzey | 10,851 | 13.85 | |
| Democratic | Jana Sanchez | 10,497 | 13.39 | |
| Republican | Brian Harrison | 8,476 | 10.81 | |
| Democratic | Shawn Lassiter | 6,964 | 8.89 | |
| Republican | John Anthony Castro | 4,321 | 5.51 | |
| Democratic | Tammy Allison Holloway | 4,238 | 5.41 | |
| Democratic | Lydia Bean | 2,920 | 3.73 | |
| Republican | Michael Wood | 2,503 | 3.19 | |
| Republican | Michael Ballantine | 2,224 | 2.84 | |
| Republican | Dan Rodimer | 2,086 | 2.66 | |
| Democratic | Daryl J. Eddings Sr. | 1,652 | 2.11 | |
| Republican | Mike Egan | 1,543 | 1.97 | |
| Democratic | Patrick Moses | 1,189 | 1.52 | |
| Democratic | Manuel R. Salazar III | 1,119 | 1.43 | |
| Republican | Sery Kim | 888 | 1.13 | |
| Republican | Travis Rodermund | 460 | 0.59 | |
| Independent | Adrian Mizher | 351 | 0.45 | |
| Democratic | Brian K. Stephenson | 271 | 0.35 | |
| Libertarian | Phil Gray | 265 | 0.34 | |
| Democratic | Matthew Hinterlong | 252 | 0.32 | |
| Republican | Jennifer Garcia Sharon | 150 | 0.19 | |
| Democratic | Chris Suprun | 102 | 0.13 | |
| Total votes | 78,374 | 100.00 | ||
| Party | Candidate | Votes | % | |
| Republican | Jake Ellzey | 20,837 | 53.27 | |
| Republican | Susan Wright | 18,279 | 46.73 | |
| Total votes | 39,116 | 100.00 | ||
| Republican hold | ||||
| Party | Candidate | Votes | % | |
| Democratic | Shontel Brown | 82,913 | 78.88 | |
| Republican | Laverne Gore | 22,198 | 21.12 | |
| Total votes | 105,111 | 100.00 | ||
| Democratic hold | ||||
| Party | Candidate | Votes | % | |
| Republican | Mike Carey | 94,501 | 58.30 | |
| Democratic | Allison Russo | 67,588 | 41.70 | |
| Total votes | 162,089 | 100.00 | ||
| Republican hold | ||||